ARLN and PLN

Number of citations of the paper that reports this interaction (PubMedID 39261533)
50

Data Source:
BioGRID (fluorescent resonance energy transfer)

		ARLN	PLN
Description		allregulin	phospholamban
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Sarcoplasmic Reticulum Mitochondrial Membrane Vesicle Protein-containing Complex Sarcoplasmic Reticulum Membrane Perinuclear Region Of Cytoplasm Calcium Ion-transporting ATPase Complex Phospholamban Complex
	Molecular Function	Protein Binding	Enzyme Inhibitor Activity Protein Binding ATPase Inhibitor Activity Identical Protein Binding Protein Homodimerization Activity Transmembrane Transporter Binding ATPase Binding Transporter Inhibitor Activity
	Biological Process		Acrosome Assembly Regulation Of The Force Of Heart Contraction Calcium Ion Transport Intracellular Calcium Ion Homeostasis Notch Signaling Pathway Spermatogenesis Blood Circulation Regulation Of Heart Contraction Visual Learning Response To Zinc Ion Negative Regulation Of Heart Rate Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Response To Insulin Response To Testosterone Locomotor Rhythm Negative Regulation Of Heart Contraction Muscle Cell Cellular Homeostasis Cardiac Muscle Tissue Development Circadian Sleep/wake Cycle, Sleep Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Calcium Ion Transport Negative Regulation Of Calcium Ion Transport Relaxation Of Cardiac Muscle Regulation Of Cardiac Muscle Cell Contraction Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Involved In Heart Process Regulation Of Cardiac Muscle Cell Membrane Potential Regulation Of The Force Of Heart Contraction By Cardiac Conduction Regulation Of Calcium Ion Import Negative Regulation Of Calcium Ion Import Regulation Of Relaxation Of Muscle Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Negative Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Regulation Of Relaxation Of Cardiac Muscle Negative Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum
Pathways			Ion homeostasis Ion transport by P-type ATPases
Drugs
Diseases
GWAS			Atrial fibrillation ( 28416818 30061737) Cardiac structure and function ( 19584346) Hypertrophic cardiomyopathy ( 33495597) Hypertrophic cardiomyopathy (sarcomere negative) ( 33495597) QRS complex (Sokolow-Lyon) ( 27659466) QRS duration ( 27577874 27659466) QT interval ( 19305408 19305409 19587794 23166209 24952745 29874175) Resting heart rate ( 27798624)
Interacting Genes		73 interacting genes: ADGRG3 AQP2 AQP6 ARL13B ATP2A2 BCL2L13 BIK C5AR2 CALM1 CCRL2 CD79A CISD2 CLDN9 CREB3L1 CXCR2 CYBC1 EBP ELN ELOVL4 ERGIC3 FAM174A FAM209A FFAR2 GJA5 GJB4 GJB5 GLP1R GPR61 GPX8 HHATL HTR2C JAGN1 LAPTM5 LMNA LY6G6C MILR1 MMD MMGT1 MRM3 MS4A3 NCAPH2 PLEKHO1 PLN PTGES REEP4 RETREG3 RHBDL1 RHCG SCN3B SERINC2 SHISAL1 SLC10A6 SLC14A2 SLC19A3 SLC35E3 SLC35H1 SLC39A2 SLC41A3 SLC71A2 SLCO3A1 SMO SSMEM1 STX1A SYNPR TIMMDC1 TM4SF19 TMEM101 TMEM237 TMEM248 TMEM45A TMEM45B TMEM51 YIF1A	68 interacting genes: AQP6 ARL13B ARLN ASGR2 ATP2A1 ATP2A2 ATP6V0E1 BCL2L13 BIK CD53 CLDN7 CLEC2D CPLX4 CREB3 CREB3L1 DMPK DVL3 EDA ELN ELOVL4 ERGIC3 FAM209A FKBP8 FNDC9 GJA8 GPR152 GPR37L1 GPX8 HIBADH HSD17B13 KIR2DL3 LDLRAD1 LSMEM2 MFF MGST2 MGST3 MS4A7 MTIF3 MUC1 PLPPR1 PPP1R3A PRKACA RTN3 S100A1 SAR1A SDC3 SIT1 SLC14A2 SLC30A8 SLC34A2 SLC35H1 SLC39A2 SLC61A1 SLN SPACA1 SPAG4 STX1A STX2 TMEM106C TMEM179B TMEM205 TMEM31 TMEM45A TMEM45B TMEM52B TMEM79 TMEM86B TMPRSS2
Entrez ID		401152	5350
HPRD ID		14223	01395
Ensembl ID		ENSG00000164096	ENSG00000198523
Uniprot IDs		Q8WVX3	P26678 Q5R352
PDB IDs			1PLP 1ZLL 2HYN 6Y40 7E0Z 7E11 7E12
Enriched GO Terms of Interacting Partners?		Membrane Transmembrane Transport Protein Binding Plasma Membrane Calcium Ion-transporting ATPase Complex Endoplasmic Reticulum Membrane G Protein-coupled Receptor Activity Connexin Complex Regulation Of Heart Rate Gap Junction Channel Activity Carbon Dioxide Transmembrane Transporter Activity One-carbon Compound Transport Carbon Dioxide Transmembrane Transport Gap Junction Regulation Of Heart Contraction Regulation Of Cardiac Muscle Cell Action Potential Transporter Inhibitor Activity SA Node Cell Action Potential Transmembrane Transporter Binding Mitochondrion-endoplasmic Reticulum Membrane Tethering Regulation Of Cardiac Muscle Cell Membrane Potential Autophagosome Membrane Docking Regulation Of Cardiac Muscle Contraction Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Regulation Of Ventricular Cardiac Muscle Cell Membrane Depolarization G Protein-coupled Receptor Signaling Pathway Renal Water Transport Regulation Of System Process Ammonium Channel Activity Regulation Of Atrial Cardiac Muscle Cell Membrane Depolarization Ammonium Transmembrane Transport Regulation Of Blood Circulation Calcium-mediated Signaling Metal Ion Transport Regulation Of Striated Muscle Contraction	Membrane Endoplasmic Reticulum Membrane Protein Binding Sarcoplasmic Reticulum Positive Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Sarcoplasmic Reticulum Membrane Endoplasmic Reticulum Sarcoplasmic Reticulum Calcium Ion Transport Calcium Ion Import Into Sarcoplasmic Reticulum Glutathione Peroxidase Activity Leukotriene-C4 Synthase Activity Regulation Of Cardiac Conduction Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?