KCNA10

Name	potassium voltage-gated channel subfamily A member 10
Structure	No pdb structure
Interactors	6 interactors: DOLK KCNA1 MAL POMP SGTA TMBIM6
GO Annotations	Cellular Component	Plasma Membrane Voltage-gated Potassium Channel Complex Membrane Monoatomic Ion Channel Complex
	Molecular Function	Monoatomic Ion Channel Activity Intracellularly Cyclic Nucleotide-activated Monoatomic Cation Channel Activity Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Potassium Channel Activity Protein Binding
	Biological Process	Action Potential Monoatomic Ion Transport Potassium Ion Transport Monoatomic Ion Transmembrane Transport Protein Homooligomerization Transmembrane Transport Potassium Ion Transmembrane Transport
Pathways	Voltage gated Potassium channels
Drugs	Enflurane Promethazine Miconazole Dalfampridine
GWAS	Bitter taste perception (phenylthiocarbamide) in obesity with metabolic syndrome ( 31005965 ) Response to bupropion in depression ( 27622933 )
Entrez ID	3744
HPRD ID	03882
Ensembl ID	ENSG00000143105
Uniprot IDs	Q16322
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Endoplasmic Reticulum Protein Insertion Into Plasma Membrane Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane Protein Insertion Into Membrane Negative Regulation Of Response To Endoplasmic Reticulum Stress Neuron Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Dolichol Kinase Activity Regulation Of Response To Endoplasmic Reticulum Stress TRC Complex Endoribonuclease Inhibitor Activity Detection Of Mechanical Stimulus Involved In Sensory Perception Of Touch Protein Localization To Paranode Region Of Axon Membrane Raft Polarization BAT3 Complex Binding Dolichol Phosphate Mannose Biosynthetic Process Dolichyl Monophosphate Biosynthetic Process Dolichyl Diphosphate Biosynthetic Process Neuronal Signal Transduction Cellular Response To Magnesium Ion Membrane Raft Distribution Establishment Of Protein Localization To Membrane Peptidase Activator Activity Involved In Apoptotic Process Negative Regulation Of ERAD Pathway Negative Regulation Of Calcium Ion Transport Into Cytosol Negative Regulation Of Hypoxia-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of IRE1-mediated Unfolded Protein Response Membrane Raft Localization Response To Endoplasmic Reticulum Stress Juxtaparanode Region Of Axon Paranode Region Of Axon Magnesium Ion Homeostasis Detection Of Mechanical Stimulus Involved In Sensory Perception Of Pain Membrane Protein Localization To Axon Schmidt-Lanterman Incisure Structural Constituent Of Myelin Sheath Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Central Nervous System Myelination Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Negative Regulation Of Cellular Response To Hypoxia IRE1-mediated Unfolded Protein Response Negative Regulation Of Immunoglobulin Production Proteasome Assembly Apical Protein Localization Tail-anchored Membrane Protein Insertion Into ER Membrane Regulation Of IRE1-mediated Unfolded Protein Response Negative Regulation Of Cytosolic Calcium Ion Concentration Response To Magnesium Ion Startle Response Positive Regulation Of ERAD Pathway