LMO2 and MAPRE2

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		LMO2	MAPRE2
Gene Name		LIM domain only 2 (rhombotin-like 1)	microtubule-associated protein, RP/EB family, member 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Transcription Factor Complex	Cytoplasm Microtubule Cytoskeleton Microtubule Plus-end
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity RNA Polymerase II Activating Transcription Factor Binding RNA Polymerase II Transcription Factor Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Chromatin Binding Protein Binding Zinc Ion Binding BHLH Transcription Factor Binding Cofactor Binding E-box Binding	Microtubule Binding
	Biological Process	Multicellular Organismal Development Embryonic Hemopoiesis MRNA Transcription From RNA Polymerase II Promoter Negative Regulation Of Erythrocyte Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Thyroid Hormone Stimulus	Mitotic Nuclear Division Signal Transduction Cell Proliferation Cell Division
Pathways
Drugs
Diseases
GWAS		Cognitive performance ( 19734545)
Protein-Protein Interactions		96 interactors: ABI2 ADAMTSL4 AES AGTRAP AIMP2 ALDH6A1 AXIN1 BANP BEX2 BLZF1 C1orf94 CALCOCO2 CCDC33 CCDC36 CDC25A CDC5L CDX4 CLHC1 CMTM5 CORO1A CORO1C DAZAP2 DBF4B DDIT3 DRAP1 EHMT2 ELF2 ERBB2IP FAM154A FHL3 GATA1 GATA2 GATA3 GFAP GOLGA2 GRB2 HNRNPC HNRNPM HOOK1 IFT43 IKZF3 ISL1 KANK2 KDM5A KIF3B KRT15 KRT40 KRTAP10-7 LDB1 LYL1 LZTS2 MAGEA8 MAPRE1 MAPRE2 MAPRE3 MBIP MLLT4 MRFAP1L1 MTUS2 N4BP2L2 NCAPH2 NHLH1 NIF3L1 NOTCH2NL NUP62 NUTM1 PDE9A PHC2 PRKG1 RBBP8 REL RELA RINT1 RLIM ROCK1 SKP1 SMAD2 SOX5 SP1 SPERT SSX2IP STAT1 STAT3 STIP1 TAL1 TAL2 TFPT TLX3 TRIM23 TRIM54 TRIP6 TSC22D4 TUFT1 UBE2I ZFP64 ZNF24	17 interactors: APC APP AURKA AURKB CDK2 CDK4 CLASP2 CLIP1 CRTAC1 LMO2 MAPRE1 MAPRE3 NIF3L1 PAXIP1 TRAF1 TRAIP TXN2
Entrez ID		4005	10982
HPRD ID		01586	16157
Ensembl ID		ENSG00000135363	ENSG00000166974
Uniprot IDs		P25791	G5E9I6 Q15555
PDB IDs		2XJY 2XJZ 2YPA
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process RNA Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Developmental Process Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Heterocycle Metabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Cellular Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Nitrogen Compound Metabolic Process Cell Cycle Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Organelle Organization Biosynthetic Process Multicellular Organismal Development Positive Regulation Of Metabolic Process Anatomical Structure Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Differentiation Negative Regulation Of Signal Transduction Cell Fate Commitment Definitive Hemopoiesis Regulation Of Cell Differentiation Negative Regulation Of Cell Differentiation Mitotic Cell Cycle Regulation Of Cell Proliferation Negative Regulation Of Signaling	Regulation Of Microtubule Polymerization Or Depolymerization Mitotic Nuclear Division Negative Regulation Of Microtubule Polymerization Or Depolymerization Cell Division Mitotic Cell Cycle Process Regulation Of Microtubule Cytoskeleton Organization Mitotic Cell Cycle Regulation Of Protein Binding Regulation Of Microtubule-based Process Negative Regulation Of Microtubule Depolymerization Cell Cycle Process Regulation Of Binding Positive Regulation Of Cell Cycle Negative Regulation Of Cytoskeleton Organization Cell Cycle Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Cell Cycle Process Microtubule Cytoskeleton Organization Negative Regulation Of Protein Complex Disassembly Positive Regulation Of Microtubule Plus-end Binding Microtubule-based Process Regulation Of Cell Cycle Process Regulation Of Protein Depolymerization Mitotic Cell Cycle Phase Transition Regulation Of Cytoskeleton Organization Cell Cycle Phase Transition Regulation Of Microtubule Polymerization Regulation Of Protein Complex Disassembly Regulation Of Organelle Organization Regulation Of Cell Cycle Histone Phosphorylation Spindle Stabilization Regulation Of Mitotic Cell Cycle Negative Regulation Of Protein Binding Negative Regulation Of Cell Cycle Organelle Organization Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Positive Regulation Of Microtubule Polymerization Histone-serine Phosphorylation Positive Regulation Of Macromolecule Biosynthetic Process Chromosome Organization Negative Regulation Of Binding Positive Regulation Of Gene Expression Microtubule Organizing Center Organization Positive Regulation Of Cellular Biosynthetic Process Protein Localization To Cytoskeleton Regulation Of Protein Complex Assembly
Tagcloud ?		chimeric chromosomal contribution die disruption embryonic encodes erythropoiesis finger hematopoiesis hematopoietic homozygous leukemias lim lineage lineages master null precluded prevents probably reintroduction rescues sac stages tal1 translocations vector yolk	100nm 48h 81m anapc13 calm2 carcinogenic diarrheic drawing exhaustive explanation hn1 malat1 mllt11 molluscs oa okadaic pathologies poisoning positives pttg1 rodents sga shellfish shsy5y ssh subtractive tax1bp1 toxins tumourigenesis
Tagcloud (Difference) ?		chimeric chromosomal contribution die disruption embryonic encodes erythropoiesis finger hematopoiesis hematopoietic homozygous leukemias lim lineage lineages master null precluded prevents probably reintroduction rescues sac stages tal1 translocations vector yolk	100nm 48h 81m anapc13 calm2 carcinogenic diarrheic drawing exhaustive explanation hn1 malat1 mllt11 molluscs oa okadaic pathologies poisoning positives pttg1 rodents sga shellfish shsy5y ssh subtractive tax1bp1 toxins tumourigenesis
Tagcloud (Intersection) ?