PLIN3 and IGF2R

Number of citations of the paper that reports this interaction (PMID 9590177)
86

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		PLIN3	IGF2R
Gene Name		perilipin 3	insulin-like growth factor 2 receptor
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Endosome Golgi Apparatus Lipid Particle Endosome Membrane Membrane Intracellular Membrane-bounded Organelle	Extracellular Space Nuclear Envelope Lumen Lysosomal Membrane Endosome Late Endosome Trans-Golgi Network Integral Component Of Plasma Membrane Focal Adhesion Cell Surface Membrane Clathrin Coat Endocytic Vesicle Trans-Golgi Network Transport Vesicle Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Glycoprotein Binding G-protein Alpha-subunit Binding Retinoic Acid Binding Receptor Activity G-protein Coupled Receptor Activity Insulin-like Growth Factor-activated Receptor Activity Transporter Activity Protein Binding Mannose Binding Enzyme Binding Insulin-like Growth Factor II Binding Identical Protein Binding Phosphoprotein Binding
	Biological Process	Vesicle-mediated Transport	Liver Development Receptor-mediated Endocytosis Signal Transduction G-protein Coupled Receptor Signaling Pathway Spermatogenesis Post-embryonic Development Organ Regeneration Response To Retinoic Acid Positive Regulation Of Apoptotic Process Insulin-like Growth Factor Receptor Signaling Pathway
Pathways			Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs		Idursulfase Galsulfase
Diseases
GWAS			Brain lesion load ( 19010793)
Protein-Protein Interactions		9 interactors: APP CMTM5 IGF2R M6PR MAX RAB9A SMAD2 SPG20 TBPL1	14 interactors: AGA ATXN1 CREG1 CSNK2A1 CTSD GGA1 GGA2 GGA3 GZMB IGF2 PACS1 PLAU PLAUR PLIN3
Entrez ID		10226	3482
HPRD ID		04080	00928
Ensembl ID		ENSG00000105355	ENSG00000197081
Uniprot IDs		O60664	P11717
PDB IDs			1E6F 1GP0 1GP3 1GQB 1JPL 1JWG 1LF8 2CNJ 2L29 2L2A 2V5N 2V5O 2V5P
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cell Differentiation Neuron Apoptotic Process Neuron Death Negative Regulation Of Collateral Sprouting In Absence Of Injury Mannose Transport Regulation Of BMP Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Synaptic Growth At Neuromuscular Junction Neuromuscular Process Collateral Sprouting In Absence Of Injury Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Zygotic Specification Of Dorsal/ventral Axis Post-embryonic Development Vesicle-mediated Transport DTTP Biosynthetic Process Endocytosis Regulation Of Cell Differentiation Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Cellular Process Abscission Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Mesoderm Development Primary MiRNA Processing Negative Regulation Of Neuron Differentiation Negative Regulation Of Collateral Sprouting Axon Choice Point Recognition Regulation Of Nodal Signaling Pathway Common-partner SMAD Protein Phosphorylation Organ Development Endosomal Transport Sexual Reproduction Positive Regulation Of Activin Receptor Signaling Pathway DNA-templated Transcription, Initiation Regulation Of Cell Development Transcription From RNA Polymerase II Promoter Neuron Remodeling Anatomical Structure Development Cellular Component Assembly Regulation Of Binding Establishment Of Localization In Cell SMAD Protein Complex Assembly Developmental Growth Deoxyribonucleotide Biosynthetic Process Regulation Of Developmental Growth Negative Regulation Of Neurogenesis Paraxial Mesoderm Morphogenesis Acrosome Assembly Lipid Particle Organization	Vesicle-mediated Transport Fibrinolysis Positive Regulation Of Protein Catabolic Process Negative Regulation Of Blood Coagulation Establishment Of Localization In Cell Negative Regulation Of Coagulation Urokinase Plasminogen Activator Signaling Pathway Negative Regulation Of Wound Healing Intracellular Transport Regulation Of Protein Catabolic Process Intracellular Protein Transport Cellular Localization Regulation Of Blood Coagulation Blood Coagulation Regulation Of Smooth Muscle Cell-matrix Adhesion Hemostasis Regulation Of Receptor Activity Protein Deglycosylation Insulin Receptor Signaling Pathway Via Phosphatidylinositol 3-kinase Regulation Of Mitotic Nuclear Division Regulation Of Wound Healing Positive Regulation Of Glycogen (starch) Synthase Activity Granzyme-mediated Apoptotic Signaling Pathway
Tagcloud ?			acting base box constitutes copies differentially discrimination distinguish dmr dmrs embryo encodes erased establishment germ gonads imprint imprinted imprinting includes maintained mark methylated methylation novo pair parent paternal phenomenon
Tagcloud (Difference) ?			acting base box constitutes copies differentially discrimination distinguish dmr dmrs embryo encodes erased establishment germ gonads imprint imprinted imprinting includes maintained mark methylated methylation novo pair parent paternal phenomenon
Tagcloud (Intersection) ?