MAP2 and TUBA1A

Number of citations of the paper that reports this interaction (PMID 18341635)
3

Data Source:
BioGRID (affinity chromatography technology, pull down)

		MAP2	TUBA1A
Gene Name		microtubule-associated protein 2	tubulin, alpha 1a
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleolus Cytoplasm Microtubule Microtubule Associated Complex Nuclear Periphery Neuronal Cell Body Dendritic Shaft	Nucleus Cytosol Microtubule Cytoplasmic Microtubule Cytoplasmic Ribonucleoprotein Granule Recycling Endosome Extracellular Vesicular Exosome
	Molecular Function	Dystroglycan Binding Structural Molecule Activity Protein Binding Calmodulin Binding Microtubule Binding	GTPase Activity Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding GTP Binding Protein Domain Specific Binding
	Biological Process	Microtubule Bundle Formation Axonogenesis Central Nervous System Neuron Development Neuron Projection Development Dendrite Morphogenesis Cellular Response To Organic Substance	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Protein Folding Organelle Organization Microtubule-based Process Cytoskeleton-dependent Intracellular Transport Cellular Protein Metabolic Process 'de Novo' Posttranslational Protein Folding Protein Polymerization Cell Division
Pathways			Transport of connexons to the plasma membrane Mitotic Prometaphase Organelle biogenesis and maintenance Axon guidance Hedgehog 'off' state Separation of Sister Chromatids Translocation of GLUT4 to the plasma membrane L1CAM interactions G2/M Transition Mitotic Anaphase Recycling pathway of L1 Recruitment of NuMA to mitotic centrosomes Regulation of PLK1 Activity at G2/M Transition Formation of tubulin folding intermediates by CCT/TriC Intraflagellar transport M Phase Prefoldin mediated transfer of substrate to CCT/TriC Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding Post-chaperonin tubulin folding pathway Loss of Nlp from mitotic centrosomes Gap junction trafficking and regulation MHC class II antigen presentation Recruitment of mitotic centrosome proteins and complexes Protein folding Gap junction assembly Gap junction trafficking Kinesins Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane Assembly of the primary cilium Factors involved in megakaryocyte development and platelet production Anchoring of the basal body to the plasma membrane Cell Cycle, Mitotic Loss of proteins required for interphase microtubule organizationÂ from the centrosome Resolution of Sister Chromatid Cohesion Chaperonin-mediated protein folding Signaling by Hedgehog Centrosome maturation Mitotic G2-G2/M phases Mitotic Metaphase and Anaphase Adaptive Immune System
Drugs		Estramustine Paclitaxel Docetaxel	Albendazole Vinblastine Mebendazole Epothilone D Epothilone B 2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE
Diseases
GWAS
Protein-Protein Interactions		24 interactors: ACTB ACTN1 APOE APP CPEB1 DAG1 FYN GRB2 GRIN1 GRIN2D JUNB MARK1 MARK3 MARK4 MYO7A NEDD4L NEFL PAFAH1B1 PLEC PRKACA PRKAR2A SRC TTBK1 TUBA1A	53 interactors: ANXA7 ARL3 ATXN3 B4GALT1 BTG1 C8orf33 CDKN1A CDKN2A CLIP1 CNP CXCR1 CYLD DAG1 DUSP23 EGFR GEMIN7 GRM7 GSK3B GZMB HTRA2 KEL KPNB1 LRRK2 MAP2 MAPK6 MAPRE1 MAX MYC NFATC1 NUDT3 PAFAH1B1 PFDN1 PLA2G7 SDC3 SIAH1 SMN1 SNCA SOCS6 SOCS7 SPG20 STARD13 SYK TAOK2 TIMM17A TK1 TLN1 TTR TUBB UBE2D3 VAV1 VCL YWHAQ ZAP70
Entrez ID		4133	7846
HPRD ID		01140	03959
Ensembl ID		ENSG00000078018	ENSG00000167552
Uniprot IDs		P11137 Q6NYC5	Q71U36
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Peptide Hormone Response To Peptide Axon Development Response To Organonitrogen Compound Nervous System Development Cellular Component Assembly Neuron Development Response To Wounding Platelet Activation Neuron Projection Development Cell Morphogenesis Involved In Neuron Differentiation Neuron Differentiation Neuromuscular Process Cell Projection Organization Movement Of Cell Or Subcellular Component Blood Coagulation Neuron Projection Morphogenesis Hemostasis Generation Of Neurons Response To Hormone Locomotion Neurogenesis Cell Morphogenesis Involved In Differentiation Axonogenesis Cell Morphogenesis Cell Development Response To Abiotic Stimulus Cellular Response To Growth Factor Stimulus Cell Projection Morphogenesis Regulation Of Body Fluid Levels Response To Growth Factor Cell Part Morphogenesis Axon Guidance Chemotaxis Wound Healing Anatomical Structure Morphogenesis Enzyme Linked Receptor Protein Signaling Pathway System Development Response To Organic Substance Transport Cell Surface Receptor Signaling Pathway Cellular Response To Peptide Hormone Stimulus Response To External Stimulus Epidermal Growth Factor Receptor Signaling Pathway Cellular Response To Peptide Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cell Differentiation Cytoskeleton Organization Multicellular Organismal Development	Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Cell Communication Cell Death Death Intracellular Signal Transduction Signaling Programmed Cell Death Response To Stimulus Response To Organic Substance Positive Regulation Of Apoptotic Process Movement Of Cell Or Subcellular Component Response To Stress Regulation Of Cellular Component Organization Negative Regulation Of Phosphorylation Apoptotic Process Developmental Process Cell Cycle Regulation Of Intracellular Transport System Development Regulation Of Intracellular Signal Transduction Defense Response Regulation Of Signal Transduction Regulation Of Signaling Cellular Response To Organic Substance Cellular Process Negative Regulation Of Intracellular Signal Transduction Locomotion Regulation Of Apoptotic Process Cellular Response To Stimulus Regulation Of Phosphorus Metabolic Process Regulation Of Protein Kinase Activity Regulation Of Immune System Process Anatomical Structure Development Signal Transduction Regulation Of Phosphorylation Regulation Of Cell Death Immune Response-regulating Signaling Pathway Neuron Development Regulation Of Growth Nervous System Development Cell Differentiation Cell Development Regulation Of Kinase Activity Neuron Projection Morphogenesis Regulation Of Cellular Process Multicellular Organismal Development Innate Immune Response Cell Projection Morphogenesis Cell Migration
Tagcloud ?		amorphous angiopathy autopsy congophilic cortices filaments frontal granular helical histologically immunolabeled immunolabeling immunolocalized map5 myelin neurofibrillary pallor plaques plastic pyramidal remarkable senile somata spongy sprouting stronger tangles temporal ultrastructurally	brainstem calorimetry elucidate exerts feeding fret interactive interacts isothermal itc library neurodegeneration neurological screened se sec selenium selenocysteines selenoprotein selenoproteins selp terminus titration trace transporter tubulin verified widespread
Tagcloud (Difference) ?		amorphous angiopathy autopsy congophilic cortices filaments frontal granular helical histologically immunolabeled immunolabeling immunolocalized map5 myelin neurofibrillary pallor plaques plastic pyramidal remarkable senile somata spongy sprouting stronger tangles temporal ultrastructurally	brainstem calorimetry elucidate exerts feeding fret interactive interacts isothermal itc library neurodegeneration neurological screened se sec selenium selenocysteines selenoprotein selenoproteins selp terminus titration trace transporter tubulin verified widespread
Tagcloud (Intersection) ?