TEX11 and PTPDC1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TEX11	PTPDC1
Description		testis expressed 11	protein tyrosine phosphatase domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Condensed Nuclear Chromosome Synaptonemal Complex Central Element Chromosome	Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding	Phosphoprotein Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Hydrolase Activity
	Biological Process	Resolution Of Meiotic Recombination Intermediates Meiotic Gene Conversion Apoptotic Process Male Meiosis Chromosome Segregation Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Male Meiotic Nuclear Division Male Gonad Development Fertilization Ectopic Germ Cell Programmed Cell Death Negative Regulation Of Apoptotic Process Chiasma Assembly Negative Regulation Of Developmental Process Meiotic Cell Cycle Negative Regulation Of Reproductive Process	Cell Projection Organization Cilium Assembly
Pathways
Drugs
Diseases
GWAS		Mean corpuscular volume ( 29403010) Waist circumference ( 28552196)	Birth weight ( 31043758) Esophageal adenocarcinoma ( 24121790) Heel bone mineral density ( 30598549) Height ( 20881960) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Parkinson's disease ( 26227905) Type 2 diabetes ( 30054458) Waist-hip ratio ( 25673412) Waist-to-hip ratio adjusted for body mass index ( 25673412)
Interacting Genes		91 interacting genes: ATXN3 BCL2L2 BEX1 BORCS8 BORCS8-MEF2B BRMS1L CATSPERT CBY2 CCDC198 CCND2 CCND3 CD74 CDKN1A CDKN2D CENPP CEP55 CEP85L CFAP53 CLK1 CNOT7 COL20A1 CXCL14 DMTN DUSP21 DUSP6 EFHC1 EXOSC1 EXOSC5 FAAP20 FAM156A FAM161B FAM217A FBF1 GATAD2B GPSM3 GRXCR1 HOXB5 HYI ING3 KANK2 KCTD10 KIAA0408 KIAA1217 KRT6B LIN37 LRCH2 LRRC36 LSM2 MAD1L1 MAPK9 MAPKBP1 MORF4L1 MRFAP1 MRFAP1L1 MTA1 MYEF2 NECAB2 NEFL NRIP1 PEX39 PIAS1 POM121 PPP1R18 PRPSAP2 PTPDC1 QKI REXO1L6P RIBC1 RIBC2 SCAF8 SEPTIN1 SH3GLB2 SHOC1 SNW1 SNX32 SNX6 SNX7 SOX5 SPMIP5 STMN2 SUPT5H TBC1D22B TCHP TIPIN TOPBP1 TSC22D4 TSG101 USP15 UTP14C VIL1 ZNF414	7 interacting genes: AATK CRKL ERBB3 ERBB4 LMTK2 MID2 TEX11
Entrez ID		56159	138639
HPRD ID		02256	06689
Ensembl ID		ENSG00000120498	ENSG00000158079
Uniprot IDs		Q8IYF3	A0A087WTF0 A2A3K4 A8K0X7
PDB IDs
Enriched GO Terms of Interacting Partners?		Axonemal A Tubule Inner Sheath Protein Binding Cytoskeleton Sperm Motility Flagellated Sperm Motility Cilium-dependent Cell Motility RNA Exonuclease Activity Cilium Movement Involved In Cell Motility Cyclin D2-CDK4 Complex Negative Regulation Of Peptidyl-tyrosine Phosphorylation Motile Cilium Spindle Pole	Neuregulin Receptor Activity Cell Death Apoptotic Process Programmed Cell Death Protein Tyrosine Kinase Activity Protein Kinase Activity ERBB2 Signaling Pathway Kinase Activity Animal Organ Development Heart Development Transferase Activity Epidermal Growth Factor Receptor Signaling Pathway Basal Plasma Membrane Neuromuscular Junction ERBB Signaling Pathway Establishment Of Planar Polarity Involved In Nephron Morphogenesis Meiotic Gene Conversion Positive Regulation Of Intracellular Signal Transduction Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of MAPK Cascade Helper T Cell Diapedesis Positive Regulation Of Cardiac Muscle Tissue Development ERBB3:ERBB2 Complex Central Nervous System Morphogenesis Myosin VI Binding Gene Conversion Male Gonad Development Neuron Apoptotic Process Chordate Pharynx Development Cerebellar Neuron Development ATP Binding Protein Autophosphorylation Epidermal Growth Factor Receptor Activity Male Meiosis Chromosome Segregation Gonad Development Fertilization Cardiac Muscle Tissue Regeneration Olfactory Bulb Interneuron Differentiation Enzyme-linked Receptor Protein Signaling Pathway Regulation Of MAPK Cascade ErbB-3 Class Receptor Binding Neuregulin Binding Regulation Of Cardiac Muscle Tissue Development ERBB2-ERBB4 Signaling Pathway Positive Regulation Of Signal Transduction Positive Regulation Of ERK1 And ERK2 Cascade Parathyroid Gland Development ERBB4-ERBB4 Signaling Pathway Chiasma Assembly Reproductive Structure Development
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