ARNT2 and SSX2IP

Number of citations of the paper that reports this interaction (PubMedID 24722188)
69

Data Source:
BioGRID (two hybrid)

		ARNT2	SSX2IP
Description		aryl hydrocarbon receptor nuclear translocator 2	SSX family member 2 interacting protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm Aryl Hydrocarbon Receptor Complex	Nucleus Cytoplasm Centrosome Cytoskeleton Adherens Junction Cell Leading Edge Protein-containing Complex Centriolar Satellite Ciliary Basal Body Cell Projection Anchoring Junction
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Aryl Hydrocarbon Receptor Binding Protein-containing Complex Binding Protein Heterodimerization Activity Protein Dimerization Activity Sequence-specific Double-stranded DNA Binding	Protein Binding Protein Domain Specific Binding
	Biological Process	Response To Hypoxia In Utero Embryonic Development Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Brain Development Positive Regulation Of Cell Population Proliferation Response To Estradiol Negative Regulation Of Apoptotic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II	Centrosome Cycle Cell Adhesion Cell Projection Organization Regulation Of Rac Protein Signal Transduction Intraciliary Transport Involved In Cilium Assembly Cilium Assembly Regulation Of Cell Motility
Pathways		PPARA activates gene expression Phase I - Functionalization of compounds Endogenous sterols Xenobiotics Aryl hydrocarbon receptor signalling NPAS4 regulates expression of target genes NPAS4 regulates expression of target genes
Drugs
Diseases
GWAS		Atrial fibrillation ( 29892015 30061737) Attention deficit hyperactivity disorder ( 29325848) Bipolar disorder ( 20351715) Body mass index ( 26426971) Gut microbiota relative abundance (unclassified genus belonging to family Erysipelotrichaceae) ( 33208821) HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245)	Urinary albumin-to-creatinine ratio in non-diabetics ( 26631737) Waist-to-hip ratio adjusted for body mass index ( 28430825)
Interacting Genes		69 interacting genes: ADAMTSL4 AHR AP1M1 AP3M1 APP ARNT CALCOCO2 CAPN7 CCDC33 CDR2 CEP57L1 CEP63 CTBP1 DGCR6 DTX2 DYDC1 EPAS1 FAAP20 GOLGA2 HIF1A IKZF3 KIFC3 LMO2 LMO4 LZTS2 MAGEA4 MAGED1 MEIS2 MEOX2 MIPOL1 MTDH MTUS2 NCOA3 NDE1 NPAS2 NPAS4 OSGIN1 PDE4DIP PLSCR1 PSMB1 RBCK1 REL RFX6 RIMBP3 RINT1 SH3GL2 SIM1 SORBS3 SPAG5 SSBP3 SSX2IP STK16 SYCE1 TACC3 TADA2A TAX1BP3 TFIP11 TRAF1 TRAF2 TRIM23 TRIM27 TRIM37 TRIM42 TRIP6 TSPOAP1 USHBP1 USP7 VPS52 ZNF341	114 interacting genes: ABLIM3 ACTN1 ACTN2 AEN AFDN AP1M1 ARNT2 ATOSA BCL6 BEX2 BKGD BRCA1 BYSL CARD9 CCDC187 CCDC198 CCHCR1 CCNH CDC23 CDC42 CDCA7L CHCHD3 DAXX DRG1 DVL2 EAF2 EHHADH EIF4A2 ERAL1 FAM124B FAM161A FANCG FANCL FBF1 FNDC11 FRMD6 GEM GOLGA2 GOLGA8F GRAP2 HDAC4 HNRNPLL IKBKG INO80B KAT5 KDM1A KIF9 KIFC3 KLHL42 KRT15 KRT31 KRT40 KRTAP10-7 LATS1 LMO2 MCM7 MFAP1 MORN4 MOS MRPL53 NAA10 NDN NIF3L1 NOL12 NTAQ1 PHC2 PIMREG PKN1 PNMA1 POLL PRKAA1 PRKAB2 PRMT6 PRPF3 PRPF31 PSMA1 RAB1A RNF6 SCNM1 SHFL SSX2 SSX3 SYT17 TBP TEAD4 TFIP11 TOP3B TRIM42 TRIM54 TSGA10IP TSTD2 TTC23 WDR5 XIAP YWHAQ YWHAZ ZBTB24 ZFYVE26 ZGPAT ZMAT2 ZNF124 ZNF202 ZNF250 ZNF3 ZNF408 ZNF417 ZNF438 ZNF587 ZNF648 ZNF688 ZNF71 ZNF792 ZRSR2 ZSCAN12
Entrez ID		9915	117178
HPRD ID		06915	10566
Ensembl ID		ENSG00000172379	ENSG00000117155
Uniprot IDs		Q86TN1 Q9HBZ2 X5DQN9	B7ZB07 Q9Y2D8
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Protein Binding Positive Regulation Of Macromolecule Biosynthetic Process Transcription Coactivator Activity Positive Regulation Of Biosynthetic Process Transcription Regulator Complex Protein Dimerization Activity Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Metabolic Process Cytoplasm Positive Regulation Of Transcription By RNA Polymerase II RNA Polymerase II-specific DNA-binding Transcription Factor Binding Positive Regulation Of Macromolecule Metabolic Process Nuclear Aryl Hydrocarbon Receptor Complex Nucleus Microtubule Organizing Center Organization DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Centrosome Protein Heterodimerization Activity DNA-binding Transcription Factor Activity Chromatin Microtubule-based Process Positive Regulation Of Autophagy Regulation Of Primary Metabolic Process Establishment Of Localization In Cell Benzodiazepine Receptor Binding Positive Regulation Of Glycolytic Process Embryonic Placenta Development Regulation Of Macromolecule Biosynthetic Process Cytoskeleton Intracellular Transport Regulation Of Gene Expression Tumor Necrosis Factor Receptor Binding Positive Regulation Of NF-kappaB Transcription Factor Activity Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Macromolecule Metabolic Process Aryl Hydrocarbon Receptor Complex Regulation Of Metabolic Process Intestinal Epithelial Structure Maintenance Positive Regulation Of ATP Metabolic Process Microtubule RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Identical Protein Binding	Nucleus Protein Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Identical Protein Binding Regulation Of RNA Metabolic Process Regulation Of Primary Metabolic Process Zinc Ion Binding Nucleoplasm Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Transcription By RNA Polymerase II Nuclear Androgen Receptor Binding Metal Ion Binding Regulation Of Metabolic Process DNA Damage Response DNA Recombination DNA-binding Transcription Factor Binding Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Spliceosomal Complex Mitotic Spindle U2-type Precatalytic Spliceosome Keratin Filament MRNA Splicing, Via Spliceosome DNA Binding RNA Splicing, Via Transesterification Reactions Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Nucleic Acid Metabolic Process AMP-activated Protein Kinase Activity Transcription Coactivator Activity Protein K6-linked Ubiquitination
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