RHOG and MCF2

Number of citations of the paper that reports this interaction (PubMedID 12376551)
0

Data Source:
HPRD (in vitro)

		RHOG	MCF2
Description		ras homolog family member G	MCF.2 cell line derived transforming sequence
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Membrane Secretory Granule Membrane Cytoplasmic Vesicle Cell Projection Extracellular Exosome Postsynapse Glutamatergic Synapse	Cytoplasm Cytosol Cytoskeleton Membrane
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Protein Kinase Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Small GTPase-mediated Signal Transduction Rho Protein Signal Transduction Positive Regulation Of Cell Population Proliferation Regulation Of Cell Shape Rac Protein Signal Transduction Actin Cytoskeleton Organization Cortical Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Positive Regulation Of DNA-templated Transcription Cell Chemotaxis Activation Of GTPase Activity Regulation Of Postsynapse Assembly Regulation Of Ruffle Assembly Positive Regulation Of Protein Localization To Plasma Membrane	Dendrite Development Intracellular Signal Transduction Negative Regulation Of Axonogenesis Regulation Of Small GTPase Mediated Signal Transduction Cellular Response To Leukemia Inhibitory Factor
Pathways		GPVI-mediated activation cascade PIP3 activates AKT signaling Constitutive Signaling by Aberrant PI3K in Cancer RHO GTPases activate KTN1 Neutrophil degranulation PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling RHOG GTPase cycle	Axonal growth inhibition (RHOA activation) NRAGE signals death through JNK G alpha (12/13) signalling events RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOG GTPase cycle RAC3 GTPase cycle
Drugs
Diseases
GWAS		Eosinophilic esophagitis ( 34506852) Lymphocyte percentage of white cells ( 32888494) Malaria ( 31844061) Plateletcrit ( 32888494)	Metabolite levels ( 23823483)
Interacting Genes		24 interacting genes: ARHGDIA ARHGDIG CCR2 CEBPA DOCK1 ECT2 ELMO1 ELMO2 ELMOD2 ERCC6 IQGAP2 KTN1 MAP3K11 MCF2 MCF2L PLD1 RSPH1 SMAD1 SMAD4 TGFBR1 UBC VAV1 VAV2 VAV3	8 interacting genes: ERCC3 GNA13 GNB1 RAC1 RHOA RHOG STUB1 TNK2
Entrez ID		391	4168
HPRD ID		01537	02406
Ensembl ID		ENSG00000177105	ENSG00000101977
Uniprot IDs		P84095 Q6ICQ8	B2R9S6 P10911
PDB IDs		6UKA 7Y4A 8XM7 8ZJ2
Enriched GO Terms of Interacting Partners?		Intracellular Signal Transduction Intracellular Signaling Cassette Guanyl-nucleotide Exchange Factor Activity Small GTPase-mediated Signal Transduction Signal Transduction GTPase Activator Activity Regulation Of Small GTPase Mediated Signal Transduction Phagocytosis I-SMAD Binding Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-epsilon Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Rho GDP-dissociation Inhibitor Activity Cell Motility Fc-gamma Receptor Signaling Pathway Cell Migration Guanyl-nucleotide Exchange Factor Complex SMAD Protein Complex Heteromeric SMAD Protein Complex Fc Receptor Signaling Pathway Cytosol Positive Regulation Of Extracellular Matrix Assembly Endothelial Cell Activation Chemotaxis Cellular Response To Xenobiotic Stimulus Positive Regulation Of Intracellular Signal Transduction Locomotion Platelet Activation Cytoplasm Cell Surface Receptor Signaling Pathway Regulation Of Intracellular Signal Transduction Positive Regulation Of Signal Transduction Cell Chemotaxis Regulation Of Cell Size Regulation Of Synaptic Vesicle Cycle Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Interleukin-6-mediated Signaling Pathway Cardiac Conduction System Development MAPK Cascade Endocytosis Integrin-mediated Signaling Pathway Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of Extracellular Matrix Assembly SH3 Domain Binding SMAD Protein Signal Transduction Small GTPase Binding Positive Regulation Of Extracellular Matrix Organization Response To Xenobiotic Stimulus	Small GTPase-mediated Signal Transduction Intracellular Signaling Cassette GTPase Activity Regulation Of Postsynapse Assembly Intracellular Signal Transduction Postsynapse Rho Protein Signal Transduction G Protein Activity Regulation Of Cell Junction Assembly Regulation Of Synapse Organization Regulation Of Vascular Associated Smooth Muscle Contraction Secretory Granule Membrane GTP Binding Positive Regulation Of Protein Modification Process Focal Adhesion Regulation Of Cell Shape Regulation Of Postsynapse Organization Establishment Or Maintenance Of Cell Polarity Nucleotide Binding Regulation Of Synapse Assembly Rac Protein Signal Transduction Cerebral Cortex Cell Migration Regulation Of Ruffle Assembly Wnt Signaling Pathway, Planar Cell Polarity Pathway Positive Regulation Of Protein-containing Complex Assembly Heterotrimeric G-protein Complex Telencephalon Cell Migration Positive Regulation Of Protein Phosphorylation Positive Regulation Of Phosphorylation Regulation Of Protein Modification Process Semaphorin-plexin Signaling Pathway Substrate Adhesion-dependent Cell Spreading Forebrain Cell Migration Membrane Invagination Cortical Cytoskeleton Organization Regulation Of Cell Morphogenesis Regulation Of Fibroblast Migration Actin Filament Organization Non-canonical Wnt Signaling Pathway Positive Regulation Of Stress Fiber Assembly Brush Border Membrane Ficolin-1-rich Granule Membrane Regulation Of Cellular Component Organization Positive Regulation Of Phosphate Metabolic Process Regulation Of Smooth Muscle Contraction Regulation Of Vasoconstriction Positive Regulation Of Actin Filament Bundle Assembly Positive Regulation Of Protein Metabolic Process Regulation Of Focal Adhesion Assembly Angiotensin-mediated Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?