ARID3A and TIMM8A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ARID3A	TIMM8A
Description		AT-rich interaction domain 3A	translocase of inner mitochondrial membrane 8A
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Raft	Mitochondrion Mitochondrial Envelope Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Membrane Mitochondrial Intermembrane Space Chaperone Complex
	Molecular Function	DNA Binding Chromatin Binding Transcription Coregulator Activity Protein Binding Identical Protein Binding	Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II	Protein Targeting To Mitochondrion Nervous System Development Protein Transport Protein Insertion Into Mitochondrial Inner Membrane
Pathways		TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest	Mitochondrial protein import
Drugs
Diseases			Mohr-Tranebjaerg syndrome
GWAS		High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 27863252 32888494) Primary biliary cholangitis ( 28425483) Systemic lupus erythematosus ( 28714469) Vertical cup-disc ratio ( 20548946)
Interacting Genes		21 interacting genes: ANKRD11 APP BTK DSP E2F1 E2F2 E2F4 KRT31 MAGEB2 MAGEB4 MORF4L1 MORF4L2 NOTCH2NLA PML REP15 SP100 TIMM8A TP53 TTC32 UBE2E3 XPA	8 interacting genes: ARID3A C1QTNF2 CAVIN3 KRT15 OIP5 STAM STAM2 TIMM13
Entrez ID		1820	1678
HPRD ID		10343	02287
Ensembl ID		ENSG00000116017	ENSG00000126953
Uniprot IDs		Q99856	A0A2R8YDA8 O60220
PDB IDs		2KK0 4LJX
Enriched GO Terms of Interacting Partners?		Signal Transduction By P53 Class Mediator Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Apoptotic Signaling Pathway Intrinsic Apoptotic Signaling Pathway Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of RNA Biosynthetic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Lens Fiber Cell Apoptotic Process Rb-E2F Complex Positive Regulation Of RNA Metabolic Process DNA Damage Response DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of RNA Metabolic Process Signal Transduction In Response To DNA Damage Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Protein Dimerization Activity Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Biosynthetic Process Cis-regulatory Region Sequence-specific DNA Binding Type II Interferon-mediated Signaling Pathway Regulation Of Gene Expression Regulation Of Apoptotic Process Regulation Of Cell Cycle Transcription Regulator Complex Regulation Of Fibroblast Proliferation Regulation Of Programmed Cell Death Regulation Of Macromolecule Biosynthetic Process Nucleus Negative Regulation Of Telomere Maintenance Via Telomerase PML Body Cellular Response To Stress Retinoic Acid Receptor Signaling Pathway Entrainment Of Circadian Clock By Photoperiod Regulation Of Cellular Response To Stress DNA-binding Transcription Activator Activity Positive Regulation Of Macromolecule Metabolic Process Molecular Function Activator Activity Maintenance Of Protein Location In Nucleus Positive Regulation Of Transcription By RNA Polymerase II NuA4 Histone Acetyltransferase Complex Apoptotic Process Response To Light Stimulus RNA Polymerase II Transcription Regulator Complex Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Photoperiodism Entrainment Of Circadian Clock Negative Regulation Of RNA Biosynthetic Process	ESCRT-0 Complex Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Multivesicular Body Organization Late Endosome To Vacuole Transport Endosome Transport Via Multivesicular Body Sorting Pathway Membrane Fission Multivesicular Body Sorting Pathway Establishment Of Protein Localization To Vacuole Organelle Organization Establishment Of Protein Localization To Organelle Endosome Organization Protein Localization To Vacuole Ubiquitin Binding Phosphatidylinositol Binding Pericentric Heterochromatin Organization CENP-A Recruiting Complex Negative Regulation Of Fermentation
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