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BPY2B and UBE3A
Number of citations of the paper that reports this interaction (PMID
12207887
)
5
Data Source:
HPRD
(in vivo, two hybrid)
BPY2B
UBE3A
Gene Name
basic charge, Y-linked, 2B
ubiquitin protein ligase E3A
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Proteasome Complex
Nucleus
Cytoplasm
Cytosol
Molecular Function
Protein Binding
HECT Domain Binding
Transcription Coactivator Activity
Ubiquitin-protein Transferase Activity
Protein Binding
Ligase Activity
Biological Process
Spermatogenesis
Single Fertilization
Ovarian Follicle Development
Proteolysis
Ubiquitin-dependent Protein Catabolic Process
Brain Development
Positive Regulation Of Phosphatidylinositol 3-kinase Signaling
Viral Process
Androgen Receptor Signaling Pathway
Sperm Entry
Regulation Of Circadian Rhythm
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Protein Autoubiquitination
Prostate Gland Growth
Protein K48-linked Ubiquitination
Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Drugs
Diseases
GWAS
Cardiac hypertrophy (
21348951
)
Obesity-related traits (
23251661
)
Protein-Protein Interactions
1 interactors:
UBE3A
80 interactors:
ADRM1
AFG3L1P
AFTPH
AHSP
ANXA1
APP
AR
ARC
ASAP3
ATG9A
BARD1
BLK
BPY2
BPY2B
BPY2C
BRCA1
C11orf49
CDKN1B
CEBPZ
DLG1
EAPP
EID1
EIF4G1
HBA1
HPCAL4
HSPA4
JADE1
KLHL38
LCK
MAGEA8
MCM7
MDM2
MEOX2
NDUFA13
NELFCD
NOMO2
PARVA
PDE1B
PGR
PML
POLE4
PRDX1
PSAP
PSMC3
PSMD4
RAD23A
RAD23B
RARA
RMI1
RNF2
SACS
SCAMP1
SCRIB
SGK223
SHBG
SMAD9
SOD1
SUMO3
TAT
TBC1D14
TCF19
TP53
TRIM65
TSC2
TTC3
UBB
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2E1
UBE2G1
UBE2G2
UBE2L3
UBE2L6
UBQLN2
UCHL5
YOD1
YWHAE
YWHAZ
Entrez ID
442867
7337
HPRD ID
12530
03375
Ensembl ID
ENSG00000183795
ENSG00000114062
Uniprot IDs
O14599
Q05086
Q9BUI6
Q9H2G0
PDB IDs
1C4Z
1D5F
1EQX
2KR1
4GIZ
Enriched GO Terms of Interacting Partners
?
Sperm Entry
Prostate Gland Growth
Protein K48-linked Ubiquitination
Androgen Receptor Signaling Pathway
Protein Autoubiquitination
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Phosphatidylinositol 3-kinase Signaling
Ovarian Follicle Development
Prostate Gland Development
Intracellular Steroid Hormone Receptor Signaling Pathway
Regulation Of Phosphatidylinositol 3-kinase Signaling
Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Regulation Of Circadian Rhythm
Ovulation Cycle Process
Organ Growth
Female Gonad Development
Ovulation Cycle
Development Of Primary Female Sexual Characteristics
Single Fertilization
Protein Polyubiquitination
Fertilization
Intracellular Receptor Signaling Pathway
Regulation Of Protein Ubiquitination
Gonad Development
Development Of Primary Sexual Characteristics
Protein Polyubiquitination
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Regulation Of Proteolysis
Positive Regulation Of Proteolysis
Protein Catabolic Process
Response To Stress
Cellular Response To Organic Substance
Regulation Of Mitotic Cell Cycle Phase Transition
Protein Modification By Small Protein Conjugation
Negative Regulation Of Mitotic Cell Cycle
Regulation Of Cellular Protein Metabolic Process
Regulation Of Cell Cycle Phase Transition
Negative Regulation Of Cell Cycle
Regulation Of Protein Metabolic Process
Response To Organic Substance
Cellular Macromolecule Catabolic Process
Positive Regulation Of Cellular Metabolic Process
Protein Ubiquitination
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Regulation Of Protein Catabolic Process
Positive Regulation Of Cell Cycle Arrest
Positive Regulation Of Metabolic Process
Regulation Of Mitotic Cell Cycle
DNA Damage Response, Signal Transduction By P53 Class Mediator
Mitotic Cell Cycle Checkpoint
Cell Death
Death
Cell Cycle Checkpoint
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Apoptotic Process
Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Signal Transduction Involved In DNA Damage Checkpoint
Regulation Of Cell Cycle G1/S Phase Transition
Signal Transduction In Response To DNA Damage
Signal Transduction Involved In Cell Cycle Checkpoint
Regulation Of Cell Cycle Arrest
Programmed Cell Death
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Regulation Of Catalytic Activity
Proteasomal Protein Catabolic Process
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Protein K48-linked Ubiquitination
Regulation Of Cell Cycle
Catabolic Process
Mitotic G1 DNA Damage Checkpoint
Mitotic G1/S Transition Checkpoint
Tagcloud
?
2h5
accompanies
anova
dynactin
gadd45a
gtf2h5
invites
keuls
macaques
malfunctioning
nbn1
ndd
ndds
newman
ovx
perimenopausal
presenilin1
proteosome
psen1
rad23a
raphe
scna
serotonin
speculation
subserving
symptomology
ube2d3
ubea5
ubiquinase
Tagcloud (Difference)
?
2h5
accompanies
anova
dynactin
gadd45a
gtf2h5
invites
keuls
macaques
malfunctioning
nbn1
ndd
ndds
newman
ovx
perimenopausal
presenilin1
proteosome
psen1
rad23a
raphe
scna
serotonin
speculation
subserving
symptomology
ube2d3
ubea5
ubiquinase
Tagcloud (Intersection)
?