STMN1 and HUNK

Number of citations of the paper that reports this interaction (PubMedID 35914814)
83

Data Source:
BioGRID (two hybrid)

		STMN1	HUNK
Description		stathmin 1	hormonally up-regulated Neu-associated kinase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Microtubule Membrane Neuron Projection Extracellular Exosome	Cytoplasm
	Molecular Function	Protein Binding Tubulin Binding	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity
	Biological Process	Mitotic Cytokinesis Microtubule Depolymerization Mitotic Spindle Organization Signal Transduction Nervous System Development Axonogenesis Response To Virus Cell Differentiation Regulation Of Cell Migration Regulation Of Microtubule Polymerization Or Depolymerization Negative Regulation Of Microtubule Polymerization Neuron Projection Development Negative Regulation Of Rho Protein Signal Transduction Intracellular Signal Transduction Hepatocyte Growth Factor Receptor Signaling Pathway Negative Regulation Of Stress Fiber Assembly Establishment Of Skin Barrier Negative Regulation Of Thrombin-activated Receptor Signaling Pathway Negative Regulation Of Guanyl-nucleotide Exchange Factor Activity	Signal Transduction Intracellular Signal Transduction
Pathways		Nuclear signaling by ERBB4
Drugs
Diseases
GWAS			Crohn's disease ( 32581322) Joint damage progression in ACPA-negative rheumatoid arthritis ( 26077402) LDL cholesterol levels in HIV infection ( 33109212) Response to antipsychotic treatment in schizophrenia (reasoning) ( 21107309) Type 2 diabetes ( 21490949) Vitiligo ( 19890347)
Interacting Genes		21 interacting genes: CAMK2G CDK1 CDKN1B CEBPA CHEK2 CSNK2A1 ERBB2 FANCC GLP1R HSPA5 HSPA8 HUNK LINC00632 MAPK3 PRKACA PRKCA SEPTIN2 SESTD1 STAT3 UBQLN4 UHMK1	92 interacting genes: AARS1 ABLIM1 ACTR8 AGAP3 AIP AKAP8L AKR1C3 ALAD ANXA7 APBA2 APPL2 ARMCX4 ASCL1 ASPA ATP5F1B BIN1 CAMK1 CCAR1 CLU COG2 COPA COPS4 COPS5 CTDSP1 CTR9 CXXC5 DIS3L DLAT DLST DNAJA1 DST EEF1A2 EFNA1 EIF4G1 EPRS1 GEN1 HEATR6 HEY1 IFT81 IFT88 KDM6A KIF3A LIMK1 LNX1 LRSAM1 LURAP1 MAGED1 MBD1 MCHR1 MGAT5B MOAP1 MORF4L2 MTMR10 MYCBP2 N4BP2L2 NAPA NEUROD2 OLR1 PICK1 PITHD1 PPP1R16B PTPRA PTPRD RAB5B RABEP1 SH2B1 SLC6A1 SMARCE1 SMYD2 SNRNP48 SNRNP70 SORBS1 SPARCL1 STMN1 STUB1 TAF1 TOMM6 TRIM68 TTC28 UBE2O USP8 VCPIP1 VPS35L VSNL1 ZBTB44 ZNF197 ZNF292 ZNF343 ZNF655 ZNF662 ZNF76 ZNF793
Entrez ID		3925	30811
HPRD ID		01047	09410
Ensembl ID		ENSG00000117632	ENSG00000142149
Uniprot IDs		A0A140VJW2 P16949	P57058
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Serine Kinase Activity Protein Kinase Activity Protein Serine/threonine Kinase Activity Kinase Activity Phosphorylation Nucleotide Binding ATP Binding Nucleoplasm Protein Phosphorylation Regulation Of Protein Catabolic Process Intracellular Signal Transduction Response To Stress Regulation Of Protein Metabolic Process Cellular Response To Stress Signal Transduction In Response To DNA Damage Regulation Of Cellular Component Organization Phosphate-containing Compound Metabolic Process Regulation Of Cell Cycle Regulation Of Macroautophagy Regulation Of Proteasomal Protein Catabolic Process Regulation Of Autophagy Intracellular Signaling Cassette Regulation Of Transport Regulation Of Protein Localization Transferase Activity Signal Transduction Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Response To Nutrient Levels Intracellular Protein Localization Ubiquitin Protein Ligase Binding Regulation Of Cellular Localization DNA Damage Response Regulation Of Establishment Of Protein Localization Regulation Of Cellular Response To Stress Post-translational Protein Targeting To Membrane, Translocation Intracellular Protein Transport Positive Regulation Of Catabolic Process ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Cell Cycle Nucleic Acid Metabolic Process Mitotic Nuclear Membrane Disassembly Cellular Response To Glucagon Stimulus Positive Regulation Of Cell Population Proliferation Regulation Of Proteolysis Response To Hormone Protein Catabolic Process Negative Regulation Of Catabolic Process Interleukin-2-mediated Signaling Pathway	Nucleus Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Metal Ion Binding Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of Gene Expression Regulation Of Protein Catabolic Process Regulation Of Cellular Component Organization Negative Regulation Of Protein Metabolic Process Regulation Of DNA-templated Transcription Positive Regulation Of Cellular Component Organization Positive Regulation Of Amyloid Fibril Formation Protein Modification By Small Protein Conjugation Regulation Of RNA Biosynthetic Process DeNEDDylase Activity
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