LMX1B and LDB1

Number of citations of the paper that reports this interaction (PubMedID 12792813)
0

Data Source:
HPRD (two hybrid)

		LMX1B	LDB1
Description		LIM homeobox transcription factor 1 beta	LIM domain binding 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Cell Leading Edge Protein-containing Complex RNA Polymerase II Transcription Regulator Complex Beta-catenin-TCF Complex
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	DNA Binding Chromatin Binding Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Enzyme Binding LIM Domain Binding Identical Protein Binding Protein Homodimerization Activity RNA Polymerase II-specific DNA-binding Transcription Factor Binding DNA-binding Transcription Factor Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Dorsal/ventral Pattern Formation Neuron Differentiation Positive Regulation Of Transcription By RNA Polymerase II Dopaminergic Neuron Differentiation	Negative Regulation Of Transcription By RNA Polymerase II Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Gastrulation With Mouth Forming Second Hair Follicle Development Transcription By RNA Polymerase II Cell Adhesion Nervous System Development Anterior/posterior Axis Specification Epithelial Structure Maintenance Wnt Signaling Pathway Cerebellum Development Cerebellar Purkinje Cell Differentiation Cellular Component Assembly Neuron Differentiation Regulation Of Cell Migration Positive Regulation Of Transcription Elongation By RNA Polymerase II Somatic Stem Cell Population Maintenance Regulation Of Kinase Activity Negative Regulation Of Erythrocyte Differentiation Positive Regulation Of Cell Adhesion Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Hemoglobin Biosynthetic Process Regulation Of Focal Adhesion Assembly Head Development
Pathways			RUNX1 regulates transcription of genes involved in differentiation of HSCs Regulation of expression of SLITs and ROBOs Cardiogenesis Expression and translocation of olfactory receptors
Drugs
Diseases		Patella dysplasias, including: Small patella syndrome (SPS); Nail-patella syndrome; Ear-patella-short statute syndrome
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Adult body size ( 32376654) Appendicular lean mass ( 33097823) Body fat mass ( 28552196) Body mass index ( 28892062 20935630 28552196 26961502 25673413) Body size at age 10 ( 32376654) Breast cancer ( 31757997 29059683) C-reactive protein levels ( 31622379) Calcium levels ( 29403010) Childhood body mass index ( 33045005 26604143) Chin dimples ( 27182965) Eyebrow thickness ( 26926045) Glaucoma ( 31959993 30054594) Glaucoma (high intraocular pressure) ( 33627673) Glaucoma (multi-trait analysis) ( 31959993) Glaucoma (primary open-angle) ( 29891935 33627673 29449654) Heel bone mineral density ( 30598549) Intraocular pressure ( 30054594 29785010 29617998 31959993) Medication use (antiglaucoma preparations and miotics) ( 31015401) Mental health related quality of life ( 33578652) Monobrow ( 27182965) Multiple system atrophy ( 27629089) Open-angle glaucoma and optic cup area ( 29449654) Osteoarthritis (hip) ( 30374069) Social communication problems ( 24564958) Trunk fat mass ( 28552196)	General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Mean reticulocyte volume ( 32888494) Pulse pressure ( 30578418)
Interacting Genes		7 interacting genes: APP CFTR CREB5 HOXA1 LDB1 NPHS2 TCF3	27 interacting genes: ATXN1 CTDSP1 DNMT3L DSCAM ESR1 IRAK3 ISL1 LCOR LHX1 LHX3 LMO1 LMO2 LMO3 LMO4 LMX1A LMX1B LSM7 POLR1B PSMA1 PSMD10 RLIM SP1 SSBP1 SSBP2 SSBP3 SSBP4 TOLLIP
Entrez ID		4010	8861
HPRD ID		03986	09144
Ensembl ID		ENSG00000136944	ENSG00000198728
Uniprot IDs		B7ZLH2 O60663 Q6ISE0	A0A6E1WJ75 Q86U70
PDB IDs			2XJY 2XJZ 2YPA 6TYD 7OB5 7OB8 8HIB 8SSU 9F5B
Enriched GO Terms of Interacting Partners?		Protein-containing Complex Amyloid-beta Complex Growth Cone Lamellipodium Positive Regulation Of RNA Biosynthetic Process DNA Binding System Development Visual Behavior Enzyme Binding Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of RNA Metabolic Process Positive Regulation Of Toll Signaling Pathway Cellular Response To CAMP Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of DNA-templated Transcription Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Semicircular Canal Formation Chromatin Renal System Development Acetylcholine Receptor Activator Activity Protein-folding Chaperone Binding PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Transcription By RNA Polymerase II Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Positive Regulation Of Neuron Differentiation Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To CAMP Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Anion Channel Activity Positive Regulation Of Monoatomic Anion Transport Abducens Nerve Formation Optokinetic Behavior Vitamin D Response Element Binding RNA Polymerase II Transcription Regulator Complex Metanephric Podocyte Development Recycling Endosome Response To Purine-containing Compound Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway	Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Metabolic Process Nucleus Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Biosynthetic Process Neuron Projection Guidance Axon Guidance Transcription Regulator Complex Spinal Cord Motor Neuron Cell Fate Specification DNA Binding Cell Differentiation In Spinal Cord Transcription Coregulator Binding Spinal Cord Association Neuron Differentiation Neuron Differentiation Positive Regulation Of Anterior Head Development Central Nervous System Neuron Differentiation Motor Neuron Axon Guidance Neuron Projection Development BHLH Transcription Factor Binding Neuron Fate Specification RNA Polymerase II-specific DNA-binding Transcription Factor Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Single-stranded DNA Binding Nuclear Estrogen Receptor Binding Metal Ion Binding Mesendoderm Development Negative Regulation Of RNA Metabolic Process Regionalization Sequence-specific DNA Binding Negative Regulation Of Macromolecule Metabolic Process Vagina Development Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?