LMO2 and MAGEA8

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		LMO2	MAGEA8
Gene Name		LIM domain only 2 (rhombotin-like 1)	melanoma antigen family A, 8
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Transcription Factor Complex	Cellular_component
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity RNA Polymerase II Activating Transcription Factor Binding RNA Polymerase II Transcription Factor Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Chromatin Binding Protein Binding Zinc Ion Binding BHLH Transcription Factor Binding Cofactor Binding E-box Binding	Molecular_function
	Biological Process	Multicellular Organismal Development Embryonic Hemopoiesis MRNA Transcription From RNA Polymerase II Promoter Negative Regulation Of Erythrocyte Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Thyroid Hormone Stimulus	Biological_process
Pathways
Drugs
Diseases
GWAS		Cognitive performance ( 19734545)
Protein-Protein Interactions		96 interactors: ABI2 ADAMTSL4 AES AGTRAP AIMP2 ALDH6A1 AXIN1 BANP BEX2 BLZF1 C1orf94 CALCOCO2 CCDC33 CCDC36 CDC25A CDC5L CDX4 CLHC1 CMTM5 CORO1A CORO1C DAZAP2 DBF4B DDIT3 DRAP1 EHMT2 ELF2 ERBB2IP FAM154A FHL3 GATA1 GATA2 GATA3 GFAP GOLGA2 GRB2 HNRNPC HNRNPM HOOK1 IFT43 IKZF3 ISL1 KANK2 KDM5A KIF3B KRT15 KRT40 KRTAP10-7 LDB1 LYL1 LZTS2 MAGEA8 MAPRE1 MAPRE2 MAPRE3 MBIP MLLT4 MRFAP1L1 MTUS2 N4BP2L2 NCAPH2 NHLH1 NIF3L1 NOTCH2NL NUP62 NUTM1 PDE9A PHC2 PRKG1 RBBP8 REL RELA RINT1 RLIM ROCK1 SKP1 SMAD2 SOX5 SP1 SPERT SSX2IP STAT1 STAT3 STIP1 TAL1 TAL2 TFPT TLX3 TRIM23 TRIM54 TRIP6 TSC22D4 TUFT1 UBE2I ZFP64 ZNF24	8 interactors: BEX5 GCA LMO2 LXN MAGEB4 MTUS2 PKD2 UBE3A
Entrez ID		4005	4107
HPRD ID		01586	02278
Ensembl ID		ENSG00000135363	ENSG00000156009
Uniprot IDs		P25791	B2R9W4 P43361
PDB IDs		2XJY 2XJZ 2YPA
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process RNA Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Developmental Process Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Heterocycle Metabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Cellular Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Nitrogen Compound Metabolic Process Cell Cycle Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Organelle Organization Biosynthetic Process Multicellular Organismal Development Positive Regulation Of Metabolic Process Anatomical Structure Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Differentiation Negative Regulation Of Signal Transduction Cell Fate Commitment Definitive Hemopoiesis Regulation Of Cell Differentiation Negative Regulation Of Cell Differentiation Mitotic Cell Cycle Regulation Of Cell Proliferation Negative Regulation Of Signaling	Sperm Entry Metanephric Cortex Development Metanephric Cortical Collecting Duct Development Detection Of Nodal Flow Protein Kinase D Signaling Metanephric Smooth Muscle Tissue Development Renal Artery Morphogenesis Detection Of Abiotic Stimulus Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Histone Deacetylase Activity Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Hydrostatic Pressure Positive Regulation Of Endothelial Cell Chemotaxis By VEGF-activated Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Cell Migration By Vascular Endothelial Growth Factor Signaling Pathway Metanephric Ascending Thin Limb Development Regulation Of Histone Deacetylase Activity Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Deacetylase Activity Metanephric Part Of Ureteric Bud Development Determination Of Liver Left/right Asymmetry Metanephric S-shaped Body Morphogenesis Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle Metanephric Loop Of Henle Development Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Endothelial Cell Chemotaxis Mesonephric Duct Development S-shaped Body Morphogenesis Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Metanephric Distal Tubule Development Negative Regulation Of Erythrocyte Differentiation Response To Hydrostatic Pressure Endothelial Tube Morphogenesis Cellular Response To Thyroid Hormone Stimulus Positive Regulation Of Macromolecule Biosynthetic Process Metanephric Collecting Duct Development Positive Regulation Of Gene Expression Urogenital System Development MRNA Transcription From RNA Polymerase II Promoter Positive Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Loop Of Henle Development Positive Regulation Of Cellular Biosynthetic Process Distal Tubule Development MRNA Transcription Collecting Duct Development Cellular Response To Fluid Shear Stress Response To Thyroid Hormone Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of T Cell Receptor Signaling Pathway
Tagcloud ?		chimeric chromosomal contribution die disruption embryonic encodes erythropoiesis finger hematopoiesis hematopoietic homozygous leukemias lim lineage lineages master null precluded prevents probably reintroduction rescues sac stages tal1 translocations vector yolk
Tagcloud (Difference) ?		chimeric chromosomal contribution die disruption embryonic encodes erythropoiesis finger hematopoiesis hematopoietic homozygous leukemias lim lineage lineages master null precluded prevents probably reintroduction rescues sac stages tal1 translocations vector yolk
Tagcloud (Intersection) ?