LAMC1 and CCDC53

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		LAMC1	CCDC53
Gene Name		laminin, gamma 1 (formerly LAMB2)	coiled-coil domain containing 53
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Basement Membrane Laminin-1 Complex Extracellular Space Extracellular Matrix Laminin-10 Complex Laminin-11 Complex Extracellular Vesicular Exosome	Actin Cytoskeleton Intracellular Membrane-bounded Organelle WASH Complex
	Molecular Function	Extracellular Matrix Structural Constituent Glycosphingolipid Binding	Protein Binding
	Biological Process	Protein Complex Assembly Cell Adhesion Axon Guidance Endoderm Development Cell Migration Extracellular Matrix Disassembly Extracellular Matrix Organization Hemidesmosome Assembly Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Epithelial Cell Proliferation	Biological_process
Pathways		Axon guidance Laminin interactions ECM proteoglycans L1CAM interactions Non-integrin membrane-ECM interactions Degradation of the extracellular matrix
Drugs
Diseases
GWAS		Colorectal cancer ( 23266556)
Protein-Protein Interactions		13 interactors: ANTXR2 APP ATF7IP CCDC53 CENPU EIF3I LAMA5 NID1 NID2 SNAPIN SNX2 SRPK1 TANK	28 interactors: ABI2 BLOC1S6 CCHCR1 CEP55 CKAP4 DTNBP1 GDF9 GOLGA2 HAUS1 HSBP1 IFT20 KDM1A KRT6A LAMC1 LUC7L2 MCRS1 MOB1B NDC80 NUP62 OPTN PBXIP1 PCM1 PTN SDCBP SNAP25 SYCE1 TXLNA TXLNB
Entrez ID		3915	51019
HPRD ID		01030	13031
Ensembl ID		ENSG00000135862	ENSG00000120860
Uniprot IDs		P11047 Q6NVY8	F5GZ97 Q9Y3C0
PDB IDs
Enriched GO Terms of Interacting Partners?		Extracellular Matrix Organization Extracellular Structure Organization Basement Membrane Organization Cell-matrix Adhesion Viral Process Cell-substrate Adhesion Axon Cargo Transport Positive Regulation Of Late Endosome To Lysosome Transport Synaptic Growth At Neuromuscular Junction Extracellular Matrix Disassembly Collateral Sprouting In Absence Of Injury Terminal Button Organization Autophagic Vacuole Maturation Cell Recognition Cellular Component Assembly Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Lamellipodium Morphogenesis Collateral Sprouting Axon Midline Choice Point Recognition Cell Projection Organization Nephron Development Regulation Of Protein Binding Cell Adhesion Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Synapse Organization Organelle Organization Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly DNA Packaging Endocytosis Negative Regulation Of Neuron Differentiation	Organelle Organization Cell Differentiation Establishment Of Localization In Cell Organelle Localization Mitotic Cell Cycle Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Cellular Localization Developmental Process Synaptic Vesicle Docking Cell Cycle Mitotic Cell Cycle Process Cell Development Nervous System Development Cell Cycle Process Protein Localization Post-Golgi Vesicle-mediated Transport Microtubule-based Process Intracellular Transport Generation Of Neurons Cell Projection Organization Anterograde Synaptic Vesicle Transport Synaptic Vesicle Transport Membrane Organization Neurogenesis Melanosome Organization Pigment Granule Organization Microtubule-based Movement Anterograde Axon Cargo Transport Establishment Of Organelle Localization Neuron Development Cellular Process Multicellular Organismal Development Cellular Component Assembly Intraciliary Transport Establishment Of Protein Localization Anatomical Structure Development Movement Of Cell Or Subcellular Component Protein Localization To Golgi Apparatus Cytoskeleton Organization Neuron Differentiation Cell Division Regulation Of Primitive Erythrocyte Differentiation Opsin Transport Establishment Of Vesicle Localization Axon Cargo Transport Vesicle Organization Vesicle Localization Neuron Projection Development Positive Regulation Of Cell Proliferation
Tagcloud ?		5p adam10 brand clustered documented emerged erbb4 existed hdac7 helps igf1r intriguingly invasion meanwhile micrornas migration mir mirna mirnas overexpressed pax6 psen1 repressed simultaneously targets though tongue tscc utr
Tagcloud (Difference) ?		5p adam10 brand clustered documented emerged erbb4 existed hdac7 helps igf1r intriguingly invasion meanwhile micrornas migration mir mirna mirnas overexpressed pax6 psen1 repressed simultaneously targets though tongue tscc utr
Tagcloud (Intersection) ?