M6PR

Gene Name		mannose-6-phosphate receptor (cation dependent)
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Gene Ontology Annotations	Cellular Component	Lysosomal Membrane Endosome Late Endosome Integral Component Of Plasma Membrane Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Transmembrane Signaling Receptor Activity Mannose Binding Mannose Transmembrane Transporter Activity
	Biological Process	Receptor-mediated Endocytosis Signal Transduction Endosome To Lysosome Transport Mannose Transport
Pathways		trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding Lysosome Vesicle Biogenesis
Drugs
Diseases
GWAS
Protein-protein Interactions		6 interactors: GGA1 GGA2 GGA3 JUN PLIN3 REN
Entrez ID		4074
HPRD ID		01106
Ensembl ID		ENSG00000003056
Uniprot IDs		P20645
PDB IDs		1JUQ
Enriched GO Terms of Interacting Partners?		Intracellular Protein Transport Cellular Protein Localization Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Intracellular Transport Cellular Response To Potassium Ion Starvation Response To CAMP Leading Edge Cell Differentiation Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Protein Localization Response To Organophosphorus Establishment Of Localization In Cell Response To Purine-containing Compound Regulation Of Protein Metabolic Process Renin-angiotensin Regulation Of Aldosterone Production Positive Regulation Of Protein Catabolic Process Cellular Localization Positive Regulation Of Monocyte Differentiation Drinking Behavior Response To CGMP Transport SMAD Protein Import Into Nucleus Positive Regulation By Host Of Viral Transcription Response To Lipopolysaccharide Negative Regulation By Host Of Viral Transcription Angiotensin Maturation Response To Molecule Of Bacterial Origin Regulation Of Angiotensin Metabolic Process Negative Regulation Of Protein Autophosphorylation Regulation Of Blood Volume By Renin-angiotensin Microglial Cell Activation Regulation Of Systemic Arterial Blood Pressure By Circulatory Renin-angiotensin Regulation Of Monocyte Differentiation Regulation Of Protein Catabolic Process Monocyte Differentiation Negative Regulation Of Viral Transcription Beta-amyloid Metabolic Process Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin Response To Immobilization Stress Response To Bacterium Response To Drug Negative Regulation Of Neuroblast Proliferation
Tagcloud ?		cathepsin compartment degraded dissociates distributed en endocytic endosome enriched fuse golgi hep internalized leaves lysosome lysosomes multivesicular mvb mvbs prelysosomal prelysosome pulse return route routed steady trans vacuolar vacuoles