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INHA and TGFBR3
Number of citations of the paper that reports this interaction (PubMedID
10746731
)
0
Data Source:
HPRD
(in vivo)
INHA
TGFBR3
Description
inhibin subunit alpha
transforming growth factor beta receptor 3
Image
No pdb structure
GO Annotations
Cellular Component
Photoreceptor Outer Segment
Photoreceptor Inner Segment
Extracellular Region
Extracellular Space
Inhibin-betaglycan-ActRII Complex
Neuronal Cell Body
Inhibin A Complex
Inhibin B Complex
Extracellular Region
Extracellular Space
Cytosol
Plasma Membrane
External Side Of Plasma Membrane
Cell Surface
Membrane
Basolateral Plasma Membrane
Inhibin-betaglycan-ActRII Complex
Receptor Complex
Extracellular Exosome
Cell Periphery
Molecular Function
Signaling Receptor Binding
Cytokine Activity
Hormone Activity
Protein Binding
Growth Factor Activity
Inhibin Binding
Protein-containing Complex Binding
Transmembrane Signaling Receptor Activity
Transforming Growth Factor Beta Receptor Activity
Type II Transforming Growth Factor Beta Receptor Binding
Transforming Growth Factor Beta Receptor Binding
Protein Binding
Glycosaminoglycan Binding
Heparin Binding
Coreceptor Activity
Fibroblast Growth Factor Binding
PDZ Domain Binding
BMP Binding
SMAD Binding
Activin Binding
Transforming Growth Factor Beta Binding
Transforming Growth Factor Beta Receptor Activity, Type III
Biological Process
Skeletal System Development
Ovarian Follicle Development
Signal Transduction
Cell Surface Receptor Signaling Pathway
Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway
Cell-cell Signaling
Male Gonad Development
Cell Differentiation
Erythrocyte Differentiation
Negative Regulation Of Type II Interferon Production
Regulation Of Cell Population Proliferation
Negative Regulation Of Phosphorylation
Hemoglobin Biosynthetic Process
Negative Regulation Of B Cell Differentiation
Negative Regulation Of Macrophage Differentiation
Negative Regulation Of Cell Cycle
Regulation Of Follicle-stimulating Hormone Secretion
Positive Regulation Of Follicle-stimulating Hormone Secretion
Negative Regulation Of Follicle-stimulating Hormone Secretion
System Development
Negative Regulation Of Multicellular Organismal Process
Regulation Of Cell Cycle
Response To Hypoxia
Epithelial To Mesenchymal Transition
Liver Development
Heart Morphogenesis
Muscular Septum Morphogenesis
Outflow Tract Morphogenesis
Ventricular Compact Myocardium Morphogenesis
Immune Response
Transforming Growth Factor Beta Receptor Signaling Pathway
Transforming Growth Factor Beta Receptor Complex Assembly
Positive Regulation Of Gene Expression
Cell Migration
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Cell Migration
BMP Signaling Pathway
Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Animal Organ Regeneration
Response To Follicle-stimulating Hormone
Response To Prostaglandin E
Response To Luteinizing Hormone
Intracellular Signal Transduction
Negative Regulation Of Canonical NF-kappaB Signal Transduction
Regulation Of JNK Cascade
Negative Regulation Of Epithelial Cell Proliferation
Ventricular Cardiac Muscle Tissue Morphogenesis
Cardiac Muscle Cell Proliferation
Positive Regulation Of Cardiac Muscle Cell Proliferation
Definitive Hemopoiesis
Cardiac Epithelial To Mesenchymal Transition
Definitive Erythrocyte Differentiation
Heart Trabecula Formation
Positive Regulation Of SMAD Protein Signal Transduction
Negative Regulation Of SMAD Protein Signal Transduction
Ventricular Septum Morphogenesis
Epicardium-derived Cardiac Fibroblast Cell Development
Vasculogenesis Involved In Coronary Vascular Morphogenesis
Heart Trabecula Morphogenesis
Secondary Palate Development
Protein-containing Complex Assembly
Regulation Of ERK1 And ERK2 Cascade
Cellular Response To Transforming Growth Factor Beta Stimulus
Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Negative Regulation Of Extracellular Matrix Assembly
Pathways
Signaling by Activin
Signaling by Activin
Signaling by BMP
Glycoprotein hormones
TGFBR3 regulates activin signaling
Signaling by Activin
Signaling by Activin
FGFR1b ligand binding and activation
FGFR1c ligand binding and activation
Signaling by BMP
TGF-beta receptor signaling activates SMADs
TGFBR3 PTM regulation
TGFBR3 regulates TGF-beta signaling
TGFBR3 expression
TGFBR3 regulates FGF2 signaling
TGFBR3 regulates activin signaling
Drugs
Diseases
Premature ovarian failure
GWAS
Appendicular lean mass (
33097823
)
Bone mineral density (
19249006
)
Carotid plaque burden (
28282560
)
dexamethasone sensitivity in B-cell precursor acute lymphoblastic leukaemia (
33002292
)
Gestational age at birth (maternal effect) (
28877031
)
Glaucoma (primary open-angle) (
33627673
25861811
)
HDL cholesterol change in response to fenofibrate in statin-treated type 2 diabetes (
28736931
)
Heel bone mineral density (
30598549
)
HOMA-B (corrected for HOMA-IR) (
