KCNA10 and MAL

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KCNA10	MAL
Description		potassium voltage-gated channel subfamily A member 10	mal, T cell differentiation protein (MAL blood group)
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Voltage-gated Potassium Channel Complex Membrane Monoatomic Ion Channel Complex	Endoplasmic Reticulum Plasma Membrane Membrane Apical Plasma Membrane Schmidt-Lanterman Incisure Plasma Membrane Raft Membrane Raft Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane
	Molecular Function	Monoatomic Ion Channel Activity Intracellularly Cyclic Nucleotide-activated Monoatomic Cation Channel Activity Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Potassium Channel Activity Protein Binding	Protein Binding Lipid Binding Peptidase Activator Activity Involved In Apoptotic Process Structural Constituent Of Myelin Sheath
	Biological Process	Action Potential Monoatomic Ion Transport Potassium Ion Transport Monoatomic Ion Transmembrane Transport Protein Homooligomerization Transmembrane Transport Potassium Ion Transmembrane Transport	Membrane Raft Polarization Protein Localization To Paranode Region Of Axon Apoptotic Process Central Nervous System Development Central Nervous System Myelination Cell Differentiation Myelination Apical Protein Localization Protein Insertion Into Plasma Membrane Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Pathways		Voltage gated Potassium channels
Drugs		Enflurane Promethazine Miconazole Dalfampridine
Diseases
GWAS		Bitter taste perception (phenylthiocarbamide) in obesity with metabolic syndrome ( 31005965) Response to bupropion in depression ( 27622933)
Interacting Genes		6 interacting genes: DOLK KCNA1 MAL POMP SGTA TMBIM6	81 interacting genes: AMHR2 AQP6 BCL2L13 BTN2A1 CALN1 CD300LG CD3G CD40 CD53 CD69 CLDN14 CLDN20 CLDN7 CLDN9 CLEC4C CLSTN3 CPLX4 CREB3L1 CXADR DAGLA EDA EMP1 EVI2A FAM209A FCRL2 FIBCD1 FNDC9 GJA8 GJB1 GPR152 GRAMD1A GSG1L HIBADH IL10RA IL20RB JAML KCNA1 KCNA10 KCNMB4 KLRC1 LDLRAD1 LMAN2L LMNA LRRC25 LRTM1 LSMEM1 MC4R MS4A4A MYD88 NCAPH2 NKAIN4 NPDC1 OPRM1 PERP PLA2G10 PRRT1 PTPRN RAMP1 SDC4 SGCB SHISA3 SHISA4 SLC10A1 SLC35H1 SMIM3 SPINT1 STX1A SYNDIG1 TEX29 TIGIT TM4SF18 TMEM106C TMEM174 TMEM207 TMEM213 TMEM248 TMEM30A TMEM52B TNFSF14 TSPO2 USP7
Entrez ID		3744	4118
HPRD ID		03882	01789
Ensembl ID		ENSG00000143105	ENSG00000172005
Uniprot IDs		Q16322	P21145
PDB IDs
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Protein Insertion Into Plasma Membrane Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane Protein Insertion Into Membrane Negative Regulation Of Response To Endoplasmic Reticulum Stress Neuron Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Dolichol Kinase Activity Regulation Of Response To Endoplasmic Reticulum Stress TRC Complex Endoribonuclease Inhibitor Activity Detection Of Mechanical Stimulus Involved In Sensory Perception Of Touch Protein Localization To Paranode Region Of Axon Membrane Raft Polarization BAT3 Complex Binding Dolichol Phosphate Mannose Biosynthetic Process Dolichyl Monophosphate Biosynthetic Process Dolichyl Diphosphate Biosynthetic Process Neuronal Signal Transduction Cellular Response To Magnesium Ion Membrane Raft Distribution Establishment Of Protein Localization To Membrane Peptidase Activator Activity Involved In Apoptotic Process Negative Regulation Of ERAD Pathway Negative Regulation Of Calcium Ion Transport Into Cytosol Negative Regulation Of Hypoxia-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of IRE1-mediated Unfolded Protein Response Membrane Raft Localization Response To Endoplasmic Reticulum Stress Juxtaparanode Region Of Axon Paranode Region Of Axon Magnesium Ion Homeostasis Detection Of Mechanical Stimulus Involved In Sensory Perception Of Pain Membrane Protein Localization To Axon Schmidt-Lanterman Incisure Structural Constituent Of Myelin Sheath Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Central Nervous System Myelination Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Negative Regulation Of Cellular Response To Hypoxia IRE1-mediated Unfolded Protein Response Negative Regulation Of Immunoglobulin Production Proteasome Assembly Apical Protein Localization Tail-anchored Membrane Protein Insertion Into ER Membrane Regulation Of IRE1-mediated Unfolded Protein Response Negative Regulation Of Cytosolic Calcium Ion Concentration Response To Magnesium Ion Startle Response Positive Regulation Of ERAD Pathway	Membrane Plasma Membrane Protein Binding Gamma-delta T Cell Activation Anchoring Junction Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Postsynaptic Density Membrane Cell-cell Junction Organization Bicellular Tight Junction Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell Junction Organization Bicellular Tight Junction Assembly Tight Junction Assembly Tight Junction Organization Structural Molecule Activity Cell-cell Junction Assembly Leukocyte Activation
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?