INHA and FST

Number of citations of the paper that reports this interaction (PMID 2036994)
16

Data Source:
HPRD (in vivo)

		INHA	FST
Gene Name		inhibin, alpha	follistatin
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Photoreceptor Outer Segment Photoreceptor Inner Segment Extracellular Region Inhibin-betaglycan-ActRII Complex Neuronal Cell Body Inhibin A Complex	Extracellular Region Nucleus Cytoplasm
	Molecular Function	Receptor Binding Cytokine Activity Transforming Growth Factor Beta Receptor Binding Hormone Activity Protein Binding Growth Factor Activity Inhibin Binding Protein Heterodimerization Activity	Signal Transducer Activity Protein Binding Heparan Sulfate Proteoglycan Binding Activin Binding
	Biological Process	Skeletal System Development Ovarian Follicle Development Cell Cycle Arrest Signal Transduction Cell Surface Receptor Signaling Pathway Cell-cell Signaling Nervous System Development Male Gonad Development Response To External Stimulus Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Cell Differentiation Erythrocyte Differentiation Regulation Of Cell Proliferation Negative Regulation Of Phosphorylation Hemoglobin Biosynthetic Process Regulation Of Apoptotic Process Regulation Of MAPK Cascade Negative Regulation Of Interferon-gamma Biosynthetic Process Negative Regulation Of B Cell Differentiation Negative Regulation Of Macrophage Differentiation Negative Regulation Of Cell Cycle Positive Regulation Of Follicle-stimulating Hormone Secretion Negative Regulation Of Follicle-stimulating Hormone Secretion Cell Development Regulation Of Cell Cycle SMAD Protein Signal Transduction	Negative Regulation Of Transcription From RNA Polymerase II Promoter Skeletal System Development Hematopoietic Progenitor Cell Differentiation Gamete Generation Pattern Specification Process Female Gonad Development BMP Signaling Pathway Hair Follicle Morphogenesis Negative Regulation Of Activin Receptor Signaling Pathway Odontogenesis Of Dentin-containing Tooth Keratinocyte Proliferation Negative Regulation Of Cell Differentiation Positive Regulation Of Hair Follicle Development
Pathways		Peptide hormone metabolism Glycoprotein hormones Peptide hormone biosynthesis	Antagonism of Activin by Follistatin Signaling by Activin
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: FST INHBA INHBB SIAH1 TGFBR3	9 interactors: BMP5 C8orf33 FN1 INHA INHBA INHBE MEST TK1 TXN
Entrez ID		3623	10468
HPRD ID		00933	00641
Ensembl ID		ENSG00000123999	ENSG00000134363
Uniprot IDs		P05111	P19883
PDB IDs			2B0U 2P6A 3HH2
Enriched GO Terms of Interacting Partners?		Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Follicle-stimulating Hormone Secretion Positive Regulation Of Follicle-stimulating Hormone Secretion Positive Regulation Of Ovulation Regulation Of Follicle-stimulating Hormone Secretion Negative Regulation Of Gonadotropin Secretion Female Gonad Development Development Of Primary Female Sexual Characteristics Positive Regulation Of Apoptotic Signaling Pathway Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Response To Follicle-stimulating Hormone Gonad Development Development Of Primary Sexual Characteristics Enzyme Linked Receptor Protein Signaling Pathway Activin Receptor Signaling Pathway Reproduction Sex Differentiation Regulation Of Signal Transduction Negative Regulation Of Cytokine Biosynthetic Process Negative Regulation Of Signaling Single Organism Reproductive Process Response To Gonadotropin Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Positive Regulation Of Signal Transduction Regulation Of Signaling Reproductive Process Regulation Of Pathway-restricted SMAD Protein Phosphorylation SMAD Protein Signal Transduction Cell Differentiation Negative Regulation Of Hormone Secretion Ovarian Follicle Development Growth Reproductive Structure Development Reproductive System Development BMP Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Hair Follicle Development Hair Cycle Process Cell Development Ovulation Cycle Process Positive Regulation Of Cell Death System Development Hemopoiesis Positive Regulation Of Hormone Secretion Gamete Generation Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Tissue Morphogenesis Erythrocyte Differentiation	Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of Pathway-restricted SMAD Protein Phosphorylation SMAD Protein Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Negative Regulation Of Follicle-stimulating Hormone Secretion Positive Regulation Of Follicle-stimulating Hormone Secretion Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Follicle-stimulating Hormone Secretion Positive Regulation Of Protein Phosphorylation Hemoglobin Biosynthetic Process Negative Regulation Of Gonadotropin Secretion Negative Regulation Of B Cell Differentiation Positive Regulation Of Phosphorylation Negative Regulation Of Interferon-gamma Biosynthetic Process Positive Regulation Of Protein Modification Process Negative Regulation Of Macrophage Differentiation Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Phosphorylation Hemoglobin Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction Regulation Of Phosphorylation Male Sex Differentiation Regulation Of MAPK Cascade Positive Regulation Of Cellular Metabolic Process Regulation Of B Cell Differentiation Regulation Of Phosphorus Metabolic Process Regulation Of Cell Death Negative Regulation Of Interferon-gamma Production Endodermal Cell Differentiation Negative Regulation Of Cytokine Biosynthetic Process Negative Regulation Of B Cell Activation Sex Differentiation Regulation Of Intracellular Signal Transduction Anatomical Structure Development Negative Regulation Of Lymphocyte Differentiation Cell Development Enzyme Linked Receptor Protein Signaling Pathway Negative Regulation Of Myeloid Leukocyte Differentiation Endoderm Formation Positive Regulation Of Metabolic Process Negative Regulation Of Hormone Secretion Negative Regulation Of Immune System Process Response To Stimulus Developmental Process Ovarian Follicle Development Negative Regulation Of Transport Fetal Process Involved In Parturition Negative Regulation Of Myeloid Cell Differentiation
Tagcloud ?		amplification arms choosing codon considering detection fragment is6110 isoniazid katg maba mic minimum mtb multiplex pivotal primers probe qpcr refractory resistant rt snp specificity susceptible taqman thirty zone	activin anthropometric blocking consideration copyright correlate elisa eumenorrheic follicular follistatin gestation luteal menstrual nested periods permit phases postpartum preeclamptic pregnancy pregnant protected reserved rights sought subset throughout towards women
Tagcloud (Difference) ?		amplification arms choosing codon considering detection fragment is6110 isoniazid katg maba mic minimum mtb multiplex pivotal primers probe qpcr refractory resistant rt snp specificity susceptible taqman thirty zone	activin anthropometric blocking consideration copyright correlate elisa eumenorrheic follicular follistatin gestation luteal menstrual nested periods permit phases postpartum preeclamptic pregnancy pregnant protected reserved rights sought subset throughout towards women
Tagcloud (Intersection) ?