LMX1B

Gene Name		LIM homeobox transcription factor 1, beta
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding
	Biological Process	In Utero Embryonic Development Neuron Migration Trabecular Meshwork Development Transcription, DNA-templated Regulation Of Transcription, DNA-templated Multicellular Organismal Development Cell Proliferation Dorsal/ventral Pattern Formation Cerebellum Morphogenesis Central Nervous System Neuron Development Neuron Differentiation Collagen Fibril Organization Midbrain Development Limb Morphogenesis Organ Growth Positive Regulation Of Transcription From RNA Polymerase II Promoter Dopaminergic Neuron Differentiation
Pathways
Drugs
Diseases
GWAS		Body mass index ( 20935630)
Protein-protein Interactions		4 interactors: APP LDB1 SSBP3 TCF3
Entrez ID		4010
HPRD ID		03986
Ensembl ID		ENSG00000136944
Uniprot IDs		B7ZLH2 O60663 Q6ISE0
PDB IDs
Enriched GO Terms of Interacting Partners?		Brain Development Head Development Central Nervous System Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Anterior/posterior Pattern Specification Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Histone H3 Acetylation Positive Regulation Of Cellular Biosynthetic Process Pattern Specification Process Regulation Of Transcription From RNA Polymerase II Promoter Somatic Stem Cell Maintenance Anterior/posterior Axis Specification Nervous System Development Anatomical Structure Morphogenesis Negative Regulation Of Cell Differentiation Histone Acetylation Axis Specification Internal Peptidyl-lysine Acetylation Positive Regulation Of Cellular Metabolic Process Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Histone H3-K4 Acetylation Midbrain-hindbrain Boundary Initiation Prechordal Plate Formation Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Protein Acetylation Stem Cell Maintenance Organ Development Positive Regulation Of Hemoglobin Biosynthetic Process Synaptic Growth At Neuromuscular Junction Positive Regulation Of Anterior Head Development RNA Metabolic Process Embryo Development Cell Differentiation Positive Regulation Of Metabolic Process Gene Expression Collateral Sprouting In Absence Of Injury Positive Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Regulation Of Mitotic Cell Cycle Phase Transition Skin Development Regulation Of Cell Cycle Phase Transition Neural Plate Anterior/posterior Regionalization Stem Cell Development Peptidyl-lysine Modification Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Hemoglobin Biosynthetic Process Wnt Signaling Pathway
Tagcloud ?		aer alternatives assure axes brief brought clues complements congenital correct deciphering deformity digit ectoderm en1 eventually fgfs limb limbs malformation manners modules organized p63 quantity shh sterile wnt7a zpa