TEX11 and QKI

Number of citations of the paper that reports this interaction (PubMedID 30217970)
38

Data Source:
BioGRID (two hybrid)

		TEX11	QKI
Description		testis expressed 11	QKI, KH domain containing RNA binding
Image		No pdb structure
GO Annotations	Cellular Component	Condensed Nuclear Chromosome Synaptonemal Complex Central Element Chromosome	Nucleus Cytoplasm Cytosol Cytoplasmic Stress Granule Synapse
	Molecular Function	Protein Binding	Nucleic Acid Binding DNA Binding Transcription Coactivator Activity RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding SH3 Domain Binding MiRNA Binding Internal N(7)-methylguanine-containing RNA Reader Activity
	Biological Process	Resolution Of Meiotic Recombination Intermediates Meiotic Gene Conversion Apoptotic Process Male Meiosis Chromosome Segregation Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Male Meiotic Nuclear Division Male Gonad Development Fertilization Ectopic Germ Cell Programmed Cell Death Negative Regulation Of Apoptotic Process Chiasma Assembly Negative Regulation Of Developmental Process Meiotic Cell Cycle Negative Regulation Of Reproductive Process	Vasculogenesis MRNA Processing Regulation Of Translation Spermatid Development Intracellular MRNA Localization Axon Ensheathment RNA Splicing Positive Regulation Of Gene Expression Regulation Of Epithelial To Mesenchymal Transition Microglia Differentiation Negative Regulation Of Angiogenesis Negative Regulation Of Translation Cell Differentiation Positive Regulation Of Myelination Negative Regulation Of Type I Interferon Production Stress Granule Assembly Vascular Associated Smooth Muscle Cell Differentiation Myelination Long-chain Fatty Acid Biosynthetic Process Positive Regulation Of Cholesterol Biosynthetic Process Regulation Of Macrophage Differentiation Negative Regulation Of Macrophage Differentiation Positive Regulation Of DNA-templated Transcription Regulation Of MRNA Splicing, Via Spliceosome MRNA Stabilization Regulation Of Astrocyte Differentiation Positive Regulation Of Oligodendrocyte Differentiation MRNA Transport Regulation Of Cell Development Negative Regulation Of Cold-induced Thermogenesis Spliceosome-depend Formation Of Circular RNA Negative Regulation Of 3'-UTR-mediated MRNA Stabilization Myofibroblast Contraction Regulation Of Multicellular Organismal Development Negative Regulation Of MiRNA Catabolic Process
Pathways			Signaling by BRAF and RAF1 fusions
Drugs
Diseases
GWAS		Mean corpuscular volume ( 29403010) Waist circumference ( 28552196)	Cataracts ( 34127677) Diastolic blood pressure ( 27841878) Diisocyanate-induced asthma ( 25918132) Fasting insulin ( 34059833) Height ( 31562340) Hemoglobin ( 32888494) Incident myocardial infarction ( 26950853) Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444) Platelet distribution width ( 32888494) Red blood cell count ( 29403010) Refractive error ( 32231278) Response to TNF antagonist treatment ( 18615156) Seasonality and depression ( 30217971) Triglyceride levels ( 32203549) Type 2 diabetes ( 30297969 30718926)
