KRT83 and ZDHHC1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRT83	ZDHHC1
Description		keratin 83	zDHHC palmitoyltransferase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytosol Intermediate Filament Keratin Filament	Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Endosome Membrane Membrane Extracellular Exosome
	Molecular Function	Protein Binding Structural Constituent Of Skin Epidermis	DNA Binding Protein Binding Palmitoyltransferase Activity Transferase Activity Acyltransferase Activity Protein-cysteine S-palmitoyltransferase Activity
	Biological Process	Epidermis Development Keratinization Hair Cycle Intermediate Filament Organization	Positive Regulation Of Defense Response To Virus By Host Protein Targeting To Membrane NLRP3 Inflammasome Complex Assembly Antiviral Innate Immune Response Positive Regulation Of NLRP3 Inflammasome Complex Assembly
Pathways		Keratinization Formation of the cornified envelope
Drugs
Diseases		Monilethrix
GWAS			Body size at age 10 ( 32376654) Bone mineral density ( 31790847) Empathy quotient ( 29527006) Refractive error ( 32231278) Waist-to-hip ratio adjusted for body mass index ( 28430825)
Interacting Genes		42 interacting genes: ADAM12 ANKS1A C11orf87 CEP57 CREB5 CYSRT1 DSCAM GEM GNE GSTP1 HOXA1 KRT15 KRT16 KRT19 KRT25 KRT27 KRT31 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT39 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP13-3 KRTAP3-3 KRTAP6-2 MEOX2 NBPF19 NOTCH2NLA NRF1 OIP5 PITX1 PLEKHN1 POU4F2 ZDHHC1	18 interacting genes: CYSRT1 GOPC KRT31 KRT34 KRT83 KRTAP1-1 KRTAP1-3 KRTAP10-8 KRTAP12-2 KRTAP12-3 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP9-2 KRTAP9-3 MDFI NBPF19 NOTCH2NLA
Entrez ID		3889	29800
HPRD ID		09097	15707
Ensembl ID		ENSG00000170523	ENSG00000159714
Uniprot IDs		P78385	I3L202 Q8WTX9
PDB IDs
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Molecule Activity Morphogenesis Of An Epithelium Epithelial Cell Differentiation Tissue Morphogenesis Supramolecular Fiber Organization Anatomical Structure Morphogenesis Cytoskeleton Organization Cytoskeleton Cellular Developmental Process Cytosol Hair Cycle Extracellular Exosome Cell Differentiation Epidermis Development Developmental Process Structural Constituent Of Cytoskeleton Tissue Development Organelle Organization	Intermediate Filament Keratin Filament Structural Constituent Of Skin Epidermis Epidermis Development Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Cytosol Negative Regulation Of Anion Channel Activity Identical Protein Binding
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