KRAS and RAF1

  • Number of citations of the paper that reports this interaction (PMID 9446616)
  • 12
  • Data Source:
  • HPRD (in vitro)

KRAS

RAF1

Gene Name Kirsten rat sarcoma viral oncogene homolog Raf-1 proto-oncogene, serine/threonine kinase
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 35 interactors: ADH6 APP ARAF BCL2 CALM1 CCT7 DDX47 DDX50 DNAJA3 EEF1A1 EGLN1 EPB42 FNTA FNTB HNRNPC IGSF21 LPAR1 MDFI PDE4DIP PGGT1B PIK3CA PIK3CG PIK3R2 PSMA3 RAF1 RALGDS RAP1GDS1 RASGRF2 RASGRP2 RASSF2 RASSF5 RBPMS RGL2 SHOC2 ZDHHC17 123 interactors: ADCY6 AGTR1 AKT1 AR ARRB2 BAD BAG1 BCL2 BCL2L1 BCL6 BIRC2 BIRC3 BRAF CCT3 CDC25A CFLAR CNKSR1 COPS3 COPS7A CPS1 DCAF8 DMPK EFEMP1 ERBB2IP FYCO1 FYN GNB2 GNG4 GRB10 HRAS HSP90AA1 HSPA4 HSPA8 IL2RB INSR INTS10 JAK1 JAK2 KRAS KRT18 KRT8 KSR1 KSR2 LCK LRPAP1 MAP2K1 MAP2K2 MAP3K1 MAP3K5 MAPK1 MAPK3 MAPK7 MAPK8 MAPK8IP3 MRAS MYBPC1 MYC NEDD4 NPLOC4 NR3C1 NRAS NUDT14 OIP5 PACSIN3 PAK1 PAK2 PAK3 PBK PDGFRB PEBP1 PEBP4 PEX5L PHB PHKA2 PIN1 PKM PPP1CC PPP2CB PRKAA1 PRKACA PRKAR1A PRKCA PRKCD PRKCE PRKCZ PRKG1 PRPF6 PURA RANBP9 RAP1A RAP2A RASD2 RB1 RBBP8 RBL2 RFXANK RHEB RRAS RRAS2 RSU1 SHOC2 SPRY2 SPRY4 SRC STK26 STK3 STUB1 TBXA2R TIMM50 TMEM70 TSC22D3 UBC UBE2D2 VAV1 VDAC1 XIAP YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ YY1
Entrez ID 3845 5894
HPRD ID 01817 01265
Ensembl ID ENSG00000133703 ENSG00000132155
Uniprot IDs L7RSL8 P01116 B4E0X2 L7RRS6 P04049
PDB IDs 1D8D 1D8E 1KZO 1KZP 3GFT 4DSN 4DSO 4EPR 4EPT 4EPV 4EPW 4EPX 4EPY 1C1Y 1FAQ 1FAR 1GUA 1RFA 3CU8 3IQJ 3IQU 3IQV 3KUC 3KUD 3NKX 3O8I 3OMV 4FJ3 4G0N 4G3X 4IEA 4IHL
Enriched GO Terms of Interacting Partners?
Tagcloud ?
bitransgenic  coexpressed  coexpression  contributions  cooperate  crypt  d11137  dedifferentiation  describing  dysplastic  enterocyte  enterocytes  expresses  geographically  oncoproteins  organized  p107  perturb  postmitotic  reenter  retains  simian  sv40  tag  tagd11137  tagwt  val  val12  villus 
cot  densitometry  erk2  hog  immunoreactivities  jnks  kinases  mapkapk2  mapks  mek1  mekkl  mkk3  mlk3  mos  myocytes  pak2  pakl  phenomena  probed  proliferate  proto  rafb  resist  rsk1  rsk2  sekl  tpl  ventricle  ventricles 
Tagcloud (Difference) ?
bitransgenic  coexpressed  coexpression  contributions  cooperate  crypt  d11137  dedifferentiation  describing  dysplastic  enterocyte  enterocytes  expresses  geographically  oncoproteins  organized  p107  perturb  postmitotic  reenter  retains  simian  sv40  tag  tagd11137  tagwt  val  val12  villus 
cot  densitometry  erk2  hog  immunoreactivities  jnks  kinases  mapkapk2  mapks  mek1  mekkl  mkk3  mlk3  mos  myocytes  pak2  pakl  phenomena  probed  proliferate  proto  rafb  resist  rsk1  rsk2  sekl  tpl  ventricle  ventricles 
Tagcloud (Intersection) ?