MGMT and PRKCA

  • Number of citations of the paper that reports this interaction (PMID 10667577)
  • 6
  • Data Source:
  • HPRD (in vitro, in vivo)

MGMT

PRKCA

Gene Name O-6-methylguanine-DNA methyltransferase protein kinase C, alpha
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Response to temozolomide ( 23047291)
  • Waist-to-hip circumference ratio (interaction) ( 23192594)
  • Height ( 22021425)
  • Post-traumatic stress disorder (asjusted for relatedness) ( 23726511)
  • Ventricular conduction ( 21076409)
Protein-Protein Interactions 8 interactors: CREBBP CSNK2A1 CSNK2A2 EP300 ESR1 PRKACA PRKCA UBA1 210 interactors: ACTA1 ADAP1 ADCY5 ADD3 ADRA1B ADRBK1 AFAP1 AKAP12 AKAP5 ANXA2 ANXA7 APLP2 ARHGEF1 ATP1A1 ATP2B1 ATP2B2 AVPR1A BCL2 BTG2 BTK C1QBP CASR CBL CD163 CD5 CD9 CDC42 CDKN2A CFTR CHAT CISH CORO1B CREM CYP3A4 CYTH2 DDX5 DGKD DGKZ DLG4 DLX3 DNM1 DVL2 EDF1 EEF1D EGFR EIF4E EIF4EBP1 ELAVL1 ENTPD5 EP300 EWSR1 EZR F11R FAS FBXO25 FLNA FLNC FSCN1 GABRB3 GABRG2 GABRR1 GABRR2 GFAP GFPT1 GJA1 GJB1 GLI3 GMFB GNA12 GNA15 GNB2L1 GPM6A GRIA1 GRIA2 GRIA4 GRIN1 GRIN2A GRIN2B GRM1 GRM5 GSK3A GSK3B HABP4 HAND1 HAND2 HES1 HIST1H1A HIST1H1B HIST1H1C HIST1H1D HIST1H1E HIST1H1T HIST1H3A HIST3H3 HLA-A HMGA1 HMGA2 HMGB1 HMGN1 HMGN2 HSP90AA1 HSPA1A HSPB8 IKBKB INSR ITGB1 ITGB2 ITGB4 ITPKA ITPKB KCNE1 KCNE4 KCNQ2 KIT KLF5 KRT18 LCK LMNA LMNB1 MARCKS MBP MGMT MTOR MYLK MYOD1 NCF1 NFATC1 NFE2L2 NFKBIA NOS1 NR1H2 NRGN NUMB OGG1 OPRD1 PA2G4 PAM PDLIM7 PEA15 PEBP1 PFKFB1 PFKFB2 PICK1 PLCB1 PLD1 PLD2 POLB PPARA PPARG PPP1R14A PRKCZ PRKG1 PSMB4 PTGIR PTPN11 PTPN12 PTPN6 RAC1 RAF1 RALBP1 RARA RBCK1 RGS19 RGS2 RGS7 RHO RHOA RNF31 RPL10 RRAD SACM1L SCRIB SCTR SDC2 SDC4 SDPR SELL SEMG1 SEMG2 SHC1 SLC1A1 SLC6A9 SNAP23 SNAP25 SPAG1 SPP1 SRC STXBP1 STXBP3 SYK TBXA2R TEP1 TERT THOC5 TIAM1 TNNI3 TNNT2 TNP1 TNP2 TOP2A TP53 TRIM29 TRIM41 TRPC3 TRPV6 VCL VTN XK YWHAG YWHAZ
Entrez ID 4255 5578
HPRD ID 01135 01498
Ensembl ID ENSG00000154229
Uniprot IDs B4DEE8 P16455 P17252 Q7Z727
PDB IDs 1EH6 1EH7 1EH8 1QNT 1T38 1T39 1YFH 2ELI 3IW4 4DNL
Enriched GO Terms of Interacting Partners?
Tagcloud ?
bcnu  bis  cenu  chloroethyl  chloroethylnitrosourea  complementing  confirm  correlations  cytotoxicity  deficiency  ercc2  excision  innate  lines  methylguanine  methyltransferase  modifying  nitrosourea  nucleotide  o6  poor  r  repair  resistance  rich  rodent  sensitivity  uv  xpd 
american  artiodactyla  assigned  block  blot  cattle  chr  conservative  conserved  cow  electrophoresis  erbb2  hybrid  hybridization  localization  localized  means  mink  nf1  pepa  pig  rara  representatives  sheep  southern  swine  synteny  tk1  umph2 
Tagcloud (Difference) ?
bcnu  bis  cenu  chloroethyl  chloroethylnitrosourea  complementing  confirm  correlations  cytotoxicity  deficiency  ercc2  excision  innate  lines  methylguanine  methyltransferase  modifying  nitrosourea  nucleotide  o6  poor  r  repair  resistance  rich  rodent  sensitivity  uv  xpd 
american  artiodactyla  assigned  block  blot  cattle  chr  conservative  conserved  cow  electrophoresis  erbb2  hybrid  hybridization  localization  localized  means  mink  nf1  pepa  pig  rara  representatives  sheep  southern  swine  synteny  tk1  umph2 
Tagcloud (Intersection) ?