DDI1 and RPP25

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DDI1	RPP25
Description		DDI proteasomal shuttling factor 1	ribonuclease P/MRP subunit p25
Image
GO Annotations	Cellular Component		Ribonuclease MRP Complex Nucleus Nucleoplasm Nucleolus Multimeric Ribonuclease P Complex Centriolar Satellite
	Molecular Function	Aspartic-type Endopeptidase Activity Protein Binding Peptidase Activity Hydrolase Activity	Nucleic Acid Binding RNA Binding Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding
	Biological Process	Proteolysis Proteasomal Protein Catabolic Process Regulation Of Protein Stability Cellular Response To Hydroxyurea Regulation Of DNA Stability	TRNA 5'-leader Removal RRNA Processing TRNA Processing
Pathways			tRNA processing in the nucleus Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)	Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Myocardial infarction ( 33532862) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
Interacting Genes		18 interacting genes: ADRM1 CCL28 CYGB DVL2 FAM161B GPANK1 GSK3A KLHL42 MFHAS1 NCCRP1 RALGAPA2 RPP25 SDS TEKT3 TRAF2 UBC UBE2K USP2	22 interacting genes: ABI2 BACH2 BANP DDI1 HOMEZ KRT15 LDOC1 LRRC73 PDLIM7 PICK1 PNMA1 POP1 POP4 POP5 POP7 RBPMS RPP14 RPP38 SAT1 SF3B4 TERF2IP ZNF438
Entrez ID		414301	54913
HPRD ID		13128	15276
Ensembl ID		ENSG00000170967	ENSG00000178718
Uniprot IDs		Q8WTU0	Q9BUL9
PDB IDs		3S8I	6AHR 6AHU 6CWX 6LT7
Enriched GO Terms of Interacting Partners?		Modification-dependent Protein Catabolic Process Ubiquitin Protein Ligase Binding Proteolysis Involved In Protein Catabolic Process Macromolecule Catabolic Process Catabolic Process Proteolysis Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Ubiquitin-dependent Protein Catabolic Process Protein Catabolic Process Regulation Of JNK Cascade Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of UDP-glucose Catabolic Process TORC2 Complex Disassembly Regulation Of Brood Size Outer Acrosomal Membrane Fatty Acid Peroxidase Activity Nitric Oxide Dioxygenase Activity, Heme Protein As Donor	Ribonuclease P RNA Binding Multimeric Ribonuclease P Complex Ribonuclease P Activity TRNA 5'-leader Removal TRNA 5'-end Processing Ribonuclease MRP Complex Nucleolar Ribonuclease P Complex Ribonuclease P Complex TRNA Processing TRNA Metabolic Process Nucleolus RNA Processing Nucleoplasm RNA Binding RRNA Processing Nucleus RRNA Metabolic Process Regulation Of Arp2/3 Complex-mediated Actin Nucleation Regulation Of Actin Nucleation Spermidine Binding RNA Metabolic Process Primary Adaptive Immune Response Involving T Cells And B Cells Spermidine Acetylation Putrescine Catabolic Process Zonula Adherens Assembly Nucleic Acid Metabolic Process Negative Regulation Of DNA Recombination At Telomere Primary Adaptive Immune Response
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?