ARLN and PLEKHO1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ARLN	PLEKHO1
Description		allregulin	pleckstrin homology domain containing O1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Nucleus Cytoplasm Plasma Membrane Membrane Ruffle Membrane Muscle Cell Projection Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process		Myoblast Fusion Regulation Of Cell Shape Myoblast Migration Lamellipodium Morphogenesis Regulation Of Myoblast Fusion
Pathways
Drugs
Diseases
GWAS			Bipolar disorder ( 31043756) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		73 interacting genes: ADGRG3 AQP2 AQP6 ARL13B ATP2A2 BCL2L13 BIK C5AR2 CALM1 CCRL2 CD79A CISD2 CLDN9 CREB3L1 CXCR2 CYBC1 EBP ELN ELOVL4 ERGIC3 FAM174A FAM209A FFAR2 GJA5 GJB4 GJB5 GLP1R GPR61 GPX8 HHATL HTR2C JAGN1 LAPTM5 LMNA LY6G6C MILR1 MMD MMGT1 MRM3 MS4A3 NCAPH2 PLEKHO1 PLN PTGES REEP4 RETREG3 RHBDL1 RHCG SCN3B SERINC2 SHISAL1 SLC10A6 SLC14A2 SLC19A3 SLC35E3 SLC35H1 SLC39A2 SLC41A3 SLC71A2 SLCO3A1 SMO SSMEM1 STX1A SYNPR TIMMDC1 TM4SF19 TMEM101 TMEM237 TMEM248 TMEM45A TMEM45B TMEM51 YIF1A	33 interacting genes: ADAM33 AKT1 AKT2 ARLN BNIP2 BRICD5 C10orf88 CEP19 COL8A2 CSNK2A1 CYP4F2 DNAJB1 FLNB IFI35 LRP10 MMD NAPB OGT PSMC5 RPS20 SMAD5 SMURF1 THSD7B TMEM218 TNF TRAF3IP3 TRAF6 TRAM1L1 TSPAN33 TSPO2 USP7 VAMP3 ZFPL1
Entrez ID		401152	51177
HPRD ID		14223	12217
Ensembl ID		ENSG00000164096	ENSG00000023902
Uniprot IDs		Q8WVX3	Q53GL0 Q5T4P9
PDB IDs			3AA1
Enriched GO Terms of Interacting Partners?		Membrane Transmembrane Transport Protein Binding Plasma Membrane Calcium Ion-transporting ATPase Complex Endoplasmic Reticulum Membrane G Protein-coupled Receptor Activity Connexin Complex Regulation Of Heart Rate Gap Junction Channel Activity Carbon Dioxide Transmembrane Transporter Activity One-carbon Compound Transport Carbon Dioxide Transmembrane Transport Gap Junction Regulation Of Heart Contraction Regulation Of Cardiac Muscle Cell Action Potential Transporter Inhibitor Activity SA Node Cell Action Potential Transmembrane Transporter Binding Mitochondrion-endoplasmic Reticulum Membrane Tethering Regulation Of Cardiac Muscle Cell Membrane Potential Autophagosome Membrane Docking Regulation Of Cardiac Muscle Contraction Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Regulation Of Ventricular Cardiac Muscle Cell Membrane Depolarization G Protein-coupled Receptor Signaling Pathway Renal Water Transport Regulation Of System Process Ammonium Channel Activity Regulation Of Atrial Cardiac Muscle Cell Membrane Depolarization Ammonium Transmembrane Transport Regulation Of Blood Circulation Calcium-mediated Signaling Metal Ion Transport Regulation Of Striated Muscle Contraction	Protein Localization To Plasma Membrane Protein Localization To Cell Periphery Negative Regulation Of Fatty Acid Transport Positive Regulation Of Translational Initiation Regulation Of Translational Initiation Protein Localization To Membrane Symbiont-mediated Disruption Of Host Cell PML Body Localization Within Membrane Negative Regulation Of Long-chain Fatty Acid Import Across Plasma Membrane Regulation Of Proteolysis Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Fatty Acid Transport Positive Regulation Of Protein Metabolic Process Golgi To Plasma Membrane Protein Transport Regulation Of Glucose Metabolic Process Cytoplasmic Pattern Recognition Receptor Signaling Pathway Negative Regulation Of Lipid Transport Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Proteolysis Cellular Localization Regulation Of Long-chain Fatty Acid Import Into Cell Peripheral Nervous System Myelin Maintenance Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Translational Initiation Regulation Of Signal Transduction By P53 Class Mediator Regulation Of Protein Localization Regulation Of Protein Catabolic Process Regulation Of Generation Of Precursor Metabolites And Energy Positive Regulation Of Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Lipid Metabolic Process Negative Regulation Of Proteolysis Negative Regulation Of PERK-mediated Unfolded Protein Response Regulation Of D-glucose Import Positive Regulation Of JUN Kinase Activity Regulation Of Lipid Catabolic Process Membrane Golgi To Plasma Membrane Transport Negative Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Localization To Cell Periphery Positive Regulation Of Translation Negative Regulation Of Transport TORC1 Signaling Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Protein Targeting To Vacuole Involved In Autophagy Toll-like Receptor 3 Signaling Pathway Myelin Maintenance Pattern Recognition Receptor Signaling Pathway Regulation Of PERK-mediated Unfolded Protein Response
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