ASPH and ASNA1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ASPH	ASNA1
Gene Name		aspartate beta-hydroxylase	arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Junctional Sarcoplasmic Reticulum Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane Cortical Endoplasmic Reticulum Sarcoplasmic Reticulum Membrane Sarcoplasmic Reticulum Lumen Calcium Channel Complex	Nucleus Nucleolus Cytoplasm Endoplasmic Reticulum Extracellular Vesicular Exosome
	Molecular Function	Peptide-aspartate Beta-dioxygenase Activity Structural Molecule Activity Calcium Ion Binding Protein Binding Structural Constituent Of Muscle Electron Carrier Activity Ion Channel Binding	Transporter Activity ATP Binding Arsenite Transmembrane Transporter Activity ATPase Activity Metal Ion Binding
	Biological Process	Detection Of Calcium Ion Muscle Contraction Pattern Specification Process Negative Regulation Of Cell Proliferation Positive Regulation Of Calcium Ion Transport Into Cytosol Regulation Of Cell Communication By Electrical Coupling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Regulation Of Protein Stability Activation Of Store-operated Calcium Channel Activity Response To ATP Limb Morphogenesis Peptidyl-aspartic Acid Hydroxylation Positive Regulation Of Proteolysis Positive Regulation Of Transcription, DNA-templated Oxidation-reduction Process Palate Development Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Face Morphogenesis Calcium Ion Transmembrane Transport Cellular Response To Calcium Ion Positive Regulation Of Intracellular Protein Transport Activation Of Cysteine-type Endopeptidase Activity Regulation Of Protein Depolymerization	Transport Metabolic Process Inorganic Anion Transport Protein Insertion Into ER Membrane
Pathways
Drugs		L-Aspartic Acid Succinic acid	Adenosine triphosphate
Diseases
GWAS
Protein-Protein Interactions		3 interactors: APP ASNA1 TRDN	13 interactors: APLN ASPH CACNA1A GPX7 HILPDA PFDN1 SEC61A1 SEC61B STATH STX5 TK1 TTR VAMP2
Entrez ID		444	439
HPRD ID		08996	03555
Ensembl ID		ENSG00000198363	ENSG00000198356
Uniprot IDs		B4DQ07 B7ZM96 Q12797	O43681
PDB IDs		3RCQ
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Organization Positive Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Endoplasmic Reticulum Membrane Organization Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Collateral Sprouting Axon Midline Choice Point Recognition Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Cell Communication By Electrical Coupling Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Axon Choice Point Recognition Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Cellular Metal Ion Homeostasis Protein Insertion Into ER Membrane Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Endomembrane System Organization Regulation Of Cardiac Muscle Cell Membrane Potential Negative Regulation Of Calcium Ion Transport Into Cytosol Cellular Cation Homeostasis Cellular Ion Homeostasis Cellular Localization Neuron Remodeling Metal Ion Homeostasis Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Sarcoplasmic Reticulum Calcium Ion Transport Cellular Chemical Homeostasis Regulation Of Cell Communication By Electrical Coupling Ion Homeostasis Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Cellular Copper Ion Homeostasis Protein Insertion Into Membrane Negative Regulation Of Cation Channel Activity Cellular Homeostasis Copper Ion Homeostasis Suckling Behavior Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Microtubule-based Process Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Membrane Organization Chemical Homeostasis Positive Regulation Of Cation Channel Activity	Protein Localization To Membrane Membrane Organization Transport Establishment Of Protein Localization To Membrane Calcium Ion-dependent Exocytosis Secretion Vesicle Fusion Cytoplasmic Transport Acid Secretion Cellular Protein Localization Cerebellar Molecular Layer Development Fetal Process Involved In Parturition Organelle Fusion Vestibular Nucleus Development Skeletal Muscle Cell Proliferation Peptidyl-aspartic Acid Hydroxylation Autocrine Signaling Intracellular Protein Transport SRP-dependent Cotranslational Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Endomembrane System Organization Body Fluid Secretion Neurotransmitter Secretion Golgi Disassembly Cerebellum Maturation Eosinophil Degranulation Musculoskeletal Movement, Spinal Reflex Action Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Cerebellum Development Protein Localization To Endoplasmic Reticulum Gamma-aminobutyric Acid Secretion Metencephalon Development Membrane Fusion Protein Localization Energy Reserve Metabolic Process Regulation Of Neurotransmitter Levels Thyroid Hormone Transport Regulation Of Acetylcholine Secretion, Neurotransmission Retrograde Protein Transport, ER To Cytosol Cell Growth Establishment Of Localization In Cell Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Regulation Of Exocytosis Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Rhythmic Synaptic Transmission Response To Cortisol Thymidine Metabolic Process
Tagcloud ?		3a 3b 5d 6a 6b b3ylp chelate chme cyano dihalodiplatinum diplatinum emitters formulae halide isopropyl lantern maxima paddle phosphorescence phosphorescent photoemissive pop pt pyrophosphite sigma tddft tunable wheel xmmct	als14 als8 amyotrophic anchored anticipated belongs cofactors converts establishes faf1 fedax ffat hexamer homo immunoprecipitates interactors msp oligosaccharyl p97 phenylalanine proficient repertoire rpn2 trc uba ubiquitinated ubx vapa vapb
Tagcloud (Difference) ?		3a 3b 5d 6a 6b b3ylp chelate chme cyano dihalodiplatinum diplatinum emitters formulae halide isopropyl lantern maxima paddle phosphorescence phosphorescent photoemissive pop pt pyrophosphite sigma tddft tunable wheel xmmct	als14 als8 amyotrophic anchored anticipated belongs cofactors converts establishes faf1 fedax ffat hexamer homo immunoprecipitates interactors msp oligosaccharyl p97 phenylalanine proficient repertoire rpn2 trc uba ubiquitinated ubx vapa vapb
Tagcloud (Intersection) ?