DDI1 and GPANK1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DDI1	GPANK1
Description		DDI proteasomal shuttling factor 1	G-patch domain and ankyrin repeats 1
Image			No pdb structure
GO Annotations	Cellular Component
	Molecular Function	Aspartic-type Endopeptidase Activity Protein Binding Peptidase Activity Hydrolase Activity	Nucleic Acid Binding Protein Binding
	Biological Process	Proteolysis Proteasomal Protein Catabolic Process Regulation Of Protein Stability Cellular Response To Hydroxyurea Regulation Of DNA Stability
Pathways
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)	Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Febrile seizures (MMR vaccine-related) ( 25344690) Hip circumference adjusted for BMI ( 34021172) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Ulcerative colitis ( 28067908)
Interacting Genes		18 interacting genes: ADRM1 CCL28 CYGB DVL2 FAM161B GPANK1 GSK3A KLHL42 MFHAS1 NCCRP1 RALGAPA2 RPP25 SDS TEKT3 TRAF2 UBC UBE2K USP2	90 interacting genes: ABI2 AKAP8L ANAPC11 AP1B1 AP2B1 APP BAG4 C1QTNF2 CADPS CCDC184 CCDC33 CCDC85B CEACAM6 CIMIP2B CYSRT1 DDI1 DHX15 DISC1 ECM1 EFS FTO GOLGA2 GOLGA6L9 GPRASP3 GRB2 HNRNPH1 HOMEZ HSF2BP HYI INKA1 INSC KANK2 KATNBL1 KCTD9 KRT75 KRTAP10-8 KRTAP12-2 KRTAP13-3 KRTAP19-5 KRTAP19-6 LDOC1 LIG4 LZTS2 MAGED1 MAGOHB MDFI MEOX1 MEOX2 METTL27 METTL6 MID2 MORN3 NADSYN1 NFKBID NR1H3 NUTM1 OIP5 PATZ1 PAX6 PBX4 PFDN5 PLAAT1 PNMA1 PPARA PPP4C PRDM6 PTH1R RIMBP3C RTL8C SORBS3 SPATA2 STMN3 STX5 TEPSIN TFCP2 TLE5 TRAF2 TRAPPC2L TRIM23 TRIM27 TSC1 TTC19 TTC23 VBP1 VHL ZBTB16 ZBTB8OS ZMAT5 ZNF688 ZRANB1
Entrez ID		414301	7918
HPRD ID		13128	00810
Ensembl ID		ENSG00000170967	ENSG00000204438
Uniprot IDs		Q8WTU0	A0A024RCU2 A0A0G2JHL1 A0A1U9X7R4 B2RA66 O95872
PDB IDs		3S8I
Enriched GO Terms of Interacting Partners?		Modification-dependent Protein Catabolic Process Ubiquitin Protein Ligase Binding Proteolysis Involved In Protein Catabolic Process Macromolecule Catabolic Process Catabolic Process Proteolysis Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Ubiquitin-dependent Protein Catabolic Process Protein Catabolic Process Regulation Of JNK Cascade Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of UDP-glucose Catabolic Process TORC2 Complex Disassembly Regulation Of Brood Size Outer Acrosomal Membrane Fatty Acid Peroxidase Activity Nitric Oxide Dioxygenase Activity, Heme Protein As Donor	Protein Binding Nucleus Regulation Of Supramolecular Fiber Organization Asymmetric Cell Division
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