Wiki-Pi
About
Search
People
Updates
Search
MSX1 and ING4
Number of citations of the paper that reports this interaction (PubMedID
21988832
)
38
Data Source:
BioGRID
(two hybrid)
MSX1
ING4
Description
msh homeobox 1
inhibitor of growth family member 4
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Transcription Regulator Complex
Nuclear Periphery
Histone Acetyltransferase Complex
Nucleus
Nucleoplasm
Cytosol
Intermediate Filament Cytoskeleton
Molecular Function
Transcription Cis-regulatory Region Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
P53 Binding
DNA Binding
Protein Binding
Sequence-specific DNA Binding
Sequence-specific Double-stranded DNA Binding
Transcription Coactivator Activity
Protein Binding
Zinc Ion Binding
Histone H3K14 Acetyltransferase Activity
Histone H4K5 Acetyltransferase Activity
Histone H4K8 Acetyltransferase Activity
Histone H4K12 Acetyltransferase Activity
Metal Ion Binding
Histone H4K16 Acetyltransferase Activity
Histone H3K4me3 Reader Activity
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Cell Morphogenesis
In Utero Embryonic Development
Epithelial To Mesenchymal Transition
Heart Morphogenesis
Cardiac Conduction System Development
Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation
Regulation Of DNA-templated Transcription
Regulation Of Transcription By RNA Polymerase II
Transcription By RNA Polymerase II
Heart Development
Muscle Organ Development
Negative Regulation Of Cell Population Proliferation
Animal Organ Morphogenesis
Anterior/posterior Pattern Specification
Mesenchymal Cell Proliferation
Negative Regulation Of Gene Expression
Pituitary Gland Development
Signal Transduction Involved In Regulation Of Gene Expression
Negative Regulation Of Cell Growth
Embryonic Limb Morphogenesis
BMP Signaling Pathway
Positive Regulation Of BMP Signaling Pathway
Forebrain Development
Midbrain Development
Protein Localization To Nucleus
Embryonic Forelimb Morphogenesis
Embryonic Hindlimb Morphogenesis
Embryonic Nail Plate Morphogenesis
Middle Ear Morphogenesis
Odontogenesis Of Dentin-containing Tooth
Odontogenesis
Regulation Of Odontogenesis
Positive Regulation Of Odontogenesis
Embryonic Digit Morphogenesis
Negative Regulation Of Apoptotic Process
Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
Nose Development
Positive Regulation Of Cell Cycle
Negative Regulation Of DNA-templated Transcription
Positive Regulation Of Transcription By RNA Polymerase II
Embryonic Morphogenesis
Inner Ear Development
Stem Cell Differentiation
Protein Stabilization
Negative Regulation Of Striated Muscle Cell Differentiation
Cartilage Development
Roof Of Mouth Development
Face Morphogenesis
Bone Morphogenesis
Cartilage Morphogenesis
Mammary Gland Epithelium Development
Cell Surface Receptor Signaling Pathway Involved In Heart Development
Cellular Response To Nicotine
Activation Of Meiosis
Mesenchymal Cell Apoptotic Process
Negative Regulation Of Odontoblast Differentiation
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Positive Regulation Of Mesenchymal Cell Apoptotic Process
Regulation Of Cell Growth
Chromatin Organization
Chromatin Remodeling
Regulation Of DNA-templated Transcription
Protein Acetylation
Apoptotic Process
Negative Regulation Of Cell Population Proliferation
Positive Regulation Of Apoptotic Process
Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
Negative Regulation Of DNA-templated Transcription
Positive Regulation Of DNA-templated Transcription
Negative Regulation Of Growth
Regulation Of Cell Cycle
DNA Replication-dependent Chromatin Disassembly
Regulation Of Cell Cycle G2/M Phase Transition
Regulation Of DNA Biosynthetic Process
Pathways
Specification of the neural plate border
HATs acetylate histones
Drugs
Diseases
Isolated orofacial clefts, including: Cleft lip with or without cleft palate; Cleft palate
Tooth and nail syndrome; Witkop syndrome
Tooth agenesis; Hypodontia
GWAS
