TMEM218 and TMEM52B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM218	TMEM52B
Description		transmembrane protein 218	transmembrane protein 52B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cilium Membrane Cell Projection	Membrane Extracellular Exosome
	Molecular Function	Protein Binding	Protein Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS		Breast cancer (survival) ( 25890600) Familial lung adenocarcinoma ( 29924316)
Interacting Genes		75 interacting genes: APH1A AQP2 AQP6 ARL13B ASZ1 ATP6V0E1 BSCL2 CD300A CD53 CD79A CLDN2 CLEC10A CLEC17A CPLX4 CREB3L1 CTLA4 DAGLA EBP ELOVL2 ELOVL4 EMP1 ERGIC3 FAM209A FCER1G FFAR2 FRMD3 GDAP1 GJB1 GJB4 GJB6 GPR152 GPR61 GPX8 HSD17B13 IFNGR2 KCNJ6 KCNK5 KIR2DL3 LDLRAD1 LHFPL5 LMNA LSMEM2 MFF MS4A3 MTIF3 MUC1 NPFFR2 PCNA PDCD1LG2 PIK3IP1 PLEKHO1 PSCA RETREG3 SAR1A SDC3 SLC10A4 SLC10A6 SLC18A1 SMIM3 SSMEM1 TM4SF18 TMED8 TMEM106C TMEM182 TMEM207 TMEM234 TMEM31 TMEM45B TMEM52B TMEM88 TMPRSS2 TRHR TSPAN12 TSPAN18 VSIR	70 interacting genes: ALG3 APOD APOL2 APOL3 BET1 BTN2A2 C1GALT1 C3orf52 CLDN19 CLDN4 CNIH1 CNIH3 CRYAA CSGALNACT2 DNAJC30 EMD FXYD3 GAST GPR25 GPR37L1 IGFBP5 INSIG2 ITGAM JAGN1 LHFPL5 LPAR3 LTC4S MAL MARCHF2 MIP MS4A13 NINJ2 NRM NSG1 ORMDL1 PEDS1-UBE2V1 PGAP2 PLN PLP1 RTP2 SEC22A SERP1 SLC30A2 SLC30A8 SLC35A4 SLC35B4 SLC38A7 SMIM1 TF TMEM100 TMEM107 TMEM109 TMEM128 TMEM147 TMEM14C TMEM203 TMEM218 TMEM267 TMEM50B TMEM54 TMEM60 TMEM86B TMEM97 TMUB2 TRAM1L1 TRARG1 VAMP3 VAMP5 YIPF6 ZDHHC15
Entrez ID		219854	120939
HPRD ID		19054	08709
Ensembl ID		ENSG00000150433	ENSG00000165685
Uniprot IDs		A2RU14 E9PI23	Q4KMG9
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Plasma Membrane Protein Binding Connexin Complex Regulation Of Myoblast Fusion Gap Junction Channel Activity Gap Junction Bile Acid:sodium Symporter Activity Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongase Activity Fatty Acid Elongation, Polyunsaturated Fatty Acid Fucose Binding Gap Junction-mediated Intercellular Transport Renal Water Transport Gap Junction Assembly Fatty Acid Elongation, Saturated Fatty Acid	Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Establishment Of Protein Localization To Membrane Protein Binding Golgi Membrane Localization Within Membrane Establishment Of Protein Localization To Plasma Membrane Cellular Localization Protein Insertion Into Membrane Establishment Of Protein Localization Zinc:proton Antiporter Activity Nuclear Outer Membrane Protein Localization To Membrane Paracellular Transport Protein Localization To Postsynapse Lipid Binding SNAP Receptor Activity Transmembrane Transport Structural Constituent Of Myelin Sheath Zinc Ion Import Into Organelle Intestinal Epithelial Cell Development Pyrimidine Nucleotide-sugar Transmembrane Transport Vesicle-mediated Transport
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