KRT83 and PLEKHN1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRT83	PLEKHN1
Description		keratin 83	pleckstrin homology domain containing N1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytosol Intermediate Filament Keratin Filament	Mitochondrion Cytosol Cytoskeleton Plasma Membrane Membrane Mitochondrial Membrane
	Molecular Function	Protein Binding Structural Constituent Of Skin Epidermis	Phosphatidylserine Binding Protein Binding Phosphatidic Acid Binding Cardiolipin Binding Phosphatidylinositol Phosphate Binding
	Biological Process	Epidermis Development Keratinization Hair Cycle Intermediate Filament Organization	Response To Hypoxia Positive Regulation Of Apoptotic Process 3'-UTR-mediated MRNA Destabilization
Pathways		Keratinization Formation of the cornified envelope
Drugs
Diseases		Monilethrix
GWAS			Height ( 31562340) Parkinson's disease ( 26227905)
Interacting Genes		42 interacting genes: ADAM12 ANKS1A C11orf87 CEP57 CREB5 CYSRT1 DSCAM GEM GNE GSTP1 HOXA1 KRT15 KRT16 KRT19 KRT25 KRT27 KRT31 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT39 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP13-3 KRTAP3-3 KRTAP6-2 MEOX2 NBPF19 NOTCH2NLA NRF1 OIP5 PITX1 PLEKHN1 POU4F2 ZDHHC1	42 interacting genes: ABI2 AKAP8L ARID5A ATXN1 CBY2 CYSRT1 FHL5 HOXA1 KRT31 KRT36 KRT83 KRTAP1-3 KRTAP19-6 KRTAP6-2 LPXN LZTS2 MTUS2 NBPF19 NFKBID NOTCH2NLA PDLIM7 PIH1D1 PPM1J PPP1R16B PRICKLE4 PRKAA2 REL RFX6 SAXO4 SORBS3 SSC4D TAX1BP1 TCF4 TP53BP2 TRAF1 TRIM27 TRIP6 USP54 WWOX ZC4H2 ZNF438 ZRANB1
Entrez ID		3889	84069
HPRD ID		09097	13190
Ensembl ID		ENSG00000170523	ENSG00000187583
Uniprot IDs		P78385	Q494U1
PDB IDs
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Molecule Activity Morphogenesis Of An Epithelium Epithelial Cell Differentiation Tissue Morphogenesis Supramolecular Fiber Organization Anatomical Structure Morphogenesis Cytoskeleton Organization Cytoskeleton Cellular Developmental Process Cytosol Hair Cycle Extracellular Exosome Cell Differentiation Epidermis Development Developmental Process Structural Constituent Of Cytoskeleton Tissue Development Organelle Organization	Intermediate Filament Structural Constituent Of Skin Epidermis Keratin Filament
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