MBD1 and ATF7IP2

Number of citations of the paper that reports this interaction (PMID 15691849)
27

Data Source:
HPRD (in vitro)

		MBD1	ATF7IP2
Gene Name		methyl-CpG binding domain protein 1	activating transcription factor 7 interacting protein 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Heterochromatin Nucleus Cytoplasm Nuclear Matrix Nuclear Speck	Nucleus Nucleoplasm Nucleolus Cytoplasm
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Zinc Ion Binding Methyl-CpG Binding
	Biological Process	Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Chronic lymphocytic leukemia ( 20062064)	Response to antipsychotic treatment ( 20195266)
Protein-Protein Interactions		24 interactors: APP ATF7IP ATF7IP2 ATXN1L CBX4 CBX5 CHAF1A ECT2 HDAC3 HIPK3 HTT OASL PIAS1 PIAS2 RNF2 SETDB1 SMAD1 SMAD3 SMAD5 SMAD7 SMAD9 SUV39H1 TENM1 ZNF512B	3 interactors: MBD1 SETDB1 SP1
Entrez ID		4152	80063
HPRD ID		01133	16517
Ensembl ID		ENSG00000141644	ENSG00000166669
Uniprot IDs		A8K654 B4DI41 B4DUR3 K7ELI2 K7EQZ4 K7ESN0 Q9UIS9	Q5U623
PDB IDs		1D9N 1IG4
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Heterocycle Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Cellular Process Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Positive Regulation Of Gene Expression Mesonephros Development Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated Kidney Epithelium Development Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Macromolecule Biosynthetic Process Response To Transforming Growth Factor Beta Cellular Response To Growth Factor Stimulus BMP Signaling Pathway Regulation Of Cell Differentiation Response To Growth Factor Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Protein Sumoylation Cellular Protein Modification Process Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Chromatin Organization Peptidyl-lysine Modification	Blastocyst Development Sequestering Of Nodal From Receptor Via Nodal Binding Negative Regulation Of Nodal Signaling Pathway Determination Of Left/right Asymmetry In Lateral Mesoderm Regulation Of Nodal Signaling Pathway Sequestering Of Extracellular Ligand From Receptor Transcription, DNA-templated RNA Biosynthetic Process Histone H3-K9 Trimethylation Negative Regulation Of Activin Receptor Signaling Pathway Positive Regulation By Host Of Viral Transcription Embryonic Process Involved In Female Pregnancy In Utero Embryonic Development Skeletal System Development Lateral Mesoderm Development Enucleate Erythrocyte Differentiation Extracellular Negative Regulation Of Signal Transduction RNA Metabolic Process Histone H3-K9 Methylation Inner Cell Mass Cell Proliferation Atrial Septum Development Megakaryocyte Differentiation Regulation Of Activin Receptor Signaling Pathway Definitive Hemopoiesis Trophectodermal Cell Differentiation Gene Expression Peptidyl-lysine Trimethylation Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Blastocyst Growth Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Interaction With Symbiont Histone H3-K9 Modification Blastocyst Formation Embryonic Camera-type Eye Morphogenesis Negative Regulation Of BMP Signaling Pathway Embryonic Eye Morphogenesis Positive Regulation Of Viral Transcription Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Embryo Development Ventricular Septum Development Nucleobase-containing Compound Metabolic Process
Tagcloud ?		adipose arousal brown entered euthermic expensive ground hdac4 hdacs hibernating hibernation hp1 ictidomys imparted interbout lined lys23 packing repressors reversal rewarms rose shivering squirrels thermogenesis thirteen torpor tridecemlineatus winter
Tagcloud (Difference) ?		adipose arousal brown entered euthermic expensive ground hdac4 hdacs hibernating hibernation hp1 ictidomys imparted interbout lined lys23 packing repressors reversal rewarms rose shivering squirrels thermogenesis thirteen torpor tridecemlineatus winter
Tagcloud (Intersection) ?