MAP2 and MARK4

Number of citations of the paper that reports this interaction (PMID 14594945)
21

Data Source:
HPRD (in vitro)

		MAP2	MARK4
Gene Name		microtubule-associated protein 2	MAP/microtubule affinity-regulating kinase 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleolus Cytoplasm Microtubule Microtubule Associated Complex Nuclear Periphery Neuronal Cell Body Dendritic Shaft	Centrosome Microtubule Organizing Center Cytosol Microtubule Cytoskeleton Neuron Projection
	Molecular Function	Dystroglycan Binding Structural Molecule Activity Protein Binding Calmodulin Binding Microtubule Binding	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Microtubule Binding Gamma-tubulin Binding Ubiquitin Binding Tau-protein Kinase Activity
	Biological Process	Microtubule Bundle Formation Axonogenesis Central Nervous System Neuron Development Neuron Projection Development Dendrite Morphogenesis Cellular Response To Organic Substance	Microtubule Cytoskeleton Organization Microtubule Bundle Formation Protein Phosphorylation Organelle Organization Nervous System Development Positive Regulation Of Programmed Cell Death
Pathways			Organelle biogenesis and maintenance Assembly of the primary cilium Anchoring of the basal body to the plasma membrane
Drugs		Estramustine Paclitaxel Docetaxel
Diseases
GWAS
Protein-Protein Interactions		24 interactors: ACTB ACTN1 APOE APP CPEB1 DAG1 FYN GRB2 GRIN1 GRIN2D JUNB MARK1 MARK3 MARK4 MYO7A NEDD4L NEFL PAFAH1B1 PLEC PRKACA PRKAR2A SRC TTBK1 TUBA1A	28 interactors: CDC42 HGS HNRNPK HPS6 KHDRBS3 KRT31 KRT40 MAP2 MAP4 MAPT MTUS2 NEDD4 NOTCH2NL ODF2 PARD6A PNMA1 PRKCG PRKCI PRNP RPTOR STK11 TUBA4A TUBB TUBG1 UBC YWHAB YWHAH YWHAZ
Entrez ID		4133	57787
HPRD ID		01140	09402
Ensembl ID		ENSG00000078018	ENSG00000007047
Uniprot IDs		P11137 Q6NYC5	Q96L34
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Peptide Hormone Response To Peptide Axon Development Response To Organonitrogen Compound Nervous System Development Cellular Component Assembly Neuron Development Response To Wounding Platelet Activation Neuron Projection Development Cell Morphogenesis Involved In Neuron Differentiation Neuron Differentiation Neuromuscular Process Cell Projection Organization Movement Of Cell Or Subcellular Component Blood Coagulation Neuron Projection Morphogenesis Hemostasis Generation Of Neurons Response To Hormone Locomotion Neurogenesis Cell Morphogenesis Involved In Differentiation Axonogenesis Cell Morphogenesis Cell Development Response To Abiotic Stimulus Cellular Response To Growth Factor Stimulus Cell Projection Morphogenesis Regulation Of Body Fluid Levels Response To Growth Factor Cell Part Morphogenesis Axon Guidance Chemotaxis Wound Healing Anatomical Structure Morphogenesis Enzyme Linked Receptor Protein Signaling Pathway System Development Response To Organic Substance Transport Cell Surface Receptor Signaling Pathway Cellular Response To Peptide Hormone Stimulus Response To External Stimulus Epidermal Growth Factor Receptor Signaling Pathway Cellular Response To Peptide Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cell Differentiation Cytoskeleton Organization Multicellular Organismal Development	Cellular Localization G2/M Transition Of Mitotic Cell Cycle Enzyme Linked Receptor Protein Signaling Pathway Establishment Of Localization In Cell Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Golgi Localization Regulation Of Cell Projection Organization Positive Regulation Of Transport Cell Cycle Cell Cycle Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Intracellular Transport Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Neuron Development Positive Regulation Of Intracellular Transport Regulation Of Intracellular Transport Microtubule Cytoskeleton Organization Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Cellular Localization Regulation Of Cell Morphogenesis Response To Stimulus Microtubule-based Process Regulation Of Apoptotic Process Cellular Response To Organic Substance Cellular Component Assembly Establishment Of Golgi Localization Neuron Differentiation Cytoskeleton Organization Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Response To Stress Axonogenesis Regulation Of Cellular Component Organization Neuron Projection Development Negative Regulation Of ERBB Signaling Pathway Regulation Of Cell Death Generation Of Neurons Membrane Organization Axon Development Cell Morphogenesis Involved In Neuron Differentiation Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Glucocorticoid Receptor Signaling Pathway Neurogenesis
Tagcloud ?		amorphous angiopathy autopsy congophilic cortices filaments frontal granular helical histologically immunolabeled immunolabeling immunolocalized map5 myelin neurofibrillary pallor plaques plastic pyramidal remarkable senile somata spongy sprouting stronger tangles temporal ultrastructurally	acetate activator antimetastatic ap atra benzamido benzoic bis consequently cytotoxicity derivative includes interfering inverted l5 metalloproteinase mmp noncytotoxic partly plasminogen proteolytic question tac tetradecanoylphorbol tpa trimethylsilyl urokinase zymographic
Tagcloud (Difference) ?		amorphous angiopathy autopsy congophilic cortices filaments frontal granular helical histologically immunolabeled immunolabeling immunolocalized map5 myelin neurofibrillary pallor plaques plastic pyramidal remarkable senile somata spongy sprouting stronger tangles temporal ultrastructurally	acetate activator antimetastatic ap atra benzamido benzoic bis consequently cytotoxicity derivative includes interfering inverted l5 metalloproteinase mmp noncytotoxic partly plasminogen proteolytic question tac tetradecanoylphorbol tpa trimethylsilyl urokinase zymographic
Tagcloud (Intersection) ?