PLIN3 and CHMP4B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PLIN3	CHMP4B
Description		perilipin 3	charged multivesicular body protein 4B
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endosome Golgi Apparatus Lipid Droplet Cytosol Endosome Membrane Membrane Transport Vesicle	Autophagosome Membrane Kinetochore ESCRT III Complex Nucleus Nuclear Envelope Nuclear Pore Cytoplasm Lysosomal Membrane Endosome Multivesicular Body Kinetochore Microtubule Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Membrane Membrane Coat Midbody Late Endosome Membrane Vesicle Multivesicular Body Membrane Extracellular Exosome Amphisome Membrane
	Molecular Function	Protein Binding Cadherin Binding	Protein Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding
	Biological Process	Positive Regulation Of Triglyceride Storage Vesicle-mediated Transport Lipid Storage Cellular Response To Glucose Starvation Lipid Droplet Disassembly	Mitotic Cytokinesis Plasma Membrane Repair Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Vesicle Budding From Membrane Autophagy Nucleus Organization Vacuolar Transport Mitotic Metaphase Chromosome Alignment Exit From Mitosis Regulation Of Centrosome Duplication Protein Transport Macroautophagy Nuclear Membrane Reassembly Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Maintenance Of Lens Transparency Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Viral Budding Viral Budding From Plasma Membrane Nervous System Process Protein Polymerization Vesicle Fusion With Vacuole Multivesicular Body-lysosome Fusion Midbody Abscission Multivesicular Body Sorting Pathway Membrane Fission Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Autophagosome Maturation Regulation Of Mitotic Spindle Assembly Late Endosome To Lysosome Transport
Pathways		Triglyceride catabolism Retrograde transport at the Trans-Golgi-Network Lipophagy Chaperone Mediated Autophagy Late endosomal microautophagy RHOBTB3 ATPase cycle	Budding and maturation of HIV virion Macroautophagy Pyroptosis Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex
Drugs		Idursulfase Galsulfase
Diseases
GWAS		Basal cell carcinoma ( 27539887) Lung cancer in ever smokers ( 28604730) Visceral fat ( 30942860)	Feeling nervous ( 29500382) Loneliness ( 27629369) Offspring birth weight ( 31043758) Refractive error ( 32231278) Stearic acid (18:0) levels ( 23362303)
Interacting Genes		33 interacting genes: ABHD4 ABHD5 APP CCNC CEBPA CHMP4B CMTM5 CPD CYBC1 GAD2 HSD17B13 IGF2R LNPK M6PR MAX MIEF1 MYG1 PBX3 PIAS3 PTPN9 RAB9A SFT2D2 SMAD2 SNX1 SNX2 SPART SYNGR1 SYNGR3 SYP TARS2 TBC1D13 TBPL1 TMEM14C	18 interacting genes: CEBPA CHMP1B CHMP3 CHMP4A CHMP4C CHMP5 CHMP6 EXOSC9 HIPK2 NOD2 PDCD6IP PIAS2 PLIN3 PTPN23 SNCA STAMBP UBE2I VPS4A
Entrez ID		10226	128866
HPRD ID		04080	16642
Ensembl ID		ENSG00000105355	ENSG00000101421
Uniprot IDs		A0A140VJN8 O60664	Q9H444
PDB IDs			3C3Q 3UM3 4ABM 5MK2
Enriched GO Terms of Interacting Partners?		Collateral Sprouting In Absence Of Injury Insulin Receptor Binding Regulation Of Long-term Neuronal Synaptic Plasticity Vesicle-mediated Transport Identical Protein Binding Retromer, Tubulation Complex Leptin Receptor Binding Lipid Droplet Trans-Golgi Network Membrane Lamellipodium Morphogenesis Regulation Of Neuronal Synaptic Plasticity Endocytosis Nuclear Envelope Lumen Retromer Complex Binding Transferrin Receptor Binding Regulation Of Synaptic Vesicle Priming Lysophosphatidic Acid Acyltransferase Activity Intracellular Transport Receptor-mediated Endocytosis Regulation Of Short-term Neuronal Synaptic Plasticity Synaptic Vesicle Membrane Organization Collateral Sprouting Early Endosome To Golgi Transport Neuromuscular Junction Endosome Establishment Of Protein Localization Neuron Projection Terminus Regulation Of Neurotransmitter Uptake Retromer Complex Protein Transport Retrograde Transport, Endosome To Golgi Midbody Abscission Transport Vesicle Cytoplasmic Vesicle Import Into Cell Mitotic Cytokinetic Process	Viral Budding Via Host ESCRT Complex Midbody Abscission Nuclear Membrane Reassembly Viral Budding Mitotic Cytokinetic Process Viral Budding From Plasma Membrane Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Multivesicular Body Assembly Multivesicular Body Organization Late Endosome To Vacuole Transport Cytokinetic Process Late Endosome To Lysosome Transport Endosome Transport Via Multivesicular Body Sorting Pathway Mitotic Metaphase Chromosome Alignment Regulation Of Mitotic Spindle Assembly Multivesicular Body Sorting Pathway Nucleus Organization Nuclear Membrane Organization ESCRT III Complex Amphisome Membrane Vesicle Fusion With Vacuole Membrane Assembly Metaphase Chromosome Alignment Viral Release From Host Cell Multivesicular Body-lysosome Fusion Plasma Membrane Repair Regulation Of Spindle Assembly Lysosomal Membrane Organization Chromosome Localization Endosome Organization Regulation Of Mitotic Spindle Organization Nuclear Pore Membrane Fission Kinetochore Microtubule Autophagosome Maturation Multivesicular Body Membrane Viral Process Regulation Of Microtubule Cytoskeleton Organization Vacuolar Transport Multivesicular Body Vesicle Fusion Autophagy Organelle Membrane Fusion Autophagosome Membrane Plasma Membrane Organization Lysosomal Transport Endosome Organelle Fusion Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Protein-containing Complex Disassembly
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