30369944
)
Lung function (FEV1/FVC) (
30804560
28166213
)
Lung function (FVC) (
26635082
30804560
)
Metamizole-induced agranulocytosis or neutropenia (
33138277
)
Multiple sclerosis (
31604244
)
Optic disc area (
25631615
21307088
28073927
31798171
)
Optic disc parameters (
20548946
)
Optic disc size (
31809533
)
Optic nerve measurement (cup-to-disc ratio) (
28061514
)
Peak expiratory flow (
30804560
)
Pulse pressure (
30224653
)
QT interval (tricyclic/tetracyclic antidepressant use interaction) (
28039329
)
Type 2 diabetes (
23209189
)
Vertical cup-disc ratio (
31798171
28073927
25241763
)
Vertical cup-disc ratio (multi-trait analysis) (
31959993
)
Interacting Genes
5 interacting genes:
FST
INHBA
INHBB
SIAH1
TGFBR3
13 interacting genes:
ACVR2A
ARRB2
DYNLT4
ENG
GIPC1
INHA
INHBA
NRP1
SDC2
TGFB1
TGFB2
TGFB3
TGFBR2
Entrez ID
3623
7049
HPRD ID
00933
02846
Ensembl ID
ENSG00000123999
ENSG00000069702
Uniprot IDs
P05111
A0A0A8KWK3
Q03167
PDB IDs
7LBG
Enriched GO Terms of Interacting Partners
?
Cardiac Fibroblast Cell Development
Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway
Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway
Response To Gonadotropin
Positive Regulation Of Ovulation
Negative Regulation Of Follicle-stimulating Hormone Secretion
Regulation Of Follicle-stimulating Hormone Secretion
Positive Regulation Of Follicle-stimulating Hormone Secretion
Negative Regulation Of Gonadotropin Secretion
Activin Binding
Gonad Development
Positive Regulation Of Apoptotic Signaling Pathway
Response To Follicle-stimulating Hormone
Cellular Response To Cholesterol
Enzyme-linked Receptor Protein Signaling Pathway
Cellular Response To Sterol
Reproductive Structure Development
Response To Cholesterol
Cell Surface Receptor Signaling Pathway
Response To Ketone
Female Gonad Development
Activin Receptor Signaling Pathway
Developmental Process Involved In Reproduction
Response To Alcohol
Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Cell Differentiation
Response To Peptide Hormone
Positive Regulation Of SMAD Protein Signal Transduction
Cardiac Cell Development
Ovarian Follicle Development
Regulation Of Apoptotic Signaling Pathway
Cellular Developmental Process
Negative Regulation Of Hormone Secretion
Regulation Of SMAD Protein Signal Transduction
Regulation Of Signal Transduction
Reproductive Process
Erythrocyte Differentiation
Positive Regulation Of Reproductive Process
Roof Of Mouth Development
Hair Cycle Process
Animal Organ Development
BMP Signaling Pathway
Positive Regulation Of Apoptotic Process
Extracellular Space
Activin A Complex
Anatomical Structure Morphogenesis
Androst-4-ene-3,17-dione Biosynthetic Process
Negative Regulation Of Signaling
Animal Organ Morphogenesis
Negative Regulation Of Cell Communication
Positive Regulation Of SMAD Protein Signal Transduction
Regulation Of Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation
Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway
Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of SMAD Protein Signal Transduction
Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway
Type III Transforming Growth Factor Beta Receptor Binding
Enzyme-linked Receptor Protein Signaling Pathway
Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Type II Transforming Growth Factor Beta Receptor Binding
Transforming Growth Factor Beta Receptor Signaling Pathway
Type I Transforming Growth Factor Beta Receptor Binding
Positive Regulation Of Epithelial To Mesenchymal Transition
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Positive Regulation Of Cell Differentiation
Positive Regulation Of Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation
Outflow Tract Septum Morphogenesis
Gland Morphogenesis
Odontogenesis
Regulation Of Cell Differentiation
Positive Regulation Of Signal Transduction
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Epithelial To Mesenchymal Transition
Positive Regulation Of Multicellular Organismal Process
Heart Development
Regulation Of Developmental Process
Cellular Response To Growth Factor Stimulus
Positive Regulation Of Cardiac Epithelial To Mesenchymal Transition
Animal Organ Morphogenesis
Salivary Gland Morphogenesis
Positive Regulation Of Developmental Process
Activin Binding
Response To Growth Factor
Growth Factor Activity
Negative Regulation Of Macrophage Cytokine Production
Cell Surface Receptor Signaling Pathway
Animal Organ Development
Negative Regulation Of Cytokine Production
Secondary Palate Development
Anatomical Structure Morphogenesis
Artery Morphogenesis
Vasculogenesis
Positive Regulation Of Cardiocyte Differentiation
Transforming Growth Factor Beta Receptor Binding
System Development
Cardiac Septum Morphogenesis
Response To Wounding
Roof Of Mouth Development
Cytokine Activity
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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