TMEM218 and TM4SF18

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM218	TM4SF18
Description		transmembrane protein 218	transmembrane 4 L six family member 18
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cilium Membrane Cell Projection	Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS		Breast cancer (survival) ( 25890600) Familial lung adenocarcinoma ( 29924316)
Interacting Genes		75 interacting genes: APH1A AQP2 AQP6 ARL13B ASZ1 ATP6V0E1 BSCL2 CD300A CD53 CD79A CLDN2 CLEC10A CLEC17A CPLX4 CREB3L1 CTLA4 DAGLA EBP ELOVL2 ELOVL4 EMP1 ERGIC3 FAM209A FCER1G FFAR2 FRMD3 GDAP1 GJB1 GJB4 GJB6 GPR152 GPR61 GPX8 HSD17B13 IFNGR2 KCNJ6 KCNK5 KIR2DL3 LDLRAD1 LHFPL5 LMNA LSMEM2 MFF MS4A3 MTIF3 MUC1 NPFFR2 PCNA PDCD1LG2 PIK3IP1 PLEKHO1 PSCA RETREG3 SAR1A SDC3 SLC10A4 SLC10A6 SLC18A1 SMIM3 SSMEM1 TM4SF18 TMED8 TMEM106C TMEM182 TMEM207 TMEM234 TMEM31 TMEM45B TMEM52B TMEM88 TMPRSS2 TRHR TSPAN12 TSPAN18 VSIR	33 interacting genes: BNIP3 CLDN19 CLEC2D CXCL9 CYB561 CYB561A3 EFNA5 EMP3 FXYD6 GIMAP5 IER3IP1 ITGB2 LAT LHFPL5 MAL MS4A13 MS4A3 NIPAL4 NSG1 PMP22 RPRM SERP2 SLC30A2 SLC39A9 SMIM3 STRIT1 TEX264 TMEM218 TRARG1 TREX1 UBE2J1 UNC93B1 VAMP5
Entrez ID		219854	116441
HPRD ID		19054	14018
Ensembl ID		ENSG00000150433	ENSG00000163762
Uniprot IDs		A2RU14 E9PI23	Q96CE8
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Plasma Membrane Protein Binding Connexin Complex Regulation Of Myoblast Fusion Gap Junction Channel Activity Gap Junction Bile Acid:sodium Symporter Activity Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongase Activity Fatty Acid Elongation, Polyunsaturated Fatty Acid Fucose Binding Gap Junction-mediated Intercellular Transport Renal Water Transport Gap Junction Assembly Fatty Acid Elongation, Saturated Fatty Acid	Membrane T Cell Antigen Processing And Presentation Membrane Raft Distribution Membrane Raft Localization Bleb Assembly Schmidt-Lanterman Incisure Establishment Of Protein Localization To Plasma Membrane Endosome To Plasma Membrane Protein Transport Endoplasmic Reticulum
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