M6PR and PLIN3

Number of citations of the paper that reports this interaction (PMID 9590177)
86

Data Source:
BioGRID (pull down, two hybrid)
HPRD (two hybrid, in vitro)

		M6PR	PLIN3
Gene Name		mannose-6-phosphate receptor (cation dependent)	perilipin 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Lysosomal Membrane Endosome Late Endosome Integral Component Of Plasma Membrane Membrane Perinuclear Region Of Cytoplasm	Cytoplasm Endosome Golgi Apparatus Lipid Particle Endosome Membrane Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Transmembrane Signaling Receptor Activity Mannose Binding Mannose Transmembrane Transporter Activity	Protein Binding
	Biological Process	Receptor-mediated Endocytosis Signal Transduction Endosome To Lysosome Transport Mannose Transport	Vesicle-mediated Transport
Pathways		trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding Lysosome Vesicle Biogenesis
Drugs			Idursulfase Galsulfase
Diseases
GWAS
Protein-Protein Interactions		6 interactors: GGA1 GGA2 GGA3 JUN PLIN3 REN	9 interactors: APP CMTM5 IGF2R M6PR MAX RAB9A SMAD2 SPG20 TBPL1
Entrez ID		4074	10226
HPRD ID		01106	04080
Ensembl ID		ENSG00000003056	ENSG00000105355
Uniprot IDs		P20645	O60664
PDB IDs		1JUQ
Enriched GO Terms of Interacting Partners?		Intracellular Protein Transport Cellular Protein Localization Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Intracellular Transport Cellular Response To Potassium Ion Starvation Response To CAMP Leading Edge Cell Differentiation Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Protein Localization Response To Organophosphorus Establishment Of Localization In Cell Response To Purine-containing Compound Regulation Of Protein Metabolic Process Renin-angiotensin Regulation Of Aldosterone Production Positive Regulation Of Protein Catabolic Process Cellular Localization Positive Regulation Of Monocyte Differentiation Drinking Behavior Response To CGMP Transport SMAD Protein Import Into Nucleus Positive Regulation By Host Of Viral Transcription Response To Lipopolysaccharide Negative Regulation By Host Of Viral Transcription Angiotensin Maturation Response To Molecule Of Bacterial Origin Regulation Of Angiotensin Metabolic Process Negative Regulation Of Protein Autophosphorylation Regulation Of Blood Volume By Renin-angiotensin Microglial Cell Activation Regulation Of Systemic Arterial Blood Pressure By Circulatory Renin-angiotensin Regulation Of Monocyte Differentiation Regulation Of Protein Catabolic Process Monocyte Differentiation Negative Regulation Of Viral Transcription Beta-amyloid Metabolic Process Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin Response To Immobilization Stress Response To Bacterium Response To Drug Negative Regulation Of Neuroblast Proliferation	Negative Regulation Of Cell Differentiation Neuron Apoptotic Process Neuron Death Negative Regulation Of Collateral Sprouting In Absence Of Injury Mannose Transport Regulation Of BMP Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Synaptic Growth At Neuromuscular Junction Neuromuscular Process Collateral Sprouting In Absence Of Injury Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Zygotic Specification Of Dorsal/ventral Axis Post-embryonic Development Vesicle-mediated Transport DTTP Biosynthetic Process Endocytosis Regulation Of Cell Differentiation Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Cellular Process Abscission Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Mesoderm Development Primary MiRNA Processing Negative Regulation Of Neuron Differentiation Negative Regulation Of Collateral Sprouting Axon Choice Point Recognition Regulation Of Nodal Signaling Pathway Common-partner SMAD Protein Phosphorylation Organ Development Endosomal Transport Sexual Reproduction Positive Regulation Of Activin Receptor Signaling Pathway DNA-templated Transcription, Initiation Regulation Of Cell Development Transcription From RNA Polymerase II Promoter Neuron Remodeling Anatomical Structure Development Cellular Component Assembly Regulation Of Binding Establishment Of Localization In Cell SMAD Protein Complex Assembly Developmental Growth Deoxyribonucleotide Biosynthetic Process Regulation Of Developmental Growth Negative Regulation Of Neurogenesis Paraxial Mesoderm Morphogenesis Acrosome Assembly Lipid Particle Organization
Tagcloud ?		cathepsin compartment degraded dissociates distributed en endocytic endosome enriched fuse golgi hep internalized leaves lysosome lysosomes multivesicular mvb mvbs prelysosomal prelysosome pulse return route routed steady trans vacuolar vacuoles
Tagcloud (Difference) ?		cathepsin compartment degraded dissociates distributed en endocytic endosome enriched fuse golgi hep internalized leaves lysosome lysosomes multivesicular mvb mvbs prelysosomal prelysosome pulse return route routed steady trans vacuolar vacuoles
Tagcloud (Intersection) ?