MIR106B and CHERP

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		MIR106B	CHERP
Description		microRNA 106b	calcium homeostasis endoplasmic reticulum protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space RISC Complex Extracellular Vesicle	Nucleoplasm Cytoplasm Endoplasmic Reticulum Membrane Sarcoplasmic Reticulum Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	MRNA 3'-UTR Binding MRNA Base-pairing Post-transcriptional Repressor Activity	Nucleic Acid Binding RNA Binding Protein Binding Transmembrane Transporter Binding
	Biological Process	Negative Regulation Of Gene Expression Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Angiogenesis Negative Regulation Of Interleukin-8 Production MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By Inhibition Of Translation MiRNA-mediated Gene Silencing By MRNA Destabilization Cellular Response To Hypoxia Cellular Response To Amyloid-beta Regulation Of Endothelial Cell Apoptotic Process	RNA Processing Intracellular Calcium Ion Homeostasis Nervous System Development Negative Regulation Of Cell Population Proliferation Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Calcineurin-NFAT Signaling Cascade
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Interacting Genes		97 interacting genes: AIMP1 AQR C1QBP CCAR1 CDC40 CDC5L CELF1 CHERP CPSF1 DARS1 DDX1 DDX21 DDX23 DDX3X DDX3Y DHX36 DHX37 EDC4 EIF2AK2 EPRS1 ERAL1 ESRP1 FUS G3BP2 GRSF1 HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 NOL6 NONO NUDT21 NUFIP2 PDCD11 PGAM5 PLRG1 PRMT1 PTBP1 PTBP3 PUF60 PUM1 PURA QARS1 RARS1 RBM10 RBM14 RBM17 RBM4 RTCA RTCB SF1 SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 SUGP2 SYNCRIP TAF15 TIAL1 TRA2A TRA2B U2SURP UPF1 UTP20 XAB2 YBX1 YBX2 YBX3 ZFR ZNF346	48 interacting genes: ADAMTSL4 AGGF1 APBB1 ARGLU1 C1orf94 CCAR1 CLK3 EWSR1 FASTK FIGN FRA10AC1 HNRNPH3 KRTAP11-1 LASP1 LUC7L MAGED1 MECOM MIR106B MIR200C MIR363 MIRLET7A2 MIRLET7C MIRLET7D MIRLET7E MIRLET7G MIRLET7I PPIL4 PRPF38A PRPF40A RACK1 RBFOX2 RBM23 RBM39 RBM7 RNPS1 SART1 SAXO1 SF3B4 SNRNP27 SNRNP70 SORBS3 SRPK1 SRPK2 TLE3 TTC14 U2AF1 USP54 WBP4
Entrez ID		406900	10523
HPRD ID			13051
Ensembl ID		ENSG00000208036	ENSG00000085872
Uniprot IDs			Q8IWX8
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process RNA Splicing MRNA Processing MRNA Metabolic Process Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Binding Spliceosomal Complex Catalytic Step 2 Spliceosome Nucleoplasm Macromolecule Metabolic Process Regulation Of RNA Splicing Regulation Of MRNA Metabolic Process Nucleus Post-transcriptional Regulation Of Gene Expression Aminoacyl-tRNA Synthetase Multienzyme Complex Ribonucleoprotein Complex Cytoplasmic Stress Granule MiRNA Binding Negative Regulation Of MRNA Metabolic Process MRNA 3'-UTR Binding Regulation Of MRNA Processing Regulation Of Translation Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Catabolic Process TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity Negative Regulation Of MRNA Catabolic Process Regulation Of RNA Stability RNA Stabilization TRNA Aminoacylation Negative Regulation Of Translation MRNA Stabilization Regulation Of MRNA Stability Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Protein-RNA Complex Assembly Ligase Activity U2 SnRNP Spliceosomal Complex Assembly RNA Helicase Activity Nucleolus Positive Regulation Of Cytoplasmic Translation TRNA Metabolic Process Regulation Of Macromolecule Metabolic Process	RNA Splicing MRNA Processing Regulation Of RNA Splicing Regulation Of MRNA Metabolic Process MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Processing RNA Splicing, Via Transesterification Reactions RNA Binding Regulation Of MRNA Splicing, Via Spliceosome MiRNA-mediated Post-transcriptional Gene Silencing Nucleic Acid Binding Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Nuclear Speck Regulation Of MRNA Processing RISC Complex Post-transcriptional Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Regulatory NcRNA-mediated Gene Silencing RNA Metabolic Process Spliceosomal Complex RS Domain Binding U1 SnRNP Binding Post-transcriptional Regulation Of Gene Expression Regulation Of Gene Expression MiRNA-mediated Gene Silencing By MRNA Destabilization Regulation Of Macromolecule Biosynthetic Process Nucleic Acid Metabolic Process MRNA Cis Splicing, Via Spliceosome U2-type Precatalytic Spliceosome U2-type Prespliceosome Negative Regulation Of Macromolecule Biosynthetic Process U1 SnRNP Precatalytic Spliceosome Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of MRNA Metabolic Process Nucleoplasm Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Negative Regulation Of Interleukin-6-mediated Signaling Pathway Extracellular Vesicle Nucleobase-containing Compound Metabolic Process MRNA Destabilization RNA Destabilization Regulation Of MRNA Stability Regulation Of RNA Metabolic Process Protein-RNA Complex Assembly Negative Regulation Of Gene Expression
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