LMO2 and FAM154A

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		LMO2	FAM154A
Gene Name		LIM domain only 2 (rhombotin-like 1)	family with sequence similarity 154, member A
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Transcription Factor Complex
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity RNA Polymerase II Activating Transcription Factor Binding RNA Polymerase II Transcription Factor Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Chromatin Binding Protein Binding Zinc Ion Binding BHLH Transcription Factor Binding Cofactor Binding E-box Binding	Protein Binding
	Biological Process	Multicellular Organismal Development Embryonic Hemopoiesis MRNA Transcription From RNA Polymerase II Promoter Negative Regulation Of Erythrocyte Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Thyroid Hormone Stimulus
Pathways
Drugs
Diseases
GWAS		Cognitive performance ( 19734545)	Non-small cell lung cancer ( 23144319)
Protein-Protein Interactions		96 interactors: ABI2 ADAMTSL4 AES AGTRAP AIMP2 ALDH6A1 AXIN1 BANP BEX2 BLZF1 C1orf94 CALCOCO2 CCDC33 CCDC36 CDC25A CDC5L CDX4 CLHC1 CMTM5 CORO1A CORO1C DAZAP2 DBF4B DDIT3 DRAP1 EHMT2 ELF2 ERBB2IP FAM154A FHL3 GATA1 GATA2 GATA3 GFAP GOLGA2 GRB2 HNRNPC HNRNPM HOOK1 IFT43 IKZF3 ISL1 KANK2 KDM5A KIF3B KRT15 KRT40 KRTAP10-7 LDB1 LYL1 LZTS2 MAGEA8 MAPRE1 MAPRE2 MAPRE3 MBIP MLLT4 MRFAP1L1 MTUS2 N4BP2L2 NCAPH2 NHLH1 NIF3L1 NOTCH2NL NUP62 NUTM1 PDE9A PHC2 PRKG1 RBBP8 REL RELA RINT1 RLIM ROCK1 SKP1 SMAD2 SOX5 SP1 SPERT SSX2IP STAT1 STAT3 STIP1 TAL1 TAL2 TFPT TLX3 TRIM23 TRIM54 TRIP6 TSC22D4 TUFT1 UBE2I ZFP64 ZNF24	18 interactors: ACTN2 CRK FAM124A FHL2 FHL3 GLYCTK HOXA1 KIR3DX1 LMO1 LMO2 MVP OSGIN1 POLR1C SORBS3 STK16 TRIP6 VPS28 ZMYND19
Entrez ID		4005	158297
HPRD ID		01586	16676
Ensembl ID		ENSG00000135363	ENSG00000155875
Uniprot IDs		P25791	F6S232 Q8IYX7
PDB IDs		2XJY 2XJZ 2YPA
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process RNA Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Developmental Process Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Heterocycle Metabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Cellular Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Nitrogen Compound Metabolic Process Cell Cycle Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Organelle Organization Biosynthetic Process Multicellular Organismal Development Positive Regulation Of Metabolic Process Anatomical Structure Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Differentiation Negative Regulation Of Signal Transduction Cell Fate Commitment Definitive Hemopoiesis Regulation Of Cell Differentiation Negative Regulation Of Cell Differentiation Mitotic Cell Cycle Regulation Of Cell Proliferation Negative Regulation Of Signaling	Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Focal Adhesion Assembly Cell-substrate Adhesion Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Adherens Junction Assembly Regulation Of RNA Metabolic Process Cell-substrate Junction Assembly Positive Regulation Of Cellular Metabolic Process Optokinetic Behavior Abducens Nerve Formation Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Facial Nucleus Development Adherens Junction Organization Positive Regulation Of Macromolecule Biosynthetic Process Transcription, DNA-templated Positive Regulation Of Gene Expression Rhombomere 4 Development Atrial Cardiac Muscle Cell Development Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Semicircular Canal Formation Regulation Of Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Rhombomere 3 Development Rhombomere 5 Development Positive Regulation Of Metabolic Process Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Release Of Cytoplasmic Sequestered NF-kappaB Endosome Transport Via Multivesicular Body Sorting Pathway Microspike Assembly Late Endosome To Vacuole Transport Cell-matrix Adhesion Negative Regulation Of Protein Localization To Cell Surface Embryonic Neurocranium Morphogenesis Platelet Activation Negative Regulation Of Erythrocyte Differentiation Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Outer Ear Morphogenesis Actin Filament-based Process Cell Junction Assembly Semicircular Canal Morphogenesis Rhombomere Development Cellular Response To Thyroid Hormone Stimulus Viral Protein Processing Negative Regulation Of Cellular Metabolic Process
Tagcloud ?		chimeric chromosomal contribution die disruption embryonic encodes erythropoiesis finger hematopoiesis hematopoietic homozygous leukemias lim lineage lineages master null precluded prevents probably reintroduction rescues sac stages tal1 translocations vector yolk
Tagcloud (Difference) ?		chimeric chromosomal contribution die disruption embryonic encodes erythropoiesis finger hematopoiesis hematopoietic homozygous leukemias lim lineage lineages master null precluded prevents probably reintroduction rescues sac stages tal1 translocations vector yolk
Tagcloud (Intersection) ?