ATXN3 and TEX11

Number of citations of the paper that reports this interaction (PMID 16713569)
214

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ATXN3	TEX11
Gene Name		ataxin 3	testis expressed 11
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrial Matrix Cytosol Nuclear Matrix Mitochondrial Membrane Nuclear Inclusion Body	Synaptonemal Complex Central Element
	Molecular Function	Ubiquitin-specific Protease Activity Protein Binding Omega Peptidase Activity Ubiquitin Protein Ligase Binding Identical Protein Binding ATPase Binding Lys63-specific Deubiquitinase Activity Lys48-specific Deubiquitinase Activity	Protein Binding
	Biological Process	Microtubule Cytoskeleton Organization Nucleotide-excision Repair Transcription, DNA-templated Regulation Of Transcription, DNA-templated Ubiquitin-dependent Protein Catabolic Process Misfolded Or Incompletely Synthesized Protein Catabolic Process Synaptic Transmission Nervous System Development Regulation Of Cell-substrate Adhesion Actin Cytoskeleton Organization Cellular Response To Heat Monoubiquitinated Protein Deubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Intermediate Filament Cytoskeleton Organization Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination Cellular Response To Misfolded Protein	Resolution Of Meiotic Recombination Intermediates Meiotic Gene Conversion Male Meiosis Chromosome Segregation Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Male Gonad Development Fertilization Negative Regulation Of Apoptotic Process Chiasma Assembly
Pathways
Drugs
Diseases
GWAS		Height ( 18391950 18391951) Orofacial clefts ( 22419666)
Protein-Protein Interactions		43 interactors: ANXA7 APP ARHGAP19 ARHGDIA ASIC1 C16orf70 CASP1 CDKN1A CSNK2B DNM2 EWSR1 GSK3B HDAC6 KAT2B MKNK1 NCOR1 PARK2 PICK1 PJA1 PSMD7 RAD23A RAD23B RFFL RPS6KA1 SQSTM1 STUB1 SUMO1 TEX11 TK1 TRAF6 TRIM54 TRIM55 TRIM63 TUBA1A TUBB UBB UBC UBE2L3 UBE2S UBE4B UBQLN1 USP21 VCP	48 interactors: ALS2CR11 ATXN3 BEX1 C10orf82 C14orf105 C6orf226 CDKN1A CENPP CFAP53 COL20A1 CXCL14 DUSP21 DUSP6 EFHC1 FAM156A FBF1 GATAD2B HYI ING3 KIAA0408 KIAA1217 LIN37 MAD1L1 MAPK9 MAPKBP1 MEF2BNB MEF2BNB-MEF2B MYEF2 NECAB2 NEFL NRIP1 POM121 PPP1R18 REXO1L6P RIBC1 RIBC2 SEPT1 SNW1 SNX7 SPERT STMN2 TBC1D22B TCHP TIPIN TSC22D4 UTP14C VIL1 ZNF414
Entrez ID		4287	56159
HPRD ID		06131	02256
Ensembl ID		ENSG00000066427	ENSG00000120498
Uniprot IDs		P54252	Q8IYF3
PDB IDs		1YZB 2AGA 2DOS 2JRI 2KLZ
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Ubiquitin-dependent Protein Catabolic Process Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Regulation Of Proteolysis Protein Modification By Small Protein Conjugation Protein Polyubiquitination Cellular Macromolecule Catabolic Process Protein Ubiquitination Cellular Response To Organic Substance Positive Regulation Of Cellular Protein Metabolic Process Response To Organic Substance Positive Regulation Of Cellular Metabolic Process Cellular Protein Modification Process Regulation Of Catalytic Activity Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Response To Stimulus Cellular Response To Stimulus Positive Regulation Of Metabolic Process Proteolysis Regulation Of Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Ubiquitination Positive Regulation Of Proteolysis Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Response To Abiotic Stimulus Cellular Response To Stress Positive Regulation Of Protein Modification Process Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Cell Death Catabolic Process Response To Growth Factor Protein Metabolic Process Regulation Of Metabolic Process Apoptotic Process Programmed Cell Death Regulation Of Apoptotic Process Cell Death Death Positive Regulation Of Ubiquitin-protein Transferase Activity Cellular Response To Growth Factor Stimulus Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Protein Catabolic Process
Tagcloud ?		14q32 amplifies ataxia atm atnx3 break breaks cag deposited eventually expansions glutamine inactivated inefficient joseph machado mjd neurodegeneration nonetheless pnkp polymorphic polynucleotide polyq sca3 spinocerebellar strand telangiectasia tri untreatable	17beta abundantly anchors ccnb1 cfos competed cytoskeleton diarylpropionitrile erbeta esr1 esr2 estradiol gc germ hpip infertility interacting klinefelter ks modulates nongenomic partners proapoptotic spermatocytes spermatogenic spermatogonia spermatogonial testes testis
Tagcloud (Difference) ?		14q32 amplifies ataxia atm atnx3 break breaks cag deposited eventually expansions glutamine inactivated inefficient joseph machado mjd neurodegeneration nonetheless pnkp polymorphic polynucleotide polyq sca3 spinocerebellar strand telangiectasia tri untreatable	17beta abundantly anchors ccnb1 cfos competed cytoskeleton diarylpropionitrile erbeta esr1 esr2 estradiol gc germ hpip infertility interacting klinefelter ks modulates nongenomic partners proapoptotic spermatocytes spermatogenic spermatogonia spermatogonial testes testis
Tagcloud (Intersection) ?