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MBD1 and ATF7IP2
Number of citations of the paper that reports this interaction (PubMedID
15691849
)
0
Data Source:
HPRD
(in vitro)
MBD1
ATF7IP2
Description
methyl-CpG binding domain protein 1
activating transcription factor 7 interacting protein 2
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Chromosome
Nuclear Matrix
Nuclear Speck
Nucleus
Transcription Regulator Complex
Molecular Function
DNA Binding
Protein Binding
Zinc Ion Binding
Methyl-CpG Binding
Double-stranded Methylated DNA Binding
Unmethylated CpG Binding
Metal Ion Binding
Transcription Coregulator Activity
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
DNA Methylation-dependent Constitutive Heterochromatin Formation
Transcription By RNA Polymerase II
Negative Regulation Of DNA-templated Transcription
Regulation Of DNA-templated Transcription
Pathways
SUMOylation of transcription cofactors
Drugs
Diseases
GWAS
Chronic lymphocytic leukemia (
28165464
)
Copper levels (
26025379
)
Disease progression in age-related macular degeneration (adjusted for baseline) (
29346644
)
Disease progression to choroidal neovascularization form in age-related macular degeneration (
29346644
)
Night sleep phenotypes (
27126917
)
Response to antipsychotic treatment (
20195266
)
Interacting Genes
47 interacting genes:
APP
ATF7IP
ATF7IP2
ATXN1L
C1QBP
CBX4
CBX5
CCDC136
CHAF1A
COPE
DVL3
ECT2
EEF1G
GRN
HDAC3
HIPK3
HTT
HUNK
JAG2
LTBP3
LTBP4
MDFI
MEGF6
NELL1
NELL2
NOTCH1
NOTCH3
OASL
PIAS1
PIAS2
POMGNT1
RNF2
SETDB1
SLC25A3
SMAD1
SMAD3
SMAD5
SMAD7
SMAD9
SNAPC2
SP1
SUV39H1
TENM1
TIAM1
TNC
ZNF384
ZNF512B
7 interacting genes:
FSD2
MAP1LC3A
MBD1
MED4
NUP62
SETDB1
SP1
Entrez ID
4152
80063
HPRD ID
01133
16517
Ensembl ID
ENSG00000141644
ENSG00000166669
Uniprot IDs
A0A994J7H0
A8K654
B4DI41
B4DUR3
Q9UIS9
Q5U623
PDB IDs
1D9N
1IG4
4D4W
5W9Q
6D1T
Enriched GO Terms of Interacting Partners
?
Heteromeric SMAD Protein Complex
SMAD Protein Signal Transduction
Negative Regulation Of Transcription By RNA Polymerase II
Transforming Growth Factor Beta Receptor Signaling Pathway
I-SMAD Binding
SMAD Protein Complex
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Metabolic Process
Regulation Of Transcription By RNA Polymerase II
Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Chromatin Binding
Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Negative Regulation Of Metabolic Process
Negative Regulation Of Macromolecule Metabolic Process
Regulation Of Ossification
DEAD/H-box RNA Helicase Binding
Positive Regulation Of Developmental Process
Transcription Corepressor Activity
Kidney Epithelium Development
Regulation Of Macromolecule Metabolic Process
Regulation Of Primary Metabolic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of MiRNA Transcription
Response To Growth Factor
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Regulation Of Metabolic Process
Regulation Of Gene Expression
Transcription Regulator Complex
Nucleus
Regulation Of Cell Population Proliferation
Regulation Of MiRNA Metabolic Process
Ureteric Bud Development
SUMO Ligase Activity
Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Ossification
Nucleoplasm
Mesonephric Tubule Development
Mesonephric Epithelium Development
Epigenetic Regulation Of Gene Expression
Cellular Response To Growth Factor Stimulus
Positive Regulation Of Cell Differentiation
Auditory Receptor Cell Fate Commitment
Osteoblast Fate Commitment
SUMO Transferase Activity
DNA Methylation-dependent Constitutive Heterochromatin Formation
Constitutive Heterochromatin Formation
Positive Regulation Of Hydrogen Sulfide Biosynthetic Process
Cellular Response To Wortmannin
Double-stranded Methylated DNA Binding
Heterochromatin Formation
Negative Regulation Of Gene Expression, Epigenetic
Cellular Response To Starvation
Response To Wortmannin
Cellular Response To Zinc Ion Starvation
Histone H3K9 Trimethyltransferase Activity
Histone H3K9 Monomethyltransferase Activity
PTB Domain Binding
Phospholipid Binding
Nuclear Pore Central Transport Channel
Positive Regulation Of Mitotic Cytokinetic Process
Positive Regulation Of Protein Localization To Centrosome
Mitotic Centrosome Separation
Response To Iron(II) Ion
Cellular Response To Oxygen-glucose Deprivation
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Tagcloud (Intersection)
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