ARNT2 and FAAP20

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ARNT2	FAAP20
Description		aryl hydrocarbon receptor nuclear translocator 2	FA core complex associated protein 20
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm Aryl Hydrocarbon Receptor Complex	Chromatin Nucleus Nucleoplasm Chromosome Cytosol Nuclear Body Cell Junction Fanconi Anaemia Nuclear Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Aryl Hydrocarbon Receptor Binding Protein-containing Complex Binding Protein Heterodimerization Activity Protein Dimerization Activity Sequence-specific Double-stranded DNA Binding	Protein Binding Zinc Ion Binding Polyubiquitin Modification-dependent Protein Binding Ubiquitin Binding Metal Ion Binding K63-linked Polyubiquitin Modification-dependent Protein Binding Ubiquitin-modified Protein Reader Activity
	Biological Process	Response To Hypoxia In Utero Embryonic Development Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Brain Development Positive Regulation Of Cell Population Proliferation Response To Estradiol Negative Regulation Of Apoptotic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II	DNA Repair DNA Damage Response Translesion Synthesis Interstrand Cross-link Repair
Pathways		PPARA activates gene expression Phase I - Functionalization of compounds Endogenous sterols Xenobiotics Aryl hydrocarbon receptor signalling NPAS4 regulates expression of target genes NPAS4 regulates expression of target genes	Fanconi Anemia Pathway PKR-mediated signaling
Drugs
Diseases
GWAS		Atrial fibrillation ( 29892015 30061737) Attention deficit hyperactivity disorder ( 29325848) Bipolar disorder ( 20351715) Body mass index ( 26426971) Gut microbiota relative abundance (unclassified genus belonging to family Erysipelotrichaceae) ( 33208821) HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245)	Sedentary behaviour duration ( 30531941) TPE interval (resting) ( 32386560)
Interacting Genes		69 interacting genes: ADAMTSL4 AHR AP1M1 AP3M1 APP ARNT CALCOCO2 CAPN7 CCDC33 CDR2 CEP57L1 CEP63 CTBP1 DGCR6 DTX2 DYDC1 EPAS1 FAAP20 GOLGA2 HIF1A IKZF3 KIFC3 LMO2 LMO4 LZTS2 MAGEA4 MAGED1 MEIS2 MEOX2 MIPOL1 MTDH MTUS2 NCOA3 NDE1 NPAS2 NPAS4 OSGIN1 PDE4DIP PLSCR1 PSMB1 RBCK1 REL RFX6 RIMBP3 RINT1 SH3GL2 SIM1 SORBS3 SPAG5 SSBP3 SSX2IP STK16 SYCE1 TACC3 TADA2A TAX1BP3 TFIP11 TRAF1 TRAF2 TRIM23 TRIM27 TRIM37 TRIM42 TRIP6 TSPOAP1 USHBP1 USP7 VPS52 ZNF341	28 interacting genes: ARNT2 BPIFA1 CRX CT55 CTDSP1 DDIT4L DUSP21 FANCF GOLGA6L9 INCA1 KRTAP6-2 KRTAP8-1 LCN2 LMO2 LRP2BP MEOX2 MOB2 NFKBID PFDN5 PIN1 PRDM5 REL REV1 SERTAD1 SERTAD3 TEX11 TRIB3 UBC
Entrez ID		9915	199990
HPRD ID		06915	08707
Ensembl ID		ENSG00000172379	ENSG00000162585
Uniprot IDs		Q86TN1 Q9HBZ2 X5DQN9	F6S8H2 Q6NZ36 Q6ZRT9 Q7Z4P6
PDB IDs			2MUQ 2MUR 3WWQ
Enriched GO Terms of Interacting Partners?		Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Protein Binding Positive Regulation Of Macromolecule Biosynthetic Process Transcription Coactivator Activity Positive Regulation Of Biosynthetic Process Transcription Regulator Complex Protein Dimerization Activity Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Metabolic Process Cytoplasm Positive Regulation Of Transcription By RNA Polymerase II RNA Polymerase II-specific DNA-binding Transcription Factor Binding Positive Regulation Of Macromolecule Metabolic Process Nuclear Aryl Hydrocarbon Receptor Complex Nucleus Microtubule Organizing Center Organization DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Centrosome Protein Heterodimerization Activity DNA-binding Transcription Factor Activity Chromatin Microtubule-based Process Positive Regulation Of Autophagy Regulation Of Primary Metabolic Process Establishment Of Localization In Cell Benzodiazepine Receptor Binding Positive Regulation Of Glycolytic Process Embryonic Placenta Development Regulation Of Macromolecule Biosynthetic Process Cytoskeleton Intracellular Transport Regulation Of Gene Expression Tumor Necrosis Factor Receptor Binding Positive Regulation Of NF-kappaB Transcription Factor Activity Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Macromolecule Metabolic Process Aryl Hydrocarbon Receptor Complex Regulation Of Metabolic Process Intestinal Epithelial Structure Maintenance Positive Regulation Of ATP Metabolic Process Microtubule RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Identical Protein Binding
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