Interacting Genes		91 interacting genes: ATXN3 BCL2L2 BEX1 BORCS8 BORCS8-MEF2B BRMS1L CATSPERT CBY2 CCDC198 CCND2 CCND3 CD74 CDKN1A CDKN2D CENPP CEP55 CEP85L CFAP53 CLK1 CNOT7 COL20A1 CXCL14 DMTN DUSP21 DUSP6 EFHC1 EXOSC1 EXOSC5 FAAP20 FAM156A FAM161B FAM217A FBF1 GATAD2B GPSM3 GRXCR1 HOXB5 HYI ING3 KANK2 KCTD10 KIAA0408 KIAA1217 KRT6B LIN37 LRCH2 LRRC36 LSM2 MAD1L1 MAPK9 MAPKBP1 MORF4L1 MRFAP1 MRFAP1L1 MTA1 MYEF2 NECAB2 NEFL NRIP1 PEX39 PIAS1 POM121 PPP1R18 PRPSAP2 PTPDC1 QKI REXO1L6P RIBC1 RIBC2 SCAF8 SEPTIN1 SH3GLB2 SHOC1 SNW1 SNX32 SNX6 SNX7 SOX5 SPMIP5 STMN2 SUPT5H TBC1D22B TCHP TIPIN TOPBP1 TSC22D4 TSG101 USP15 UTP14C VIL1 ZNF414	90 interacting genes: ALG13 ANKHD1 APP ATXN1 BAG4 BCAS2 CALD1 CARM1 CCDC59 CCND3 CDKN2D CEBPA CPSF7 DAZ1 DAZ4 DEPP1 DMRTB1 EIF4ENIF1 FBXO7 FHL3 FUBP3 HCLS1 HLCS HNRNPH2 HNRNPK HNRNPLL IL7R KIF21B LSM3 LSM5 MBNL1 MBNL2 MIR141 MIR19B2 MIR200A MIR34B MIR34C MIR7-1 MRPL44 MSI2 NABP1 NEIL3 NIP7 NXF1 PCBP1 PCBP2 PCBP3 PCBP4 PCGF5 PIAS1 PRKAB2 PRMT1 PRPF39 PRPF6 PRRC2B PSMF1 PTBP1 PTBP2 RALY RBFOX1 RBFOX2 RBM11 RBM14 RBM23 RBM42 RBM7 RBPMS RNF138 RPL9 SECISBP2 SERF2 SLAIN1 SNRPA SNRPC TEX11 THAP1 TIAL1 TNRC6A TRNAU1AP TSG101 TXNL4A U2AF2 UNKL USH1C UTP6 WDR77 YTHDF1 YTHDF3 ZC3H10 ZMAT5
Entrez ID		56159	9444
HPRD ID		02256	06691
Ensembl ID		ENSG00000120498	ENSG00000112531
Uniprot IDs		Q8IYF3	Q8WY44 Q96PU8
PDB IDs			4JVH
Enriched GO Terms of Interacting Partners?		Axonemal A Tubule Inner Sheath Protein Binding Cytoskeleton Sperm Motility Flagellated Sperm Motility Cilium-dependent Cell Motility RNA Exonuclease Activity Cilium Movement Involved In Cell Motility Cyclin D2-CDK4 Complex Negative Regulation Of Peptidyl-tyrosine Phosphorylation Motile Cilium Spindle Pole	RNA Binding Nucleic Acid Binding Regulation Of RNA Splicing MRNA Binding RNA Splicing Regulation Of MRNA Metabolic Process MRNA Processing MRNA Metabolic Process Nucleic Acid Metabolic Process RNA Processing RNA Metabolic Process Nucleus Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Nucleobase-containing Compound Metabolic Process Spliceosomal Complex Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Macromolecule Metabolic Process Ribonucleoprotein Complex Negative Regulation Of MRNA Metabolic Process Post-transcriptional Regulation Of Gene Expression MRNA Splicing, Via Spliceosome Regulation Of Metabolic Process Regulation Of Macromolecule Metabolic Process RNA Splicing, Via Transesterification Reactions Nucleoplasm Negative Regulation Of RNA Splicing Negative Regulation Of Macromolecule Metabolic Process Regulation Of Primary Metabolic Process MRNA 3'-UTR Binding Cytoplasmic Stress Granule Regulation Of RNA Metabolic Process Negative Regulation Of Metabolic Process U4/U6 X U5 Tri-snRNP Complex Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process MiRNA-mediated Post-transcriptional Gene Silencing Negative Regulation Of Biosynthetic Process Negative Regulation Of Gene Expression Regulatory NcRNA-mediated Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Commitment Complex Regulation Of Translation Viral RNA Genome Replication Regulation Of MRNA Stability Negative Regulation Of RNA Metabolic Process
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