DDI1 and TEKT3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DDI1	TEKT3
Description		DDI proteasomal shuttling factor 1	tektin 3
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GO Annotations	Cellular Component		Acrosomal Vesicle Acrosomal Membrane Outer Acrosomal Membrane Nucleus Cytoplasm Cytoskeleton Axonemal Microtubule Cilium Microtubule Cytoskeleton Membrane Cytoplasmic Vesicle Motile Cilium Sperm Flagellum Cell Projection Extracellular Exosome Axonemal A Tubule Inner Sheath
	Molecular Function	Aspartic-type Endopeptidase Activity Protein Binding Peptidase Activity Hydrolase Activity	Protein Binding
	Biological Process	Proteolysis Proteasomal Protein Catabolic Process Regulation Of Protein Stability Cellular Response To Hydroxyurea Regulation Of DNA Stability	Flagellated Sperm Motility Cilium Assembly Cilium Movement Involved In Cell Motility Regulation Of Brood Size
Pathways
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)	Preterm birth (maternal effect) ( 28877031) Resting heart rate ( 27798624)
Interacting Genes		18 interacting genes: ADRM1 CCL28 CYGB DVL2 FAM161B GPANK1 GSK3A KLHL42 MFHAS1 NCCRP1 RALGAPA2 RPP25 SDS TEKT3 TRAF2 UBC UBE2K USP2	33 interacting genes: AJUBA ARID5A ASPG ATN1 CALCOCO2 CNOT2 DDI1 GORASP2 HNRNPH1 IKZF3 INSC KRT34 KRTAP15-1 KRTAP19-5 KRTAP26-1 KRTAP3-1 KRTAP6-1 KRTAP6-2 KRTAP8-1 LASP1 LMO2 METTL27 OIP5 PLAGL2 PLEKHG4 RAMAC RFX6 SAXO5 SPAG8 TNS2 TRAF2 TRIB3 WWOX
Entrez ID		414301	64518
HPRD ID		13128	18173
Ensembl ID		ENSG00000170967	ENSG00000125409
Uniprot IDs		Q8WTU0	Q9BXF9
PDB IDs		3S8I	7UNG
Enriched GO Terms of Interacting Partners?		Modification-dependent Protein Catabolic Process Ubiquitin Protein Ligase Binding Proteolysis Involved In Protein Catabolic Process Macromolecule Catabolic Process Catabolic Process Proteolysis Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Ubiquitin-dependent Protein Catabolic Process Protein Catabolic Process Regulation Of JNK Cascade Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of UDP-glucose Catabolic Process TORC2 Complex Disassembly Regulation Of Brood Size Outer Acrosomal Membrane Fatty Acid Peroxidase Activity Nitric Oxide Dioxygenase Activity, Heme Protein As Donor	Intermediate Filament
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