INHBC

Description		inhibin subunit beta C
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	Cytokine Activity Transforming Growth Factor Beta Receptor Binding Hormone Activity Growth Factor Activity
	Biological Process	Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway
Pathways		Glycoprotein hormones
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Aspartate aminotransferase levels ( 33547301) Asthma ( 31619474) Blood protein levels ( 30072576) Body mass index and HDL-C (pairwise) ( 33619380) Body mass index and triglycerides (pairwise) ( 33619380) Chronic kidney disease ( 29124443) Chronotype ( 30696823) Estimated glomerular filtration rate in non-diabetics ( 31451708) Fasting glucose ( 34059833) Glomerular filtration rate (creatinine) ( 26831199) Gout ( 33832965) HDL cholesterol levels ( 30698716 32203549) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Hemoglobin levels ( 32327693) Serum uric acid levels ( 30993211) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Urate levels ( 31985003 31578528 20884846 23263486) Urate levels in overweight individuals ( 25811787)
Interacting Genes		6 interacting genes: ACVR1 ACVR1B ACVR2A ACVR2B INHBA INHBB
Entrez ID		3626
HPRD ID		03136
Ensembl ID		ENSG00000175189
Uniprot IDs		P55103
PDB IDs
Enriched GO Terms of Interacting Partners?		Activin Receptor Signaling Pathway Activin Receptor Complex Transmembrane Receptor Protein Serine/threonine Kinase Activity Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Activin Binding Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Activin Receptor Signaling Pathway Activin Receptor Activity Positive Regulation Of Activin Receptor Signaling Pathway Growth Factor Binding Activin Receptor Activity, Type I Enzyme-linked Receptor Protein Signaling Pathway Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Gastrulation With Mouth Forming Second Regulation Of Ossification Positive Regulation Of Ovulation Positive Regulation Of Erythrocyte Differentiation Positive Regulation Of SMAD Protein Signal Transduction Positive Regulation Of Bone Mineralization Negative Regulation Of Ossification Activin Receptor Activity, Type II Negative Regulation Of Follicle-stimulating Hormone Secretion Gastrulation Positive Regulation Of Biomineral Tissue Development Regulation Of Erythrocyte Differentiation Positive Regulation Of Ossification Inhibin Binding Positive Regulation Of Signal Transduction Mesoderm Development Positive Regulation Of Multicellular Organismal Process Cellular Response To Growth Factor Stimulus Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of SMAD Protein Signal Transduction Positive Regulation Of Osteoblast Differentiation Regulation Of Follicle-stimulating Hormone Secretion Positive Regulation Of Follicle-stimulating Hormone Secretion Response To Growth Factor Regulation Of Bone Mineralization Positive Regulation Of Reproductive Process Positive Regulation Of Cell Differentiation BMP Signaling Pathway Cell Surface Receptor Signaling Pathway BMP Receptor Activity Negative Regulation Of Gonadotropin Secretion Determination Of Bilateral Symmetry Determination Of Left/right Symmetry Odontogenesis Protein Serine/threonine Kinase Activity
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