MBD1

Gene Name		methyl-CpG binding domain protein 1
Image
Gene Ontology Annotations	Cellular Component	Heterochromatin Nucleus Cytoplasm Nuclear Matrix Nuclear Speck
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Zinc Ion Binding Methyl-CpG Binding
	Biological Process	Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Chronic lymphocytic leukemia ( 20062064)
Protein-protein Interactions		24 interactors: APP ATF7IP ATF7IP2 ATXN1L CBX4 CBX5 CHAF1A ECT2 HDAC3 HIPK3 HTT OASL PIAS1 PIAS2 RNF2 SETDB1 SMAD1 SMAD3 SMAD5 SMAD7 SMAD9 SUV39H1 TENM1 ZNF512B
Entrez ID		4152
HPRD ID		01133
Ensembl ID		ENSG00000141644
Uniprot IDs		A8K654 B4DI41 B4DUR3 K7ELI2 K7EQZ4 K7ESN0 Q9UIS9
PDB IDs		1D9N 1IG4
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Heterocycle Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Cellular Process Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Positive Regulation Of Gene Expression Mesonephros Development Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated Kidney Epithelium Development Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Macromolecule Biosynthetic Process Response To Transforming Growth Factor Beta Cellular Response To Growth Factor Stimulus BMP Signaling Pathway Regulation Of Cell Differentiation Response To Growth Factor Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Protein Sumoylation Cellular Protein Modification Process Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Chromatin Organization Peptidyl-lysine Modification
Tagcloud ?		adipose arousal brown entered euthermic expensive ground hdac4 hdacs hibernating hibernation hp1 ictidomys imparted interbout lined lys23 packing repressors reversal rewarms rose shivering squirrels thermogenesis thirteen torpor tridecemlineatus winter