MBD1 and OASL

Number of citations of the paper that reports this interaction (PMID 14728690)
3

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		MBD1	OASL
Gene Name		methyl-CpG binding domain protein 1	2-5-oligoadenylate synthetase-like
Image
Gene Ontology Annotations	Cellular Component	Heterochromatin Nucleus Cytoplasm Nuclear Matrix Nuclear Speck	Nucleolus Cytoplasm Cytosol Membrane
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Zinc Ion Binding Methyl-CpG Binding	2'-5'-oligoadenylate Synthetase Activity DNA Binding Double-stranded RNA Binding ATP Binding Poly(A) RNA Binding Thyroid Hormone Receptor Binding
	Biological Process	Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated	Metabolic Process Response To Virus Cytokine-mediated Signaling Pathway Negative Regulation Of Viral Genome Replication Defense Response To Virus Interferon-gamma-mediated Signaling Pathway Type I Interferon Signaling Pathway
Pathways			Interferon gamma signaling Interferon Signaling Cytokine Signaling in Immune system Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Chronic lymphocytic leukemia ( 20062064)	C-reactive protein ( 22939635) Cardiovascular disease risk factors ( 21943158) N-glycan levels ( 21203500)
Protein-Protein Interactions		24 interactors: APP ATF7IP ATF7IP2 ATXN1L CBX4 CBX5 CHAF1A ECT2 HDAC3 HIPK3 HTT OASL PIAS1 PIAS2 RNF2 SETDB1 SMAD1 SMAD3 SMAD5 SMAD7 SMAD9 SUV39H1 TENM1 ZNF512B	3 interactors: MBD1 SEZ6L2 THRA
Entrez ID		4152	8638
HPRD ID		01133	04473
Ensembl ID		ENSG00000141644	ENSG00000135114
Uniprot IDs		A8K654 B4DI41 B4DUR3 K7ELI2 K7EQZ4 K7ESN0 Q9UIS9	Q15646
PDB IDs		1D9N 1IG4	1WH3
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Heterocycle Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Cellular Process Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Positive Regulation Of Gene Expression Mesonephros Development Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated Kidney Epithelium Development Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Macromolecule Biosynthetic Process Response To Transforming Growth Factor Beta Cellular Response To Growth Factor Stimulus BMP Signaling Pathway Regulation Of Cell Differentiation Response To Growth Factor Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Protein Sumoylation Cellular Protein Modification Process Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Chromatin Organization Peptidyl-lysine Modification	Negative Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Positive Regulation Of Female Receptivity Negative Regulation Of DNA-templated Transcription, Initiation Negative Regulation Of Transcription Initiation From RNA Polymerase II Promoter Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Female Courtship Behavior Regulation Of Thyroid Hormone Mediated Signaling Pathway Regulation Of Female Receptivity Female Mating Behavior Type I Pneumocyte Differentiation Transcription From RNA Polymerase II Promoter Cytoplasmic Sequestering Of Transcription Factor Cytoplasmic Sequestering Of Protein Cartilage Condensation Regulation Of DNA-templated Transcription, Initiation Thyroid Gland Development Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Myotube Differentiation Mating Behavior Regulation Of Myeloid Cell Apoptotic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription Factor Import Into Nucleus Mating Response To Cold Regulation Of Lipid Catabolic Process Regulation Of Myotube Differentiation Lung Epithelial Cell Differentiation Positive Regulation Of Striated Muscle Cell Differentiation Lung Cell Differentiation Lung Epithelium Development Negative Regulation Of Protein Import Into Nucleus Negative Regulation Of Protein Localization To Nucleus Positive Regulation Of Muscle Cell Differentiation Negative Regulation Of Intracellular Protein Transport Regulation Of Transcription Factor Import Into Nucleus Negative Regulation Of Cellular Metabolic Process Regulation Of Striated Muscle Cell Differentiation Erythrocyte Differentiation Steroid Hormone Mediated Signaling Pathway Erythrocyte Homeostasis Transcription, DNA-templated Negative Regulation Of Intracellular Transport RNA Biosynthetic Process Negative Regulation Of Protein Complex Assembly Myeloid Cell Homeostasis Hormone-mediated Signaling Pathway Maintenance Of Protein Location In Cell
Tagcloud ?		adipose arousal brown entered euthermic expensive ground hdac4 hdacs hibernating hibernation hp1 ictidomys imparted interbout lined lys23 packing repressors reversal rewarms rose shivering squirrels thermogenesis thirteen torpor tridecemlineatus winter	4a abrogate adaptor altogether antiviral argue cardif ccl5 cleaving compromised counteracts cxcl10 cxcl11 cxcl9 ectopically evasion hcv hepatocytes ifnbeta il28a il29 impairing innate irf3 isg15 isg56 isgs ns3 polyprotein
Tagcloud (Difference) ?		adipose arousal brown entered euthermic expensive ground hdac4 hdacs hibernating hibernation hp1 ictidomys imparted interbout lined lys23 packing repressors reversal rewarms rose shivering squirrels thermogenesis thirteen torpor tridecemlineatus winter	4a abrogate adaptor altogether antiviral argue cardif ccl5 cleaving compromised counteracts cxcl10 cxcl11 cxcl9 ectopically evasion hcv hepatocytes ifnbeta il28a il29 impairing innate irf3 isg15 isg56 isgs ns3 polyprotein
Tagcloud (Intersection) ?