Allergic disease (asthma, hay fever or eczema) (
29083406
)
Breast cancer and/or colorectal cancer (
29698419
)
Congenital heart disease (
23708191
)
Electrocardiographic conduction measures (
19389651
)
Nonsyndromic cleft lip with cleft palate (
28232668
)
Interacting Genes
25 interacting genes:
CREBBP
DLX2
DLX5
HOXC8
ING4
LHX2
MED19
MSX2
NMNAT1
PAX3
PAX9
PIAS1
POU2F1
RBPMS
RGS7
SP1
SUMO1
SUMO2
TAF1
TBP
TLE1
TLE2
TLE4
TLE5
TP53
23 interacting genes:
BEX3
CDC34
EGLN1
EP300
GNL3
GRIPAP1
H3-4
H3C1
HNRNPD
HOXB9
JADE2
KAT7
MAPK8IP2
MSX1
MYC
NAV2
NOLC1
RELA
SUV39H1
TLX3
TP53
TRIM55
TRIM63
Entrez ID
4487
51147
HPRD ID
00866
09774
Ensembl ID
ENSG00000163132
ENSG00000111653
Uniprot IDs
P28360
Q9UNL4
PDB IDs
2K1J
2M1R
2PNX
2VNF
4AFL
Enriched GO Terms of Interacting Partners
?
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Gene Expression
Negative Regulation Of DNA-templated Transcription
Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of RNA Biosynthetic Process
Regulation Of Primary Metabolic Process
Chromatin
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Metabolic Process
Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of RNA Metabolic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Nucleus
Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Positive Regulation Of Biosynthetic Process
Positive Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Metabolic Process
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Metabolic Process
Nucleoplasm
Transcription Regulator Complex
Transcription Cis-regulatory Region Binding
Transcription Corepressor Activity
Negative Regulation Of Transcription By RNA Polymerase II
Animal Organ Morphogenesis
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Positive Regulation Of Transcription Initiation By RNA Polymerase II
RNA Polymerase II Core Promoter Sequence-specific DNA Binding
Positive Regulation Of DNA-templated Transcription Initiation
Regulation Of Transcription Initiation By RNA Polymerase II
DNA-binding Transcription Factor Binding
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Regulation Of DNA-templated Transcription Initiation
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Presynaptic Cytosol
Postsynaptic Cytosol
Nucleoplasm
Nucleus
Regulation Of Cellular Response To Stress
Chromatin Organization
Positive Regulation Of MiRNA Transcription
Chromatin Remodeling
Epigenetic Regulation Of Gene Expression
Positive Regulation Of MiRNA Metabolic Process
Regulation Of DNA Metabolic Process
Regulation Of MiRNA Transcription
Histone Acetyltransferase Complex
Regulation Of DNA Biosynthetic Process
Regulation Of MiRNA Metabolic Process
Chromatin
Negative Regulation Of Catabolic Process
Response To Actinomycin D
Regulation Of Telomere Maintenance
Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
DNA-templated Transcription
Regulation Of Primary Metabolic Process
Regulation Of Signal Transduction By P53 Class Mediator
Positive Regulation Of Transcription By RNA Polymerase II
Chromosome
Nucleic Acid Metabolic Process
Positive Regulation Of RNA Biosynthetic Process
Regulation Of Transcription By RNA Polymerase II
Histone H3 Acetyltransferase Activity
Internal Peptidyl-lysine Acetylation
Response To Hypoxia
Transcription Initiation-coupled Chromatin Remodeling
Circadian Rhythm
Chromatin Binding
Transcription Coactivator Binding
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Cellular Response To Nicotine
Cellular Response To Decreased Oxygen Levels
Cellular Response To Hypoxia
Histone H4K16 Acetyltransferase Activity
Positive Regulation Of Gene Expression, Epigenetic
Response To UV
Response To Decreased Oxygen Levels
RNA Metabolic Process
Regulation Of Gene Expression
Regulation Of Metabolic Process
Cellular Response To Oxygen Levels
Canonical NF-kappaB Signal Transduction
Anterior/posterior Pattern Specification
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?