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PLIN3 and M6PR
Number of citations of the paper that reports this interaction (PMID
9590177
)
86
Data Source:
BioGRID
(pull down, two hybrid)
HPRD
(two hybrid, in vitro)
PLIN3
M6PR
Gene Name
perilipin 3
mannose-6-phosphate receptor (cation dependent)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Endosome
Golgi Apparatus
Lipid Particle
Endosome Membrane
Membrane
Intracellular Membrane-bounded Organelle
Lysosomal Membrane
Endosome
Late Endosome
Integral Component Of Plasma Membrane
Membrane
Perinuclear Region Of Cytoplasm
Molecular Function
Protein Binding
Transmembrane Signaling Receptor Activity
Mannose Binding
Mannose Transmembrane Transporter Activity
Biological Process
Vesicle-mediated Transport
Receptor-mediated Endocytosis
Signal Transduction
Endosome To Lysosome Transport
Mannose Transport
Pathways
trans-Golgi Network Vesicle Budding
Clathrin derived vesicle budding
Lysosome Vesicle Biogenesis
Drugs
Idursulfase
Galsulfase
Diseases
GWAS
Protein-Protein Interactions
9 interactors:
APP
CMTM5
IGF2R
M6PR
MAX
RAB9A
SMAD2
SPG20
TBPL1
6 interactors:
GGA1
GGA2
GGA3
JUN
PLIN3
REN
Entrez ID
10226
4074
HPRD ID
04080
01106
Ensembl ID
ENSG00000105355
ENSG00000003056
Uniprot IDs
O60664
P20645
PDB IDs
1JUQ
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Cell Differentiation
Neuron Apoptotic Process
Neuron Death
Negative Regulation Of Collateral Sprouting In Absence Of Injury
Mannose Transport
Regulation Of BMP Signaling Pathway
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Positive Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry
Synaptic Growth At Neuromuscular Junction
Neuromuscular Process
Collateral Sprouting In Absence Of Injury
Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry
Zygotic Specification Of Dorsal/ventral Axis
Post-embryonic Development
Vesicle-mediated Transport
DTTP Biosynthetic Process
Endocytosis
Regulation Of Cell Differentiation
Collateral Sprouting
Axon Midline Choice Point Recognition
Regulation Of Cellular Process
Abscission
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Positive Regulation Of Mesoderm Development
Primary MiRNA Processing
Negative Regulation Of Neuron Differentiation
Negative Regulation Of Collateral Sprouting
Axon Choice Point Recognition
Regulation Of Nodal Signaling Pathway
Common-partner SMAD Protein Phosphorylation
Organ Development
Endosomal Transport
Sexual Reproduction
Positive Regulation Of Activin Receptor Signaling Pathway
DNA-templated Transcription, Initiation
Regulation Of Cell Development
Transcription From RNA Polymerase II Promoter
Neuron Remodeling
Anatomical Structure Development
Cellular Component Assembly
Regulation Of Binding
Establishment Of Localization In Cell
SMAD Protein Complex Assembly
Developmental Growth
Deoxyribonucleotide Biosynthetic Process
Regulation Of Developmental Growth
Negative Regulation Of Neurogenesis
Paraxial Mesoderm Morphogenesis
Acrosome Assembly
Lipid Particle Organization
Intracellular Protein Transport
Cellular Protein Localization
Protein Transport
Vesicle-mediated Transport
Establishment Of Protein Localization
Intracellular Transport
Cellular Response To Potassium Ion Starvation
Response To CAMP
Leading Edge Cell Differentiation
Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress
Protein Localization
Response To Organophosphorus
Establishment Of Localization In Cell
Response To Purine-containing Compound
Regulation Of Protein Metabolic Process
Renin-angiotensin Regulation Of Aldosterone Production
Positive Regulation Of Protein Catabolic Process
Cellular Localization
Positive Regulation Of Monocyte Differentiation
Drinking Behavior
Response To CGMP
Transport
SMAD Protein Import Into Nucleus
Positive Regulation By Host Of Viral Transcription
Response To Lipopolysaccharide
Negative Regulation By Host Of Viral Transcription
Angiotensin Maturation
Response To Molecule Of Bacterial Origin
Regulation Of Angiotensin Metabolic Process
Negative Regulation Of Protein Autophosphorylation
Regulation Of Blood Volume By Renin-angiotensin
Microglial Cell Activation
Regulation Of Systemic Arterial Blood Pressure By Circulatory Renin-angiotensin
Regulation Of Monocyte Differentiation
Regulation Of Protein Catabolic Process
Monocyte Differentiation
Negative Regulation Of Viral Transcription
Beta-amyloid Metabolic Process
Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin
Response To Immobilization Stress
Response To Bacterium
Response To Drug
Negative Regulation Of Neuroblast Proliferation
Tagcloud
?
cathepsin
compartment
degraded
dissociates
distributed
en
endocytic
endosome
enriched
fuse
golgi
hep
internalized
leaves
lysosome
lysosomes
multivesicular
mvb
mvbs
prelysosomal
prelysosome
pulse
return
route
routed
steady
trans
vacuolar
vacuoles
Tagcloud (Difference)
?
cathepsin
compartment
degraded
dissociates
distributed
en
endocytic
endosome
enriched
fuse
golgi
hep
internalized
leaves
lysosome
lysosomes
multivesicular
mvb
mvbs
prelysosomal
prelysosome
pulse
return
route
routed
steady
trans
vacuolar
vacuoles
Tagcloud (Intersection)
?