GPANK1 and METTL27

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GPANK1	METTL27
Description		G-patch domain and ankyrin repeats 1	methyltransferase like 27
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component
	Molecular Function	Nucleic Acid Binding Protein Binding	Protein Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS		Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Febrile seizures (MMR vaccine-related) ( 25344690) Hip circumference adjusted for BMI ( 34021172) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Ulcerative colitis ( 28067908)
Interacting Genes		90 interacting genes: ABI2 AKAP8L ANAPC11 AP1B1 AP2B1 APP BAG4 C1QTNF2 CADPS CCDC184 CCDC33 CCDC85B CEACAM6 CIMIP2B CYSRT1 DDI1 DHX15 DISC1 ECM1 EFS FTO GOLGA2 GOLGA6L9 GPRASP3 GRB2 HNRNPH1 HOMEZ HSF2BP HYI INKA1 INSC KANK2 KATNBL1 KCTD9 KRT75 KRTAP10-8 KRTAP12-2 KRTAP13-3 KRTAP19-5 KRTAP19-6 LDOC1 LIG4 LZTS2 MAGED1 MAGOHB MDFI MEOX1 MEOX2 METTL27 METTL6 MID2 MORN3 NADSYN1 NFKBID NR1H3 NUTM1 OIP5 PATZ1 PAX6 PBX4 PFDN5 PLAAT1 PNMA1 PPARA PPP4C PRDM6 PTH1R RIMBP3C RTL8C SORBS3 SPATA2 STMN3 STX5 TEPSIN TFCP2 TLE5 TRAF2 TRAPPC2L TRIM23 TRIM27 TSC1 TTC19 TTC23 VBP1 VHL ZBTB16 ZBTB8OS ZMAT5 ZNF688 ZRANB1	29 interacting genes: A1CF ATXN1 ATXN1L CCDC120 CSTF2 DOK6 EFHC1 ENKD1 FOXC2 GLYCTK GPANK1 GRB2 HGS KDM1A LMO4 NOXA1 PITX1 PRKAB2 PRMT6 PROP1 SAXO4 SNRPC TBX6 TEKT3 TFG TLX3 VPS37C ZIC1 ZNF77
Entrez ID		7918	155368
HPRD ID		00810	15661
Ensembl ID		ENSG00000204438	ENSG00000165171
Uniprot IDs		A0A024RCU2 A0A0G2JHL1 A0A1U9X7R4 B2RA66 O95872	Q8N6F8
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Nucleus Regulation Of Supramolecular Fiber Organization Asymmetric Cell Division	POZ Domain Binding Axonemal A Tubule Inner Sheath Negative Regulation Of RNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of RNA Biosynthetic Process Sequence-specific Double-stranded DNA Binding Regulation Of Transcription By RNA Polymerase II Cell Fate Specification Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
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