MYBPC2 and MYBPH

Number of citations of the paper that reports this interaction (PubMedID 12154082)
0

Data Source:
HPRD (in vitro)

		MYBPC2	MYBPH
Description		myosin binding protein C2	myosin binding protein H
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol M Band Myosin Filament	M Band Myosin Filament
	Molecular Function	Actin Binding Protein Binding Structural Constituent Of Muscle	Protein Binding Structural Constituent Of Muscle
	Biological Process	Cell Adhesion Sarcomere Organization	Regulation Of Striated Muscle Contraction Cell Adhesion Sarcomere Organization
Pathways		Striated Muscle Contraction
Drugs
Diseases
GWAS		Primary biliary cholangitis ( 26394269)	Asthma ( 31959851) Clozapine-induced agranulocytosis ( 25187353)
Interacting Genes		31 interacting genes: ACTN2 AMOT AOC3 CCT6A CMYA5 COL12A1 DST DYSF FLNB FLNC FSD2 GABARAP GAS7 HSPA1B ITGB5 MAD2L2 MSN MYBPC1 MYBPH MYH8 MYOM2 NF2 PCDH12 PDE4DIP RANBP2 SDCBP SGCG TRIM63 TRIP11 TTN TULP3	5 interacting genes: CAPN3 MYBPC2 TTN UBL7 ZBTB38
Entrez ID		4606	4608
HPRD ID		01184	01186
Ensembl ID		ENSG00000086967	ENSG00000133055
Uniprot IDs		A0A140VJQ0 Q14324	Q13203
PDB IDs		2E7C 2EDK 2EDN
Enriched GO Terms of Interacting Partners?		Actin Filament-based Process M Band Actin Cytoskeleton Organization Cytoskeleton Organization Sarcomere Organization Structural Constituent Of Muscle Actomyosin Structure Organization Myosin Filament Z Disc Cytoskeletal Protein Binding Organelle Organization Actin Binding Cytoskeleton Focal Adhesion Titin Binding Positive Regulation Of Organelle Organization Cytoplasm Positive Regulation Of Supramolecular Fiber Organization Cell Adhesion Positive Regulation Of Cytoskeleton Organization Actin Filament Binding Myofibril Positive Regulation Of Microtubule Nucleation Positive Regulation Of Early Endosome To Late Endosome Transport Actin Cytoskeleton Integrin Binding Positive Regulation Of Protein Localization To Early Endosome Regulation Of Organelle Organization Positive Regulation Of Protein Localization To Endosome Positive Regulation Of Cellular Component Biogenesis Muscle Filament Sliding Phosphatidylinositol-4,5-bisphosphate Binding Filopodium Pseudopodium Actin-myosin Filament Sliding Regulation Of Early Endosome To Late Endosome Transport Muscle Contraction Stress Fiber Regulation Of Microtubule Nucleation Regulation Of Supramolecular Fiber Organization Extracellular Exosome Calcium Ion Binding Positive Regulation Of Cellular Component Organization Plasma Membrane Enzyme Binding Muscle Cell Development Sarcolemma Muscle System Process Regulation Of Organelle Assembly Regulation Of Intracellular Transport	Structural Constituent Of Muscle Sarcomere Organization Actomyosin Structure Organization M Band Myofibril Assembly Actin Cytoskeleton Organization Actin Filament-based Process Calcium-dependent Self Proteolysis Ligase Regulator Activity Positive Regulation Of Satellite Cell Activation Involved In Skeletal Muscle Regeneration Response To Calcium Ion Z Disc Titin-telethonin Complex Structural Molecule Activity Conferring Elasticity Sarcomerogenesis Regulation Of Satellite Cell Activation Involved In Skeletal Muscle Regeneration Skeletal Muscle Myosin Thick Filament Assembly Myosin Filament Assembly Positive Regulation Of Skeletal Muscle Tissue Regeneration G1 To G0 Transition Involved In Cell Differentiation Cytoskeleton Organization Skeletal Muscle Thin Filament Assembly Detection Of Muscle Stretch Telethonin Binding Regulation Of Skeletal Muscle Tissue Regeneration Sodium Ion Binding Membraneless Organelle Assembly Striated Muscle Thin Filament Negative Regulation Of Protein Sumoylation Self Proteolysis Cellular Response To Salt Stress Calcium-dependent Cysteine-type Endopeptidase Activity Response To Metal Ion Protein Kinase A Signaling Titin Binding G1 To G0 Transition Muscle Alpha-actinin Binding Cardiac Myofibril Assembly Muscle Filament Sliding Actinin Binding Mitotic Chromosome Condensation Protein Kinase Regulator Activity Actin-myosin Filament Sliding Protein K27-linked Ubiquitination Response To Salt Stress Myosin Filament Regulation Of Protein Sumoylation Muscle Cell Cellular Homeostasis Supramolecular Fiber Organization Response To Muscle Stretch
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