INHBB and INHBC

Number of citations of the paper that reports this interaction (PMID 11134153)
10

Data Source:
HPRD (in vitro)

		INHBB	INHBC
Gene Name		inhibin, beta B	inhibin, beta C
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Perinuclear Region Of Cytoplasm	Extracellular Region Extracellular Space Extracellular Vesicular Exosome
	Molecular Function	Cytokine Activity Transforming Growth Factor Beta Receptor Binding Hormone Activity Protein Binding Growth Factor Activity Protein Homodimerization Activity Host Cell Surface Receptor Binding	Cytokine Activity Transforming Growth Factor Beta Receptor Binding Hormone Activity Growth Factor Activity
	Biological Process	Ovarian Follicle Development Defense Response Cellular Response To Starvation Response To Mechanical Stimulus Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Cell Differentiation Cellular Response To Insulin Stimulus Activin Receptor Signaling Pathway Growth Regulation Of Apoptotic Process Regulation Of MAPK Cascade Cellular Response To Leptin Stimulus Fat Cell Differentiation Negative Regulation Of Insulin Secretion Positive Regulation Of Follicle-stimulating Hormone Secretion Negative Regulation Of Follicle-stimulating Hormone Secretion Negative Regulation Of Hepatocyte Growth Factor Biosynthetic Process Cell Development Oocyte Development Positive Regulation Of Ovulation SMAD Protein Signal Transduction Positive Regulation Of Apoptotic Signaling Pathway	Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Growth Regulation Of Apoptotic Process Regulation Of MAPK Cascade Cell Development SMAD Protein Signal Transduction
Pathways		Antagonism of Activin by Follistatin Peptide hormone metabolism Glycoprotein hormones Signaling by Activin Peptide hormone biosynthesis	Peptide hormone metabolism Glycoprotein hormones Peptide hormone biosynthesis
Drugs
Diseases
GWAS		Age-related macular degeneration ( 23326517) Breast size ( 22747683) Obesity ( 21552555) Urate levels ( 23263486)	Urate levels ( 20884846 23263486)
Protein-Protein Interactions		10 interactors: ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B FNTA IGSF1 INHA INHBA INHBC	6 interactors: ACVR1 ACVR1B ACVR2A ACVR2B INHBA INHBB
Entrez ID		3625	3626
HPRD ID		00934	03136
Ensembl ID		ENSG00000163083	ENSG00000175189
Uniprot IDs		P09529	P55103
PDB IDs
Enriched GO Terms of Interacting Partners?		Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Activin Receptor Signaling Pathway Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of Pathway-restricted SMAD Protein Phosphorylation Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Activin Receptor Signaling Pathway Positive Regulation Of Protein Modification Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Activin Receptor Signaling Pathway Positive Regulation Of Protein Phosphorylation Regulation Of Protein Metabolic Process Positive Regulation Of Phosphorylation Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Phosphorylation Signal Transduction By Phosphorylation Positive Regulation Of Erythrocyte Differentiation Regulation Of Signaling Cell Surface Receptor Signaling Pathway Positive Regulation Of Signal Transduction Regulation Of Phosphorylation Positive Regulation Of Metabolic Process Mesoderm Development Signal Transduction Regulation Of Phosphorus Metabolic Process Regulation Of Erythrocyte Differentiation Positive Regulation Of Bone Mineralization Regulation Of Myeloid Cell Differentiation Signaling Positive Regulation Of Biomineral Tissue Development Cell Communication Gastrulation Negative Regulation Of Follicle-stimulating Hormone Secretion Positive Regulation Of Follicle-stimulating Hormone Secretion Gastrulation With Mouth Forming Second Regulation Of Signal Transduction Regulation Of Follicle-stimulating Hormone Secretion SMAD Protein Signal Transduction Development Of Primary Sexual Characteristics Negative Regulation Of Hormone Secretion Hemoglobin Biosynthetic Process Cellular Response To Stimulus Regulation Of Bone Mineralization Positive Regulation Of Osteoblast Differentiation Negative Regulation Of Gonadotropin Secretion Positive Regulation Of Myeloid Cell Differentiation BMP Signaling Pathway Sex Differentiation Negative Regulation Of B Cell Differentiation	Activin Receptor Signaling Pathway Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of Pathway-restricted SMAD Protein Phosphorylation Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Activin Receptor Signaling Pathway Positive Regulation Of Activin Receptor Signaling Pathway Positive Regulation Of Protein Phosphorylation Positive Regulation Of Phosphorylation Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Protein Modification Process Regulation Of Protein Phosphorylation Positive Regulation Of Erythrocyte Differentiation Positive Regulation Of Cellular Protein Metabolic Process Mesoderm Development Positive Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction Regulation Of Phosphorylation Gastrulation Regulation Of Erythrocyte Differentiation Regulation Of Phosphorus Metabolic Process Positive Regulation Of Bone Mineralization Positive Regulation Of Biomineral Tissue Development Development Of Primary Sexual Characteristics Developmental Process Involved In Reproduction Gastrulation With Mouth Forming Second Negative Regulation Of Follicle-stimulating Hormone Secretion Positive Regulation Of Follicle-stimulating Hormone Secretion Signal Transduction By Phosphorylation Sex Differentiation Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cell Differentiation Positive Regulation Of Ovulation Regulation Of Follicle-stimulating Hormone Secretion Regulation Of Bone Mineralization Positive Regulation Of Osteoblast Differentiation Positive Regulation Of Myeloid Cell Differentiation BMP Signaling Pathway Regulation Of Protein Metabolic Process Negative Regulation Of Gonadotropin Secretion Positive Regulation Of Ossification Embryo Development Positive Regulation Of Cellular Metabolic Process Determination Of Left/right Symmetry Determination Of Bilateral Symmetry Development Of Primary Female Sexual Characteristics Regulation Of Signal Transduction Reproductive Process Regulation Of Osteoblast Differentiation Organ Development Regulation Of Signaling
Tagcloud ?		actb activin activins canonical canonically comprise concert cord cords incompletely ligands maturation maturing morphogenetic myelin myelination numbers oligodendrocyte oligodendrocytes olp olps persistently recover smad3 smads specified spinal tgfbeta tgfbeta1	aetiology ancestry college direction equivocal european europeans gckr genotyped gout hlf inconsistency loci maaori maf meeting obvious opposing pacific pdzk1 polynesian prkag2 replicated rheumatology sizes slc16a9 slc22a11 urate zealand
Tagcloud (Difference) ?		actb activin activins canonical canonically comprise concert cord cords incompletely ligands maturation maturing morphogenetic myelin myelination numbers oligodendrocyte oligodendrocytes olp olps persistently recover smad3 smads specified spinal tgfbeta tgfbeta1	aetiology ancestry college direction equivocal european europeans gckr genotyped gout hlf inconsistency loci maaori maf meeting obvious opposing pacific pdzk1 polynesian prkag2 replicated rheumatology sizes slc16a9 slc22a11 urate zealand
Tagcloud (Intersection) ?