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MSX1
Gene Name
msh homeobox 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Transcription Factor Complex
Cytoplasm
Molecular Function
RNA Polymerase II Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription
P53 Binding
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Cell Morphogenesis
In Utero Embryonic Development
Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation
Transcription From RNA Polymerase II Promoter
Muscle Organ Development
Negative Regulation Of Cell Proliferation
Anterior/posterior Pattern Specification
Mesenchymal Cell Proliferation
Pituitary Gland Development
Signal Transduction Involved In Regulation Of Gene Expression
Negative Regulation Of Cell Growth
Positive Regulation Of BMP Signaling Pathway
Midbrain Development
Protein Localization To Nucleus
Embryonic Forelimb Morphogenesis
Embryonic Hindlimb Morphogenesis
Embryonic Nail Plate Morphogenesis
Middle Ear Morphogenesis
Odontogenesis Of Dentin-containing Tooth
Regulation Of Odontogenesis
Negative Regulation Of Apoptotic Process
Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Protein Stabilization
Negative Regulation Of Striated Muscle Cell Differentiation
Palate Development
Face Morphogenesis
Bone Morphogenesis
Cartilage Morphogenesis
Mammary Gland Epithelium Development
BMP Signaling Pathway Involved In Heart Development
Cellular Response To Nicotine
Activation Of Meiosis
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Negative Regulation Of Transcription Regulatory Region DNA Binding
Positive Regulation Of Mesenchymal Cell Apoptotic Process
Pathways
Drugs
Diseases
GWAS
Congenital heart disease (
23708191
)
Electrocardiographic conduction measures (
19389651
)
Protein-protein Interactions
24 interactors:
AES
CREBBP
DLX2
DLX5
HOXC8
ING4
LHX2
MED19
MSX2
NMNAT1
PAX3
PAX9
PIAS1
POU2F1
RGS7
SP1
SUMO1
SUMO2
TAF1
TBP
TLE1
TLE2
TLE4
TP53
Entrez ID
4487
HPRD ID
00866
Ensembl ID
ENSG00000163132
Uniprot IDs
P28360
PDB IDs
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Transcription From RNA Polymerase II Promoter
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription, DNA-templated
RNA Biosynthetic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Gene Expression
Negative Regulation Of Cellular Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Cellular Nitrogen Compound Metabolic Process
Macromolecule Biosynthetic Process
RNA Metabolic Process
Gene Expression
Nitrogen Compound Metabolic Process
Regulation Of Metabolic Process
Biosynthetic Process
Positive Regulation Of Gene Expression
Organ Morphogenesis
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Macromolecule Biosynthetic Process
Embryonic Morphogenesis
Positive Regulation Of Metabolic Process
Anatomical Structure Morphogenesis
Positive Regulation Of Cellular Biosynthetic Process
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Peptidyl-lysine Modification
Notch Signaling Pathway
Pattern Specification Process
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Cellular Metabolic Process
Positive Regulation Of Proteasomal Protein Catabolic Process
Embryo Development
Organ Development
Regulation Of Cellular Process
Protein Sumoylation
Negative Regulation Of Binding
Regulation Of Signal Transduction
Tagcloud
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anomalies
cleft
clefts
cnv
cnvs
comprise
disrupting
doi
etiology
fgf8
foxe1
gli2
grouped
highlighting
irf6
jhg
journal
kif7
lip
mentioned
msx2
ofc
ofcs
orofacial
palate
postulated
satb2
ski
tceb3