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MCF2
Gene Name
MCF.2 cell line derived transforming sequence
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytosol
Cytoskeleton
Membrane
Extracellular Vesicular Exosome
Molecular Function
Rho Guanyl-nucleotide Exchange Factor Activity
Protein Binding
Biological Process
Small GTPase Mediated Signal Transduction
Dendrite Development
Positive Regulation Of Rho GTPase Activity
Positive Regulation Of Apoptotic Process
Neurotrophin TRK Receptor Signaling Pathway
Regulation Of Small GTPase Mediated Signal Transduction
Apoptotic Signaling Pathway
Pathways
Rho GTPase cycle
Signaling by GPCR
GPCR downstream signaling
Signalling by NGF
Cell death signalling via NRAGE, NRIF and NADE
Signaling by Rho GTPases
NRAGE signals death through JNK
G alpha (12/13) signalling events
p75 NTR receptor-mediated signalling
Drugs
Diseases
GWAS
Protein-protein Interactions
9 interactors:
CDC42
GNA13
GNAI2
GNB1
HSP90AA1
RHOA
RHOG
STUB1
TNK2
Entrez ID
4168
HPRD ID
02406
Ensembl ID
ENSG00000101977
Uniprot IDs
B2R9S6
P10911
PDB IDs
Enriched GO Terms of Interacting Partners
?
Blood Coagulation
Hemostasis
Platelet Activation
Regulation Of Body Fluid Levels
Wound Healing
Small GTPase Mediated Signal Transduction
Response To Stress
Response To Wounding
Intracellular Signal Transduction
Cell Surface Receptor Signaling Pathway
Ras Protein Signal Transduction
Rho Protein Signal Transduction
Signal Transduction
Cell Activation
Signaling
Cell Communication
Regulation Of Catalytic Activity
Movement Of Cell Or Subcellular Component
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Axon Guidance
Enzyme Linked Receptor Protein Signaling Pathway
Cellular Response To Stimulus
Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway
G-protein Coupled Acetylcholine Receptor Signaling Pathway
Response To External Stimulus
G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Regulation Of Cellular Component Organization
Axonogenesis
Positive Regulation Of Metabolic Process
Axon Development
Cell Morphogenesis Involved In Neuron Differentiation
Locomotion
Chemotaxis
Neuron Projection Morphogenesis
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Response To Stimulus
Substantia Nigra Development
Cell Morphogenesis Involved In Differentiation
Regulation Of Cell Proliferation
Positive Regulation Of Cytokinesis
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Catalytic Activity
Neuron Projection Development
Regulation Of Signal Transduction
Cell Migration
Cell Projection Morphogenesis
Positive Regulation Of Cellular Component Biogenesis
Neural Nucleus Development
Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway
Cell Part Morphogenesis
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antigenic
bage
dbl
eso
exploit
fibrous
gage
gca
gcas
germ
histiocytoma
knew
lage
liposarcoma
mage
monophasic
msp
myxoid
ny
oligonucleotide
prame
proto
round
sarcoma
ssx
ssx2
sts
synovial
testis