TEX11 and CCDC198

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		TEX11	CCDC198
Description		testis expressed 11	coiled-coil domain containing 198
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Condensed Nuclear Chromosome Synaptonemal Complex Central Element Chromosome	Plasma Membrane Membrane Cytoplasmic Vesicle
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Resolution Of Meiotic Recombination Intermediates Meiotic Gene Conversion Apoptotic Process Male Meiosis Chromosome Segregation Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Male Meiotic Nuclear Division Male Gonad Development Fertilization Ectopic Germ Cell Programmed Cell Death Negative Regulation Of Apoptotic Process Chiasma Assembly Negative Regulation Of Developmental Process Meiotic Cell Cycle Negative Regulation Of Reproductive Process	Energy Homeostasis
Pathways
Drugs
Diseases
GWAS		Mean corpuscular volume ( 29403010) Waist circumference ( 28552196)
Interacting Genes		91 interacting genes: ATXN3 BCL2L2 BEX1 BORCS8 BORCS8-MEF2B BRMS1L CATSPERT CBY2 CCDC198 CCND2 CCND3 CD74 CDKN1A CDKN2D CENPP CEP55 CEP85L CFAP53 CLK1 CNOT7 COL20A1 CXCL14 DMTN DUSP21 DUSP6 EFHC1 EXOSC1 EXOSC5 FAAP20 FAM156A FAM161B FAM217A FBF1 GATAD2B GPSM3 GRXCR1 HOXB5 HYI ING3 KANK2 KCTD10 KIAA0408 KIAA1217 KRT6B LIN37 LRCH2 LRRC36 LSM2 MAD1L1 MAPK9 MAPKBP1 MORF4L1 MRFAP1 MRFAP1L1 MTA1 MYEF2 NECAB2 NEFL NRIP1 PEX39 PIAS1 POM121 PPP1R18 PRPSAP2 PTPDC1 QKI REXO1L6P RIBC1 RIBC2 SCAF8 SEPTIN1 SH3GLB2 SHOC1 SNW1 SNX32 SNX6 SNX7 SOX5 SPMIP5 STMN2 SUPT5H TBC1D22B TCHP TIPIN TOPBP1 TSC22D4 TSG101 USP15 UTP14C VIL1 ZNF414	27 interacting genes: CBY2 FAM9B FHL2 FHL3 FKBP6 GOLGA2 GOPC HOOK2 HSF2BP IQGAP3 KIFC3 KRT31 KRT34 KRT40 LZTS2 MDFI MTUS2 PDE4DIP PFDN5 PNMA1 SIAH1 SMAD3 SSX2IP TEX11 TRAF1 TRAF2 TRIM27
Entrez ID		56159	55195
HPRD ID		02256	12628
Ensembl ID		ENSG00000120498	ENSG00000100557
Uniprot IDs		Q8IYF3	B7ZL43 E9PSE9 F5GWJ3 Q05C89 Q9NVL8
PDB IDs
Enriched GO Terms of Interacting Partners?		Axonemal A Tubule Inner Sheath Protein Binding Cytoskeleton Sperm Motility Flagellated Sperm Motility Cilium-dependent Cell Motility RNA Exonuclease Activity Cilium Movement Involved In Cell Motility Cyclin D2-CDK4 Complex Negative Regulation Of Peptidyl-tyrosine Phosphorylation Motile Cilium Spindle Pole	Identical Protein Binding Supramolecular Fiber Organization Synaptonemal Complex Cytoplasm Organelle Organization Cytoskeleton Centrosome Cycle Cytoskeleton Organization Structural Constituent Of Skin Epidermis Thioesterase Binding Microtubule Intermediate Filament Organization Microtubule Organizing Center Organization Developmental Process Involved In Reproduction Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Centrosome Microtubule Binding Reproductive Process BHLH Transcription Factor Binding Meiotic Cell Cycle Protein Binding Microtubule-based Process Regulation Of Wnt Signaling Pathway Negative Regulation Of Lung Blood Pressure Nuclear Mineralocorticoid Receptor Binding RNA Polymerase III Assembly RNA Polymerase I Assembly Tumor Necrosis Factor Receptor Binding TORC2 Complex Disassembly Meiotic Gene Conversion Negative Regulation Of Anion Channel Activity Primary Ureteric Bud Growth Myosin VI Light Chain Binding Morphogenesis Of An Epithelium Signal Transduction Involved In Regulation Of Gene Expression Intermediate Filament
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